CAS: 443-88-9; 2-Fluoro-1,3-Dimethylbenzene

上下游产品

CAS号87-62-7 2,6-二甲基苯胺 | CAS号876-99-3 (2,6-dimethylph... | CAS号2366-75-8 5-tert-butyl-2-... | CAS号608-28-6 1,3-二甲基-2-碘苯 | CAS号100379-00-8 2,6-二甲基苯硼酸 | CAS号108-38-3 间二甲苯 | CAS号120-82-1 1,2,4-三氯苯 | CAS号98-19-1 5-叔丁基间二甲苯 | CAS号6279-89-6 4-叔丁基-2,6-二甲基硝基苯 | CAS号42014-60-8 4-叔丁基-2,6-二甲基-苯胺 | CAS号1583-65-9 2-氟间苯二甲酸 | CAS号1736-85-2 2-氟-1,3-二甲基硝基苯 | CAS号1840-27-3 4-氟-3,5二甲基苯胺 | CAS号914301-44-3 2-氟-3-(甲氧基羰基)苯甲酸

2,6-二甲基苯硼酸置于乙酰基次氟酸酯体系中,用 溶剂黄146,乙腈 作为反应溶剂,化学反应 0.17H,以85%的收率获得产物2,6-二甲基氟苯
参考文献:直接由稀释氟制成的次氟乙酰基氟氟化芳基硼酸
标题:直接由稀释氟制成的次氟乙酰基氟氟化芳基硼酸
摘要:使用容易获得的acof溶液,可以高收率地将含有edg的芳基硼酸或频哪醇酯转化为相应的芳基氟化物.在与对位含ewg的芳基硼酸发生反应时,会产生两种竞争力:一种将氟化作用直接发生在硼酸上,另一种将其引导向ipso取代.当ewg间位为硼酸时,Ipso向硼部分的取代以非常好的产率发生.
DOI:10.1021/jo401832F

专利信息

专利号:US-4739073-A
优先权日:1983-11-04
标题:Intermediates in the synthesis of indole analogs of mevalonolactone and derivatives thereof
发明人：KATHAWALA FAIZULLA G
权利人:SANDOZ PHARMACEUTICALS CORP
摘要:Compounds of the formula wherein one of R and Ro is and the other is primary or secondary C1-6alkyl not containing an asymmetric carbon atom, C3-6cycloalkyl or phenyl(CH2)m-, wherein R4 is hydrogen, C1-3alkyl, n-butyl, i-butyl, t-butyl, C1-3alkoxy, n-butoxy, i-butoxy, trifluoromethyl, fluoro, chloro, phenoxy or benzyloxy, R5 is hydrogen, C1-3alkyl, C1-3alkoxy, trifluoromethyl, fluoro, chloro, phenoxy or benzyloxy, R5a is hydrogen, C1-2alkyl, C1-2alkoxy, fluoro or chloro, and m is 1, 2 or 3, with the provisos that both R5 and R5a must be hydrogen when R4 is hydrogen, R5a must be hydrogen when R5 is hydrogen, not more than one of R4 and R5 is trifluoromethyl, not more than one of R4 and R5 is phenoxy, and not more than one of R4 and R5 is benzyloxy, R2 is hydrogen, C1-3alkyl, n-butyl, i-butyl, t-butyl, C3-6cycloalkyl, C1-3alkoxy, n-butoxy, i-butoxy, trifluoromethyl, fluoro, chloro, phenoxy or benzyloxy, R3 is hydrogen, C1-3alkyl, C1-3alkoxy, trifluoromethyl, fluoro, chloro, phenoxy or benzyloxy, with the provisos that R3 must be hydrogen when R2 is hydrogen, not more than one of R2 and R3 is trifluoromethyl, not more than one of R2 and R3 is phenoxy, and not more than one of R2 and R3 is benzyloxy, X is -(CH2)n- or -CH=CH-, wherein n is 0, 1, 2 or 3, and Z is wherein R6 is hydrogen or C1-3alkyl, and R7 is hydrogen, C1-3alkyl, n-butyl, i-butyl, t-butyl, benzyl or M, wherein M is a pharmaceutically acceptable cation, the use thereof for inhibiting cholesterol biosynthesis and lowering the blood cholesterol level, and, therefore, in the treatment of hyperlipoproteinemia and atherosclerosis, pharmaceutical compositions comprising such compounds and processes for and intermediates in the synthesis of such compounds.

专利号:US-5354772-A
优先权日:1982-11-22
标 题:Indole analogs of mevalonolactone and derivatives thereof
发明人：KATHAWALA FAIZULLA G
权利人:SANDOZ PHARMACEUTICALS CORP
摘要:Compounds of the formula wherein one of R and Ro is and the other is primary or secondary C1-6alkyl not containing an asymmetric carbon atom, C3-6cycloalkyl or phenyl-(CH2)m-, wherein R4 is hydrogen, C1-3alkyl, n-butyl, i-butyl, t-butyl, C1-3alkoxy, n-butoxy, i-butoxy, trifluoromethyl, fluoro, chloro, phenoxy or benzyloxy, R5 is hydrogen, C1-3alkyl, C1-3alkoxy, trifluoromethyl, fluoro, chloro, phenoxy or benzyloxy, R5a is hydrogen, C1-2alkyl, C1-2alkoxy, fluoro or chloro, and m is 1, 2 or 3, with the provisos that both R5 and R5a must be hydrogen when R4 is hydrogen, R5a must be hydrogen when R5 is hydrogen, not more than one of R4 and R5 is trifluoromethyl, not more than one of R4 and R5 is phenoxy, and not more than one of R4 and R5 is benzyloxy, R2 is hydrogen, C1-3alkyl, n-butyl, i-butyl, t-butyl, C3-6cycloalkyl, C1-3alkoxy, n-butoxy, i-butoxy, trifluoromethyl, fluoro, chloro, phenoxy or benzyloxy, R3 is hydrogen, C1-3alkyl, C1-3alkoxy, trifluoromethyl, fluoro, chloro, phenoxy or benzyloxy, with the provisos that R3 must be hydrogen when R2 is hydrogen, not more than one of R2 and R3 is trifluoromethyl, not more than one of R2 and R3 is phenoxy, and not more than one of R2 and R3 is benzyloxy, X is -(CH2)n- or -CH=CH-, wherein n is 0, 1, 2 or 3, and Z is wherein R6 is hydrogen or C1-3alkyl, and R7 is hydrogen, R7b or M, wherein R7b is a physiologically acceptable and hydrolyzable ester group, and M is a pharmaceutically acceptable cation, the use thereof for inhibiting cholesterol biosynthesis and lowering the blood cholesterol level, and therefore, in the treatment of hyperliopoproteinemia and atherosclerosis, pharmaceutical compositions comprising such compounds and processes for and intermediates in the synthesis of such compounds.

专利号:US-7615300-B2
优先权日:2005-08-30
标 题 :Development of novel proton-conductive polymers for proton exchange membrane fuel cell (PEMFC) technology
发明人：BAE CHULSUNG
权利人:REGENTS UNIVERSITY AND COMMUNI
摘要:New thermally and chemically stable sulfonic acid-containing polymers are synthesized via post-sulfonation of aromatic polymers. These new polymers provide unique benefits to proton exchange membrane fuel cell technology (“PEMFCâ€?). As a sulfonic acid moiety can be easily installed into an aromatic ring via electrophilic sulfonation, even in the presence of an electron-withdrawing substituent such as —F, rigid polymers consisting of aromatic rings at either the side chain or main chain can be prepared with a wide range of substituents and flexibility in properties. Novel synthetic procedures are provided for synthesis of the polymers.

专利号:US-5001255-A
优先权日:1984-12-04
标题:Idene analogs of mevalonolactone and derivatives thereof
发明人：KATHAWALA FAIZULLA G; WATTANASIN SOMPONG
权利人:SANDOZ PHARMACEUTICALS CORP
摘要:Compounds of the formula the use thereof for inhibiting cholesterol biosynthesis and lowering the blood cholesterol level and, therefore, in the treatment of hyperlipoproteinemia and atherosclerosis, pharmaceutical compositions comprising such compounds and processes for and intermediates in the synthesis of such compounds.

专利号:US-9718764-B2
优先权日:2013-03-22
标题:Synthetic building blocks for the production of materials for organic electroluminescence devices
发明人：STOESSEL PHILIPP; PARHAM AMIR HOSSAIN; JATSCH ANJA
权利人:MERCK PATENT GMBH
摘要:The present invention relates to compounds which are suitable as synthesis precursors for the production of electronically active materials for use in organic electroluminescence devices.

专利号:US-10270034-B2
优先权日:2014-05-26
标题 :Tetra-aryl indacenodithiophene-based polycyclic polymers and their use
发明人：MITCHELL WILLIAM; D'LAVARI MANSOOR; WANG CHANGSHENG; SPARROWE DAVID
权利人:MERCK PATENT GMBH
摘要:The present invention relates to compounds comprising a tetra-aryl indacenodithiophene-based structural unit, the synthesis of such compounds as well as their use in organic electronic devices. The invention further relates to organic electronic devices comprising such compounds.