CAS: 23255-54-1; 2,7-Dihydro-β-Erythroidine

📜Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于sodium Hydroxide体系中,化学反应生成二氢-β-刺桐定
参考文献:Synthetic Support For The α-Erythroidine Structure. The Conversion Of α-To β-Erythrodine1
标题:Synthetic Support For The α-Erythroidine Structure. The Conversion Of α-To β-Erythrodine1
摘要:
Doi:10.1021/ja01548A027

专利信息

专利号:US-9315483-B2
优先权日:2007-09-13
标题 :Synthesis of deuterated catechols and benzo[D][1,3]dioxoles and derivatives thereof
发明人：JONES ANDREW D; ZELLE ROBERT E; SILVERMAN I ROBERT
权利人:CONCERT PHARMACEUTICALS INC
摘要:The present invention provides a convenient and efficient process for the synthesis of d 2 -benzo[d][1,3]dioxoles.

专利号:US-2009011476-A1
优先权日:2005-08-19
标 题 :Gene cluster and method for the biosynthesis of terrequinone a
发明人：HOFFMEISTER DIRK; KELLER NANCY P
权利人:WISCONSIN ALUMNI RES FOUND
摘要:The present invention provides a novel gene cluster containing five genes (tdiA-E) involved in indole alkaloid synthesis. Disruption of tdiB, encoding an enzyme with prenyltransferase activity, transferring dimethylallylpyrophosphate to C-2 of an indole structure, eliminated the production of the antitumor compound terrequinone A, a metabolite not known from A. nidulans . The invention further provides a method for expressing terrequinone A in a host cell and isolating purified terrequinone A therefrom.

专利号:US-8252930-B2
优先权日:2006-07-06
标 题:Azaindole derivatives with a combination of partial nicotinic acetyl-choline receptor agonism and dopamine reuptake inhibition
发明人：STOIT AXEL; COOLEN HEIN K A C; VAN DER NEUT MARTINA A W; KRUSE CORNELIS G
权利人:STOIT AXEL; COOLEN HEIN K A C; VAN DER NEUT MARTINA A W; KRUSE CORNELIS G; SOLVAY PHARM BV
摘要:Azaindole derivatives of formula (I): n nwherein the symbols have the meanings given in the specification, are described. These compounds have a combination of partial nicotinic acetylcholine receptor agonism and dopamine reuptake inhibition. The invention also relates to pharmaceutical compositions containing these compounds, to methods for preparing them, methods for preparing novel intermediates useful for their synthesis, methods for preparing compositions, and uses of such compounds and compositions, for example, their use in administering them to patients to achieve a therapeutic effect in disorders in which nicotinic receptors and/or dopamine transporters are involved, or that can be treated via manipulation of those receptors.

专利号:WO-2009035652-A1
优先权日:2007-09-13
标 题 :Synthesis of deuterated catechols and benzo[d][1,3] dioxoles and derivatives thereof

专利号:US-8592458-B2
优先权日:2005-06-07
标 题 :Alpha7 nicotinic receptor selective ligands
发明人：KEM WILLIAM READE; SOTI FERENC
权利人:KEM WILLIAM READE; SOTI FERENC; UNIV FLORIDA
摘要:The invention relates to the design and synthesis of 3-arylidene-anabaseine compounds that exhibit enhanced selectivity toward alpha7 nicotinic receptors. The compounds are expected to be useful in treating a wide variety of conditions, including neurodegenerative conditions such as Alzheimer's Disease, neurodevelopmental diseases such as schizophrenia, and certain peripherally located inflammations mediated by macrophage infiltration.

专利号:US-2014336387-A1
优先权日:2007-09-13
标题:Synthesis of deuterated catechols and benzo[d][1,3]dioxoles and derivatives thereof