CAS: 1193-47-1; 2,2-Dimethylcyclohexanone

该化合物是一种环环状的圆形酮,其特征为附于第二个碳的两组甲基环和碳基位置的一组氯酮功能组;该化合物一般是无色的,可粉黄的液,有独特的气味;该化合物在水中具有相对较低的沸点和中度溶解性,同时在乙醇和乙醚等有机溶剂中更易溶解;氯酮功能组的存在有助于其再活性,使其成为有机合成和工业应用中的有用中间体;此外,2-2二甲基环己烷蛋白蛋白展示了氯酮的典型特性,包括能够进行核细胞添加反应;安全考虑包括在通风良好的地区处理该物质,并使用适当的个人防护设备,因为它可能会对皮肤和眼睛产生刺激;

结构式图片

相似化合物

562-46-9 66417-98-9 1193-46-0

欧盟法规

ECHA物质C&L通报

上下游产品

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合成工艺路线路线简述

    📜2-甲基环己酮置于potassium Tert-Butylate,Sodium Methylate,Potassium Carbonate体系中,用 四氢呋喃,丙酮,甲苯 用作溶剂,化学反应 24.17H,反应生成2,2-二甲基环己酮
    参考文献: Opsin-Binding Ligands,Compositions And Methods Of Use[fr] Ligands De Liaison à Une Opsine,Compositions Et Procédés D'Utilisation
    标题: Opsin-Binding Ligands,Compositions And Methods Of Use[fr] Ligands De Liaison à Une Opsine,Compositions Et Procédés D'Utilisation
    摘要:披露了一些化合物,可用于治疗由于或与在眼睛中积累的有毒视觉循环产物有关的眼科疾病,例如干性成人黄斑变性,以及由于或与突变视蛋白的错误折叠和/或视蛋白的错误定位有关的疾病.还描述了这些化合物单独或与其他治疗剂联合使用的组合物,以及使用这些化合物和/或组合物的治疗方法.还披露了合成这些药剂的方法.

    海关参考信息

    专利信息


    专利号:US-9388131-B2
    优先权日:2011-04-27
    标题:Automated synthesis of small molecules using chiral, non-racemic boronates
    发明人:BURKE MARTIN D; LI JUNQI; GILLIS ERIC P
    权利人:UNIV ILLINOIS
    摘要:Provided are methods for making and using chiral, non-racemic protected organoboronic acids, including pinene-derived iminodiacetic acid (PIDA) boronates, to direct and enable stereoselective synthesis of organic molecules. Also provided are methods for purifying PIDA boronates from solution. Also provided are methods for deprotection of boronic acids from their PIDA ligands. The purification and deprotection methods may be used in conjunction with methods for coupling or otherwise reacting boronic acids. Iterative cycles of deprotection, coupling, and purification can be performed to synthesize chiral, non-racemic compounds. The methods are suitable for use in an automated chemical synthesis process. Also provided is an automated small molecule synthesizer apparatus for performing automated stereoselective synthesis of chiral, non-racemic small molecules using iterative cycles of deprotection, coupling, and purification.

    专利号:WO-2017178716-A1
    优先权日:2016-04-14
    标题 :Method for the synthesis of a mineral oxide using an organic acid insoluble in water
    发明人:PARMENTIER FRANÇOIS
    权利人:PARMENTIER FRANÇOIS
    摘要:The invention relates to a method for the synthesis of precipitated silica from an aqueous solution comprising a silicate ion and an alkaline cation, said method being characterized in that the silicate ion is precipitated by a low-volatility organic acid having more than four carbon atoms.

    专利号:US-5698600-A
    优先权日:1995-10-24
    标题:Process for the production of bisphenols with the use of new cocatalysts
    发明人:WULFF CLAUS; FENNHOFF GERHARD; EITEL ALFRED
    权利人:BAYER AG
    摘要:The invention relates to the synthesis of bisphenols from monophenols and carbonyl compounds such as aldehydes and ketones with concentrated mineral acids such as hydrochloric acid and/or hydrogen chloride gas as acid catalysts and a mercaptan as cocatalyst, which is fixed by an ion-pair bond to a matrix insoluble in the reaction medium.

    专利号:US-8053161-B2
    优先权日:2006-09-25
    标 题 :Resist composition, resin for use in the resist composition, compound for use in the synthesis of the resin, and pattern-forming method using the resist composition
    发明人:WADA KENJI; SAEGUSA HIROSHI
    权利人:FUJIFILM CORP
    摘要:A resist composition comprises: (A) a resin capable of increasing its solubility in an alkali developer by action of an acid; (B) a compound capable of generating an acid upon irradiation with actinic ray or radiation; (C) a resin having at least one of a fluorine atom and a silicon atom; and (D) a solvent, wherein the resin (C) has a degree of molecular weight dispersion of 1.3 or less and a weight average molecular weight of 1.0×10 4 or less.

    专利号:US-9709891-B2
    优先权日:2005-12-09
    标 题:Positive resist composition, resin used for the positive resist composition, compound used for synthesis of the resin and pattern forming method using the positive resist composition
    发明人:KANDA HIROMI; KANNA SHINICHI
    权利人:FUJIFILM CORP
    摘要:A positive resist composition comprises: (A) a resin of which solubility in an alkali developer increases under an action of an acid; (B) a compound capable of generating an acid upon irradiation with actinic rays or radiation; (C) a resin having at least one of a fluorine atom and a silicon atom; and (D) a solvent; and a pattern forming method using the positive resist composition.

    专利号:US-2019315676-A1
    优先权日:2011-04-27
    标 题 :Automated synthesis of small molecules using chiral, non-racemic boronates

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: Tu-Hsin Yan, Et Al. Dichloromethane Activation. Direct Methylenation Of Ketones And Aldehydes With Ch2Cl2 Promoted By Mg/ticl4/thf. Org Lett. 2004 Dec 23;6(26):4961-3.

    合成参考文献


    摘要:Petasis, N. A., Science of Synthesis, (2010) 47, 214.
    摘要:Santana, V. C. S.; Munaretto, L. S.; de Lucca, E. C., Jr., Science of Synthesis Knowledge Updates, (2022) 1, 206.
    摘要:Santana, V. C. S.; Munaretto, L. S.; de Lucca, E. C., Jr., Science of Synthesis Knowledge Updates, (2022) 1, 165.
    摘要:Singh, R. P.; Deng, L., Science of Synthesis: Asymmetric Organocatalysis, (2012) 2, 53.
    摘要:Fleischer, I.; Mejía, E., Science of Synthesis: C-1 Building Blocks in Organic Synthesis, (2013) 1, 149.
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