CAS: 109-57-9; N-Allylthiourea

该化合物是有机化合物,其特征是存在一个Allyl组和一个thiourea功能组,其颜色视其形式和纯度而看似无色的黄色液体或固态,因其具有作为硫化剂作用的能力而闻名该化合物,并经常用于有机合成和各种化学反应中的试剂.Allylthiourea在水中表现出中等溶解性,在有机溶剂中更具溶解性,使其具有多种用途.已经对其生物活动进行了研究,包括潜在的抗沙素特性,及其在某些酶抑制作用进行了研究.然而,必须谨慎地处理Allythiourea,因为它可能构成健康风险,包括毒性和潜在致癌影响.在实验室环境中与该化合物打交道时,应当采取适当的安全措施.

结构式图片

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

CAS号24966-88-9 1-allyl-4,4,6-t... | CAS号57-06-7 异硫氰酸烯丙酯 | CAS号557-11-9 烯丙基脲 | CAS号67917-68-4 2-Thiazolamine,... | CAS号862-64-6 5-oxo-1-(4-sulf... | CAS号7664-41-7 氨 | CAS号111915-74-3 ethyl N'-prop-2... | CAS号21344-73-0 烯丙基-(4-苯基-噻唑-2-基)-胺 | CAS号187737-37-7 propene | CAS号2117-18-2 六乙基二硅氮烷 | CAS号994-49-0 六乙基二硅氧烷 | CAS号30480-64-9 2-amino-5,6-dih... | CAS号10416-80-5 5-methyl-4,5-di... | CAS号557-11-9 烯丙基脲 | CAS号100139-39-7 ethyl N'-prop-2...

合成工艺路线路线简述

  • 合成目标产物 N-Allylthiourea 主要起始原料 Allyl Thiocyanate And 2-Phenylacetamide
  • (文献来源)合成步骤主要原料 Allyl Thiocyanate 和 2-Phenylacetamide
烯丙基脲置于硫化氢体系中,化学反应生成烯丙基硫脲
参考文献:Kitaev,G. A.; Uritskaya,A. A.; Yatlova,L. E.,Russian Journal Of Applied Chemistry,1994,Vol. 67,# 10.1,P. 1415-1418
标题:Kitaev,G. A.; Uritskaya,A. A.; Yatlova,L. E.,Russian Journal Of Applied Chemistry,1994,Vol. 67,# 10.1,P. 1415-1418

海关参考信息

专利信息


专利号:US-11512097-B2
优先权日:2019-11-25
标题 :Heterocyclic compounds as Delta-5 desaturase inhibitors and methods of use
发明人:ALLEN JENNIFER R; BELTRANI MICHELA; BOURBEAU MATTHEW P; DAMYANOVA TEODORA P; LINGARD IAIN; MINATTI ANA E; VINCETTI PAOLO
权利人:AMGEN INC
摘要:The present disclosure provides compounds useful for the inhibition of Delta-5 Desaturase (“D5Dâ€?). The compounds have a general Formula I n nwherein the variables of Formula I are defined herein. This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a metabolic or cardiovascular disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula I.

专利号:US-3558614-A
优先权日:1967-09-05
标题:Synthesis of tetranuclear dyes
发明人:JENKINS PHILIP W
权利人:EASTMAN KODAK CO
摘要:TETRANUCLEAR DYES DERIVED FROM A 2-IMIDAZOLIN-4-ONE, A 2-IMIDAZOLIN-4-THIONE AND A 2-IMIDAZOLIN-4-SELENONE ARE PREPARED IN GOOD YIELDS BY CONDENSING A QUATERNIZED MEROCYANINE DYE DERIVED FROM A 2-IMIDAZOLIN-4-ONE, A 2-IMIDAZOLIN-4-THIONE OR A 2-IMIDAZOLIN4-SELENONE WITH (1) A DIALKOXYALKYL ESTER OF AN ORGANIC ACID, (2) A TRIALKOXY ALKANE OR ARYL COMPOUND, (3) A 3,3-DIALKOZY-1ALKOXYPROPENE, (4) A 1-ANILINO-5-PHENYLIMINO-1,3-PENTADIENE OR (5) A SECOND QUATERNIZED MROCYANINE DYE DERIVED FROM A 2-IMIDAZOLIN-4-ONE, A 2-IMIDAZOLIN-4THIONE OR A 2-IMIDAZOLIN-4-SELENONE, EACH HAVING SUBSTITUTED ON THE CARBON IN THE 2-POSITION A GROUP SUCH AS A B-ACETANILIDOVINYL GROUP, A 4-ACETANILIDO-1,3-BUTADIENYL GROUP, AND A 6-ACETANILIDO-1,3,5-HEXADIENYL GROUP.

专利号:US-9175026-B2
优先权日:2011-03-23
标题:Synthesis of thioether containing trialkoxysilanes
发明人:GARRELL ROBIN L; TUCKER-SCHWARTZ ALEXANDER K
权利人:GARRELL ROBIN L; TUCKER-SCHWARTZ ALEXANDER K; UNIV CALIFORNIA
摘要:The invention relates to a radical-initiated thiol-ene or thiol-yne “clickâ€? reaction that provides a simple and efficient route to diverse trialkoxysilanes. Trialkoxysilanes made in this way are obtained in quantitative to near-quantitative yields with high purity without any or minimal purification. A wide range of functional groups is tolerated in this approach, and even complex alkenes click with the silane precursors. The modular nature of these radical-based thiol-ene or thiol-yne “clickâ€? reactions allows a wide variety of pendant groups to be coupled to silane compounds that can then be coupled to a wide variety surfaces in order to modify their material properties. Consequently, such radical initiated thiol-ene and thiol-yne reactions provide facile and efficient methods for preparing an enormous number of surface-active functional trialkoxysilanes.

专利号:US-2024050916-A1
优先权日:2020-12-14
标题:Biodegradable microcapsules based on composite material and synthesis process
发明人:VRHUNEC ALJOSA; STEFANEC DEJAN; KOTNIK TOMAZ; KRANJC DOMEN
权利人:MIKROCAPS D O O
摘要:The present invention relates to biodegradable microcapsules with a membrane formed of a biodegradable composite material and their synthesis. Biodegradable microcapsules obtained as described in the present invention consist of a core material comprising at least one liquid water-immiscible active component, and a membrane that encloses this core material, the membrane consisting of a composite material comprising a carrier polymer framework and at least one filler deposited into the pores of said carrier polymer framework and deposited onto the surface of said carrier polymer framework, wherein the carrier polymer framework is made of at least one polymer and the filler is a lipophilic biodegradable organic compound which is solid at room temperature and has a melting point above 40° C. The thickness of the membrane is between 20 and 200 nm and the microcapsule diameter is between 1 and 50 pm. Biodegradable microcapsules as described in the present invention are used in the form of aqueous dispersions as additives to fabric softeners, detergents, pesticides, pharmaceutical ingredients, paints, cosmetics products and the like.

专利号:US-2025222420-A1
优先权日:2022-03-15
标题:Biodegradable microcapsules based on crystalline materials and synthesis process
发明人:STEFANEC DEJAN; VRHUNEC ALJOSA; KRANJC DOMEN
权利人:MIKROCAPS D O O
摘要:The present invention relates to a water dispersion of biodegradable microcapsules, with a membrane formed of a biodegradable crystalline material only, i.e. free of polymer framework, and synthesis thereof. Biodegradable microcapsules consist of a core material comprising at least one water-immiscible and water-insoluble active component, and a membrane that encloses this core material, the membrane consisting of a highly crystalline material only, wherein the crystalline material is a lipophilic biodegradable organic compound which is solid at room temperature and has a melting point equal to or above 40° C. Biodegradable microcapsules are in the form of aqueous dispersions and are used primarily for encapsulation of pesticides for use in pest control applications.

专利号:WO-2016110822-A1
优先权日:2015-01-09
标题 :Carboxylic biacyl creatine derivative, uses and method of synthesis thereof
发明人:GARBATI PATRIZIA; MILLO ENRICO; BALESTRINO MAURIZIO; SALIS ANNALISA; ADRIANO ENRICO; DAMONTE GIANLUCA
权利人:UNIV DEGLI STUDI GENOVA
摘要:The invention relates to a novel creatine derivative, the carboxylic biacyl creatine derivative of formula (I) and pharmaceutically acceptable salts thereof, methods of synthesis and the use thereof in the treatment of pathologies due to deficiency of cerebral creatine, such as creatine transporter deficiency, AGAT enzyme deficiency and GAMT enzyme deficiency.
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1: Studzińska R, Kołodziejska R, Kupczyk D, Płaziński W, Kosmalski T. A novel derivatives of thiazol-4(5H)-one and their activity in the inhibition of 11β-hydroxysteroid dehydrogenase type 1. Bioorg Chem. 2018 Sep;79:115-121. doi: 10.1016/j.bioorg.2018.04.014. Epub 2018 Apr 30. doi: 10.1016/j.scitotenv.2018.03.087. Epub 2018 Mar 28. doi: 10.1093/femsec/fiy062. pii: E531. doi: 10.3390/s18020531.
5: Yu H, Qu F, Zhang X, Wang P, Li G, Liang H. Effect of quorum quenching on biofouling and ammonia removal in membrane bioreactor under stressful conditions. Chemosphere. 2018 May;199:114-121. doi: 10.1016/j.chemosphere.2018.02.022. Epub 2018 Feb 6. doi: 10.1007/s11356-017-1155-z. Epub 2018 Jan 10. doi: 10.1016/j.scitotenv.2017.12.116. Epub 2017 Dec 27. doi: 10.1007/s00248-017-1032-9. Epub 2017 Jul 13.
9: Wang J, He Y, Zhu J, Guan H, Huang M. Screening and optimizing of inhibitors for ammonia-oxidizing bacteria in sediments of malodorous river. Appl Microbiol Biotechnol. 2017 Aug;101(15):6193-6203. doi: 10.1007/s00253-017-8318-1. Epub 2017 May 24. doi: 10.1016/j.chemosphere.2017.05.005. Epub 2017 May 3. doi: 10.1021/acs.est.6b05878. Epub 2017 Apr 21. doi: 10.1016/j.biortech.2017.03.022. Epub 2017 Mar 7. doi: 10.1016/j.jinorgbio.2016.12.004. Epub 2016 Dec 10. doi: 10.1016/j.watres.2016.11.041. Epub 2016 Nov 17.

合成参考文献


摘要:Yakugaku Zasshi. Journal of Pharmacy., 94(1419), 1974 []
摘要:Schafer, E. W., Jr., and W. A. Bowles Jr. 1985. Acute oral toxicity and repellency of 933 chemicals to house and deer mice. Archives of Environmental Contamination and Toxicology 14:111-129.
摘要:Schafer, E. W., Jr., and W. A. Bowles Jr. 2004. Toxicity, Repellency of Phytotoxicity of 979 Chemicals to Birds, Mammals and Plants. Research Report No. 04-01. National Wildlife Research Center, Fort Collins, Colorado. 118 pp.
参考文献:10.1023/a:1010202211368
摘要:Whitby CB, Saunders JR, Pickup RW, McCarthy AJ. A comparison of ammonia-oxidiser populations in eutrophic and oligotrophic basins of a large freshwater lake. Antonie Van Leeuwenhoek. 2001 Jun;79(2):179–88. doi: 10.1023/a:1010202211368.
参考文献:10.1007/s002030050738
摘要:Ludwig C, Ecker S, Schwindel K, Rast HG, Stetter KO, Eberz G. Construction of a highly bioluminescent Nitrosomonas as a probe for nitrification conditions. Arch Microbiol. 1999 Jul;172(1):45–50. doi: 10.1007/s002030050738.
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