CAS: 104-01-8; 4-Methoxyphenylacetic Acid

相似化合物

104-47-2 702-23-8 23786-14-3

上下游产品

CAS号14062-18-1 对甲氧基苯乙酸乙酯 | CAS号23786-14-3 4-甲氧基苯乙酸甲酯 | CAS号702-23-8 4-甲氧基苯乙醇 | CAS号6832-17-3 2-diazonio-1-(4... | CAS号124-38-9 二氧化碳 | CAS号824-94-2 4-甲氧基苄氯 | CAS号14337-31-6 BENZENEMETHANOL... | CAS号60512-57-4 1-(2,2-dibromoe... | CAS号104-47-2 对甲氧基苯乙腈 | CAS号10499-17-9 3-(4-methoxyphe... | CAS号110005-81-7 2-hydroxy-5-(2-... | CAS号4091-50-3 N-甲基-4-甲氧基-beta-苯乙胺 | CAS号3722-56-3 (S)-4′,7-二甲基麦角酚 | CAS号491-80-5 鹰嘴豆芽素A | CAS号34837-88-2 2-(4-甲氧基-3-硝基苯基)乙酸甲酯 | CAS号57676-49-0 4-甲氧基苯乙酰肼 | CAS号123-11-5 4-甲氧基苯甲醛; 对甲氧基苯... | CAS号100-09-4 对甲氧基苯甲酸 | CAS号143589-97-3 (S)-4-Benzyl-3-...

2,2,2-三氯-1-(4-甲氧基苯基)乙醇置于sodium Tetrahydroborate,二苯基二硒醚,Sodium Hydroxide体系中,用 乙醇 用作溶剂,以92%的收率获得对甲氧基苯乙酸
参考文献:醛的一般和实际转化为均聚的羧酸.
标题:醛的一般和实际转化为均聚的羧酸.
摘要:在碱性条件下,醛与三氯甲基甲烷,然后与硼氢化钠或苯基硒基(三乙基)硼酸钠反应,可以高收率得到同系羧酸.该操作简单的过程为其他认证协议提供了一种实用,有效的替代方法.该方法与敏感的醛兼容,包括烯醛和可烯化的醛.它还提供了方便的获取α-单十二烷基羧酸的途径.
Doi:10.1021/ol8016484

专利信息

专利号:WO-2024151344-A9
优先权日:2022-11-18
标题:A device that enables the combinatorial synthesis of small molecule libraries
发明人：COPELAND Gregory; LIU JANE
权利人:BRT BIOTECHNOLOGIES INC
摘要:A device for the synthesis of small molecules on a substrate is provided. The device includes a synthesis plate with vias, and a microfluidic patterning plate with a series ot open-faced channels that can be aligned with the vias on the synthesis plate. The device may be used to synthesize combinatorial libraries of small molecules.

专利号:US-7612210-B2
优先权日:2005-12-05
标题:Process for selective synthesis of enantiomers of substituted 1-(2-amino-1-phenyl-ethyl)-cyclohexanols
发明人：MAHANEY PAIGE ERIN; ANTANE MADELENE MIYOKO; SUN JERRY SHUNNENG
权利人:WYETH CORP
摘要:A process for the enantioselective synthesis of an (S)- or (R)-1-[2-dimethylamino)-1-(methoxyphenyl)ethyl]cyclohexanol and analogues or salt thereof are described. The method involves the steps of (a) reacting an (S) or (R) 4-benzyloxazolidinone with a mixed anhydride of a methyoxyphenylacetic acid under conditions which form a oxazolidinone, (4S)- or (4R)-4-benzyl-3-[methyoxyphenyl]acetyl]-oxazolidin-2-one, (b) treating the (4S)- or (4R)-4-benzyl-3-[(methoxyphenyl)acetyl]-1,3-oxazolidin-2-one with an aprotic amine base and titanium chloride in a chlorinated solvent under conditions which permit formation of the corresponding anion, (c) mixing the corresponding anion with titanium chloride and cylcohexanone under conditions which permit an aldol reaction to form the corresponding (4S)- or (4R)-4-benzyl-3-[(2R)-2-(1-hydroxycyclohexyl)-2-(methoxyphenyl)acetyl]-1,3-oxazolidin-2-one,(d) hydrolyzing the (4S)— or (4R)-4-benzyl-3-[(2R)-2-(1-hydroxycyclohexyl)-2-(methoxyphenyl)acetyl]-1,3-oxazolidin-2-one to form a chiral acid (2S or 2R)-(1-hydroxycyclohexyl)-methoxyphenyl)acetic acid, (e) coupling the chiral phenylacid to a secondary amine to form an amide, and (f) reducing the amide to form an (S) or (R) 1[2-dimethylamino)-1-(methoxyphenyl)ethyl]cyclohexanol or a salt thereof.

专利号:US-2003083352-A1
优先权日:2000-07-31
标 题 :Synthesis of imidazole intermediates
发明人：HELAL CHRISTOPHER J
权利人:PFIZER
摘要:The invention provides a method for synthesis of compounds of formula n n n wherein R 1 and R 19 are as defined. Compounds of formula 12 are useful as intermediates for synthesizing compounds having pharmacological activity inhibiting cdk5, cdk2, and GSK-3.

专利号:US-4824532-A
优先权日:1987-01-09
标题:Process for the electrochemical synthesis of carboxylic acids
发明人：MOINGEON MARIE-ODILE; CHAUSSARD JACQUES; TROUPEL MICHEL; SABOUREAU CHRISTOPHE
权利人:AEROSPATIALE
摘要:The invention relates to a process for the electrosynthesis of carboxylic acids of general formula R-COOH in which R is an organic radical by the electrochemical reduction, in the presence of carbon dioxide, of organic compounds corresponding to the general formula R-Y in which R is the above-mentioned organic radical and Y is a hetero atom-containing radical, the hetero atom of the radical Y, chosen from the group consisting of oxygen, nitrogen, sulphur andphosphorus, being directly linked to a carbon atom of the radical R by a single covalent linkage. When the hetero atom is nitrogen or phosphorus, the radical Y is an ammonium or phosphonium radical respectively. The anode, which is consumed during the electrosynthesis, is made of a metal chosen from the group consisting of reducing metals and their alloys, preferably made of magnesium, aluminium or zinc. This process without catalyst is very simple to perform and enables a cell with a single compartment to be employed. The carboxylic acids are commonly employed in the chemical industry, especially as intermediates for the synthesis of pharmaceutical products or of products used in plant protection.

专利号:US-9409855-B2
优先权日:2012-07-25
标 题 :Asymmetric synthesis of (−)-venlafaxine using organocatalyst
发明人：CHAVAN SUBHASH PRATAPRAO; GARAI SUMANTA; PAWAR KAILASH PRALHAD
权利人:COUNCIL SCIENT IND RES
摘要:The patent discloses an asymmetric synthesis of (−)-venlafaxine using an organocatalyst via a unified strategy employing organcatalytic Michael addition, regio-selective dehydration and selective epoxide ring opening.

专利号:US-9206222-B2
优先权日:2009-06-29
标题:Solid phase peptide synthesis of peptide alcohols
发明人：CAUSSIL-AMBLARD MURIEL; MARTINEZ JEAN; TAILHADES JULIEN
权利人:CAUSSIL-AMBLARD MURIEL; MARTINEZ JEAN; TAILHADES JULIEN; CENTRE NAT RECH SCIENT
摘要:The present invention relates to the synthesis of depsipeptides on solid phase support. Said depsipeptides are then implicated in a solution phase O—N acyl shift enabling to obtain the corresponding peptide alcohols.