CAS: 22795-99-9; (S)-(1-Ethylpyrrolidin-2-yl)Methanamine

上下游产品

CAS号66158-71-2 (S)-1-acetyl-2-... | CAS号114812-34-9 (S)-(-)-1-乙基-2-... | CAS号66158-68-7 1-[(2s)-2-(羟甲基)... | CAS号66158-70-1 (S)-1-(2-(chlor... | CAS号23356-96-9 L-脯氨醇 | CAS号938-54-5 (S)-(-)-1-乙基-2-... | CAS号147-85-3 脯氨酸 | CAS号7531-52-4 L-脯氨酰胺 | CAS号107188-74-9 (-)-(S)-5-溴-2,3... | CAS号84225-95-6 雷氯必利 | CAS号80125-14-0 瑞莫必利 | CAS号128600-22-6 (-)-(S)-5-BROMO... | CAS号107188-87-4 epidepride

(S)-(-)-1-乙基-2-吡咯烷甲酰胺置于lithium Aluminium Tetrahydride体系中,用 四氢呋喃 用作溶剂,以69%的收率获得(S)-2-(氨甲基)-1-乙基吡咯烷
参考文献:Highly Diastereoselective Synthesis Of Chiral Aminophenolate Zinc Complexes And Isoselective Polymerization Of Rac-Lactide
标题:Highly Diastereoselective Synthesis Of Chiral Aminophenolate Zinc Complexes And Isoselective Polymerization Of Rac-Lactide
摘要:通过改变配体框架中一个苯氧基的正位取代基和一个手性吡咯烷基环的 N-烷基,我们非对映地合成了一种由具有多个立体中心的氨基苯酚配体支持的不纯锌配合物,该配合物在 Rac-Lactide 的聚合过程中显示出很高的等选择性.
Doi:10.1039/c3Cc44980G

专利信息

专利号:US-5468876-A
优先权日:1986-05-22
标题:Intermediates for the stereoconservative synthesis of 1-substituted (S)-and (R)-2-aminomethylpyrrolidines
发明人：FEDERSEL HANS-JUEGEN; HOE THOMAS; RAEMSBY STEN I; STROEM PETER H E
权利人:ASTRA AB
摘要:Disclosed are (R)- and (S)-isomers of the compounds of the Formulas II and III with at least 95% optical purity ##STR1## wherein R 1 and R 2 are the same or different and represent a hydrogen atom, a lower alkyl, lower alkenyl or lower alkynyl group, a cycloalkyl group or a group (CH 2 ) m Ph, wherein m is 0-3 and Ph is a substituted or unsubstituted phenyl group. n These compounds are intermediates in the stereoconservative synthesis of 1-substituted (S)- and (R)-2-aminomethylpyrrolidines.

专利号:WO-8707271-A1
优先权日:1986-05-22
标 题 :A stereoconservative synthesis of 1-substituted (s)- and (r)-2-aminomethylpyrrolidines and intermediates thereto

专利号:US-5300660-A
优先权日:1986-05-22
标 题:Efficient stereoconservative synthesis of 1-substituted (S)- and (R)-2-aminomethylpyrrolidines and intermediates thereto

专利号:EP-0270596-A1
优先权日:1986-05-22
标题 :A stereoconservative synthesis of 1-substituted (s)- and (r)-2-aminomethylpyrrolidines and intermediates thereto

专利号:FI-95028-C
优先权日:1986-05-22
标题 :Efficient, stereostructured synthesis of 1-substituted (S) - and (R) -2-aminomethylpyrrolidines and synthetic intermediates

专利号:CN-103804265-B
优先权日:2012-11-08
标 题:A kind of synthesis and aftertreatment method of sulpiride or its optical isomer