CAS: 2280-28-6; 2-Amino-3-Hydroxy-3-Methylbutanoic Acid

相似化合物

102507-13-1 1217603-41-2 2280-48-0

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CAS号14598-96-0 2-(苄基氨基)-3-羟基-3-甲基丁酸 | CAS号67-64-1 丙酮 | CAS号18801-86-0 Valine, 3-metho... | CAS号33550-37-7 ethyl 3-acetoxy... | CAS号75974-47-9 2-溴-3-甲氧基-3-甲基丁酸 | CAS号33550-36-6 Dimethyl-3,3 di... | CAS号32817-15-5 copper(1+) glycinate | CAS号4374-53-2 3,3-dimethyl-ox... | CAS号7647-01-0 盐酸 | CAS号516-06-3 DL-缬氨酸 | CAS号2280-48-0 D-BETA-羟基缬氨酸 | CAS号102507-19-7 (S)-2-(n-b°C-氨基... | CAS号102507-13-1 N-B°C-3-羟基-L-缬氨酸 | CAS号6642-21-3 2-Butenoic acid...

📜Dimethyl-3,3 Diethoxycarbonyl-1,2 Aziridine置于氢氧化钾体系中,化学反应生成(R)-2-氨基-3-羟基-3-甲基丁酸
参考文献:A Novel Synthesis Of β-Hydroxyvaline
标题:A Novel Synthesis Of β-Hydroxyvaline
摘要:从乙基β,β-二甲基丙烯酸酯经过1,2-二(乙氧羰基)-3,3-二甲基环氧乙烷作为中间体合成β-羟基缬氨酸,展示了一种新的合成该氨基酸的方法.
Doi:10.1139/v71-430

专利信息

专利号:US-4486600-A
优先权日:1982-11-19
标题 :Process for the production of β-hydroxy-α-aminocarboxylic acids
发明人：KLEEMANN AXEL; LEHMANN BERND; DELLER KLAUS
权利人:DEGUSSA
摘要:β-hydroxy-α-aminocarboxylic acids of the formula: ##STR1## where R 1 and R 2 are hydrogen or an alkyl group having 1 to 10 carbon atoms are produced by hydrogenating the correspondingly substituted cyanohydrin in a water containing medium first in the presence of a hydrogenation catalyst and an acid at a temperature between -10° and +40° C. and a hydrogen pressure of less than 10 bar, until per mole of cyanohydrogen employed one mole of hydrogen is taken up and then employing the solution obtained as starting material for a Strecker or Bucherer synthesis of an amino acid.

专利号:US-7060818-B2
优先权日:2003-02-21
标题:Synthesis of macrocyclic tetraamido compounds and new metal insertion process
发明人：HORWITZ COLIN P; GHOSH ANINDYA
权利人:UNIV CARNEGIE MELLON
摘要:An improved method of synthesizing a macrocyclic tetraamido compound includes protecting the amino portion of an amino carboxylic acid to form a protected amino carboxylic acid; exposing the protected amino carboxylic acid to a first solvent, preferably a hydrocarbon solvent, such as toluene or 1,2-dichloroethane, dichloromethane, dibromomethane and 1,2-dibromoethane. The carboxylic acid portion of the protected amino carboxylic acid is then converted to an activated carboxylic acid by one of esterification or acid halide formation, to form a protected amino activated carboxylic acid derivative. The protected amino activated carboxylic acid derivative is reacted with a diamine in the presence of a second solvent, such as THF or ,2-dichloroethane, dichloromethane, dibromomethane and 1,2-dibromoethane, to form a protected diamide diamine intermediate. Following deprotection, the diamide diamine intermediate is reacted with an activated diacid, such as an activated malonate, oxalate or succinate derivative to form the macrocyclic tetraamido compound. The macrocyclic tetraamido compound may further be complexed with a transition metal.

专利号:WO-2004076425-A1
优先权日:2003-02-21
标题:Improved synthesis of macrocyclic tetraamido compounds and new metal insertion process

专利号:US-11230553-B2
优先权日:2016-05-09
标 题:Nannocystin process and products
发明人：WANG ZHANG; HUANG JUN
权利人:UNIV NEW YORK STATE RES FOUND
摘要:Described herein is a process for the total synthesis of macrolactones and macrolactams of formula Iincluding E- and Z-configuration thereof, in particular, nannocystins.

专利号:US-5618808-A
优先权日:1992-07-01
标 题 :Benzothiazepine and benzoxazepine derivatives as cholecystokinin receptor antagonists
发明人：NAGEL ARTHUR A
权利人:PFIZER
摘要:The present invention relates to novel substituted benzothiazepines and benzoxazepines of the formula ##STR1## wherein R 1 , R 2 , R 7 , R 8 , R 9 and X are as defined below, and to novel intermediates used in the synthesis of such compounds. n Such compounds are useful in the treatment and prevention of gastrointestinal disorders, pain and anxiety disorders.

专利号:US-2007243581-A1
优先权日:2004-04-21
标题:Process for Producing Dipeptides
发明人：HASHIMOTO SHIN-ICHI; TABATA KAZUHIKO; NOGUCHI AYAKO; ADACHI YUGO
权利人:HASHIMOTO SHIN-ICHI; TABATA KAZUHIKO; NOGUCHI AYAKO; ADACHI YUGO
摘要:The present invention provides: a protein having dipeptide-synthesizing activity or a protein for dipeptide synthesis; DNA encoding the protein having dipeptide-synthesizing activity or the protein for dipeptide synthesis; a recombinant DNA comprising the DNA; a transformant carrying the recombinant DNA; a process for producing the protein having dipeptide-synthesizing activity; an enzymatic process for producing a dipeptide using the protein having dipeptide-synthesizing activity or the protein for dipeptide synthesis; and a process for producing a dipeptide using, as an enzyme source, a culture of a microorganism or a transformant having the ability to produce the protein having dipeptide-synthesizing activity or the protein for dipeptide synthesis, or the like.