CAS: 39718-00-8; 2-Chlorobenzylmercaptan

该化合物是含有含有芳香化合物的化合物,配有分子式C7H7ClS. 它的特点是一个氯化苯基组,配有硫醇(-SH)功能组,使其成为有机合成的多功能中间体.由于该化合物在核循环替代和混合反应中具有反应性,因此在制药,农用化学品和特殊化学品方面发挥着作用,因此特别受到重视. 它的独特结构允许有选择地进行修改,使复杂分子能够合成.氯和硫醇组的存在提高了其在交叉组合和循环形成中的效用.由于它的细小的气味和潜在的再活性,需要适当处理.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

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合成工艺路线路线简述

    📜邻氯氯苄置于硫脲,Sodium Hydroxide体系中,用 乙醇,水 用作溶剂,化学反应 6.0H,以64%的收率获得2-氯苄硫醇
    参考文献:芳香族化合物の製造方法
    标题:芳香族化合物の製造方法

    海关参考信息

    专利信息


    专利号:US-5218088-A
    优先权日:1989-11-02
    标 题 :Process for preparing dithiophosphate oligonucleotide analogs via nucleoside thiophosphoramidite intermediates
    发明人:GORENSTEIN DAVID; FARSCHTSCHI NASSAR
    权利人:PURDUE RESEARCH FOUNDATION
    摘要:A method for synthesis of oligonucleotide analogs having dithiophosphate internucleosidic linkages is described. Monohalohydrocarbylthiophosphoramidites are utilized to prepare nucleoside thiophosphoramidite intermediates which are activated for nucleoside coupling with tetrazole catalysts. Sulfur oxidation and dehydrocarbylation of the coupled thiophosphite intermediates provide oligonucleotide analogs having achiral dithiophosphate internucleosidic linkages.

    专利号:US-7256177-B2
    优先权日:2003-06-17
    标题 :Lincomycin derivatives possessing antibacterial activity
    发明人:LEWIS JASON G; ANANDAN SAMPATH K; O'DOWD HARDWIN; GORDEEV MIKHAIL F
    权利人:VICURON PHARM INC
    摘要:Novel lincomycin derivatives are disclosed. These lincomycin derivatives exhibit antibacterial activity. The compounds of the subject invention may exhibit potent activities against bacteria, including Gram positive organisms, and may be useful antimicrobial agents. Methods of synthesis and of use of the compounds are also disclosed.

    专利号:US-7361743-B2
    优先权日:2004-02-11
    标 题 :Lincomycin derivatives possessing antibacterial activity
    发明人:LEWIS JASON G; ANANDAN SAMPATH K; O'DOWD HARDWIN; GORDEEV MIKHAIL F; LI LIANSHENG
    权利人:PFIZER
    摘要:Novel lincomycin derivatives are disclosed. These lincomycin derivatives exhibit antibacterial activity. The compounds of the subject invention may exhibit potent activities against bacteria, including Gram positive organisms, and may be useful antimicrobial agents. Methods of synthesis and of use of the compounds are also disclosed.

    专利号:US-7199106-B2
    优先权日:2003-06-17
    标题 :Lincomycin derivatives possessing antimicrobial activity
    发明人:LEWIS JASON G; ANANDAN SAMPATH-KUMAR; O'DOWD HARDWIN; GORDEEV MIKHAIL F
    权利人:VICURON PHARM INC
    摘要:Novel lincomycin derivatives are disclosed. These lincomycin derivatives exhibit antibacterial activity. The compounds of the subject invention may exhibit potent activities against bacteria, including gram positive organisms, and may be useful antimicrobial agents. Methods of synthesis and of use of the compounds are also disclosed.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Huy, P.; Czekelius, C., Science of Synthesis Knowledge Updates, (2019) 2, 162.
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