CAS: 82560-54-1; Benfuracarb

该化合物是已知的在虫害控制方面有效的氨基甲酸酯杀虫剂,主要用作接触和胃毒,针对各种农业害虫;Benfuracarb的化学结构包括一个氨基甲酸酯功能组,这是该类化合物的特点;通常用于作物配方,保护昆虫免受昆虫的危害,但与其它农药相比,在环境中的持久性较低;Benfuracarb对哺乳动物具有中度毒性,并被归类为一种潜在的...

结构式图片

相似化合物

1998216-44-6 16709-30-1 1206094-93-0

欧盟法规

ECHA物质ECHA物质化妆品禁用物质清单C&L通报REACH预注册

上下游产品

3-isopropylaminopropionic acid ethyl ester 2,3-dihydro-2,2-dimethyl-7-benzofuranol methylcarbamate 8H16ClNO2SC8H16ClNO2S

合成工艺路线路线简述

  • 合成目标产物 Benfuracarb 主要起始原料 Ethyl 3-(Isopropylamino)Propanoate
  • (文献来源)合成步骤主要原料 Ethyl 3-(Isopropylamino)Propanoate
📜Diethyl 3,3'-(Disulfanediylbis(Isopropylazanediyl))Dipropionate置于氯,三乙胺体系中,用 氯仿 作为反应溶剂,化学反应 7.0H,反应生成 丙硫克百威
参考文献:克百威衍生物的制备方法
标题:克百威衍生物的制备方法
摘要:本发明公开了一种克百威衍生物的制备方法,包括以下步骤:(1)以胺衍生物和一氯化硫为原料,加入第一缚酸剂和反应溶剂,进行硫化反应,得到第一中间体二硫化物;所述第一缚酸剂为三乙胺;所述反应溶剂为氯仿或二氯甲烷;(2)以第一中间体二硫化物和氯气为原料进行氯化反应,得到第二中间体氮硫氯化物;(3)以第二中间体氮硫氯化物和克百威为原料,加入第二缚酸剂,进行缩合反应,得到克百威衍生物.该制备方法具有工艺简单,产品低毒,纯度和收率高等优点.

海关参考信息

专利信息


专利号:WO-2025056767-A1
优先权日:2023-09-15
标题 :Process for the preparation of enantiomerically enriched aliphatic amines
发明人:BOU HAMDAN FARHAN; GODINEAU EDOUARD; SMEJKAL TOMAS; DUMEUNIER RAPHAEL; BOUSSEMGHOUNE MOHAMED ABDELOUAHAB; BLUM MATHIAS
权利人:SYNGENTA CROP PROTECTION AG
摘要:The present invention relates to a process for the preparation of enantiomerically enriched cyclobutylamines of formula (I) from α-tertiary cyclobutanones and reacting said enantiomerically enriched cyclobutylamines to enantiomerically enriched cyclobutylamides. Such compounds are useful intermediates in the synthesis of microbiocidal thiazole compounds.

专利号:US-10906880-B2
优先权日:2016-01-26
标题:Kind of isothiazole oxime ether-containing strobilurin derivatives and its preparation methods and application
发明人:FAN ZHIJIN; CHEN LAI; GUO XIAOFENG; ZHU YUJIE; QIAN XIAOLIN; MA LIUYONG; ZHANG NAILOU; WANG HAIXIA; ZHANG ZHIMING; XU JINGHUA; SONG YINQI
权利人:UNIV NANKAI
摘要:The present invention is that provided a synthesis method of a series of isothiazole oxime ether containing strobilurin derivatives IV. The present invention relates to 3,4-dichloroisothiazolyl oxime ether strobilurin derivatives, and their chemical structural formula is as shown by IV. n n n n n n n n n n The invention discloses the structural formula of the above compound, the synthesis method and the use as an insecticide, a fungicide, an anti-plant virus agent, and an agriculturally acceptable auxiliary or synergist and a commercial insecticide. The use of a fungicide, an anti-plant virus agent and an acaricide in combination for controlling agricultural, forestry, horticultural plant pests, diseases, virus diseases and preparation methods.

专利号:US-2007232495-A1
优先权日:2006-03-24
标题:Compositions and methods to add value to plant products, increasing the commercial quality, resistance to external factors and polyphenol content thereof
发明人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
权利人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
摘要:The invention is related to compositions and methods that naturally protect plant tissues against ultraviolet radiation and temperature, thus giving protection against sunburn to plants, plant parts, fruits and/or flowers during their development. The invention is also related to compositions and methods to naturally improve the color of plants, plant parts, fruits and/or flowers by inducing the natural synthesis of flavonoids and anthocyanins present in plants. Likewise, the present invention is directed to improving the nutritional value of plants, plant parts, fruits and/or flowers by increasing the normal levels of polyphenolic compounds, especially flavonoids, present therein. Additionally, the present invention is related to compositions and methods that give more resistance to plants, plant parts, fruits and/or flowers against pathogens as bacteria and fungi. Finally, the present invention is related to plants, plant parts, fruits, flowers and/or propagating material treated with the compositions described in the present document.

专利号:WO-2019218027-A1
优先权日:2018-05-18
标题:Core-shell particles
发明人:MEANEY SHANE; TABOR RICHARD; FOLLINK BART
权利人:UNIV MONASH
摘要:The application relates to a core-shell particle having a) a cross-linked polyelectrolyte core, and b) a silica-based shell having covalently bound thereto one or more groups of formula –R–F, wherein R is an organic group and F is a functional moiety. The application also relates to a method of synthesis of a core-shell particle, the method comprising the steps of: a) providing a cross-linked polyelectrolyte core template, b) coating the core template with a silica-based shell, and c) introducing one or more groups of formula –R–F covalently bound to the silica-based shell, wherein R is an organic group and F is a functional moiety.

专利号:WO-2021074309-A1
优先权日:2019-10-16
标 题:1-(3-quinolyl)-3,4-dihydroisoquinoline derivatives as fungicides for combating specific phytopathogens
发明人:WEISS MATTHIAS; QUARANTA LAURA; BOU HAMDAN FARHAN; MAHAJAN ATUL; WILLIAMS SIMON; KILARU JAGADEESH; SEN INDIRA; BIERI STEPHANE; DIGGELMANN MARTIN
权利人:SYNGENTA CROP PROTECTION AG
摘要:1-(3-quinolyl)-3,4-dihydroisoquinoline derivatives of formula (I) as well as a method of combating, preventing or controlling the phytopathogens Mycosphaerella graminicola (Septoria tritici), Fusarium culmorum, Gibberella zeae (Fusarium graminearum) and Monographella nivalis (Microdochium nivale), which comprises applying to the phytopathogen, to the locus of the phytopathogen, or to a plant susceptible to attack by the phytopathogen, or to propagation material thereof, a fungicidally effective amount of a 1-(3-quinolyl)-3,4-dihydroisoquinoline derivative of formula (I). The present description discloses the synthesis of exemplary compounds, formulation examples, relevant biological data (antifungal activity against Mycosphaerella graminicola (Septoria tritici), Fusarium culmorum, Gibberella zeae (Fusarium graminearum) and Monographella nivalis (Microdochium nivale) when spayed on plants), as well as comparative data against three prior art compounds (e.g. pages 52 to 85; formulation examples; examples A1 to A3; table E; compounds E.01 to E.187; biological examples). Exemplary compounds are e.g.: 5-bromo-1-(8-fluoro-3-quinolyl)spiro[4H-isoquinoline-3,1'- cyclopropane] (example A1) 5-bromo-1-(8-fluoro-3-quinolyl)-3,3-dimethyl-4H-isoquinoline (example A2) 1-(8-fluoro-3-quinolyl)-3,3-dimethyl-4H-isoquinoline-5-carbonitrile (example A3)

专利号:WO-2021074311-A1
优先权日:2019-10-16
标题:1-(3-quinolyl)-1,2,3,4-tetrahydroisoquinoline derivatives as fungicides for combating specific phytopathogens
发明人:WEISS MATTHIAS; QUARANTA LAURA; BOU HAMDAN FARHAN; MAHAJAN ATUL; WILLIAMS SIMON; KILARU JAGADEESH; BIERI STEPHANE; DIGGELMANN MARTIN
权利人:SYNGENTA CROP PROTECTION AG
摘要:1-(3-quinolyl)-1,2,3,4-tetrahydroisoquinoline derivatives of formula (I) as well as a method of combating, preventing or controlling the phytopathogens Mycosphaerella graminicola (Septoria tritici), Fusarium culmorum, Gibberella zeae (Fusarium graminearum) and Monographella nivalis (Microdochium nivale), which comprises applying to the phytopathogen, to the locus of the phytopathogen, or to a plant susceptible to attack by the phytopathogen, or to propagation material thereof, a fungicidally effective amount of a 1-(3-quinolyl)-1,2,3,4-tetrahydroisoquinoline derivatives of formula (I). The present description discloses the synthesis of exemplary compounds, formulation examples, relevant biological data (antifungal activity against Mycosphaerella graminicola, Monographella nivalis, Fusarium culmorum and/or Gibberella zeae when spayed on plants) (e.g. pages 47 to 55; examples A1 and A2; compounds E.01 to E.17; table E). An exemplary compounds is e.g.: 3-(5-bromo-3,3-dimethyl-2,4-dihydro-1 H-isoquinolin-1-yl)-8-fluoro- quinoline (example A1)

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

主要参考文献


1: Guo S, Wu Y, Xiao P, Li W. Benfuracarb inhibits body growth and causes oxidative stress in zebrafish (Danio rerio). Chemosphere. 2022 Mar;291(Pt 2):132955. doi: 10.1016/j.chemosphere.2021.132955. Epub 2021 Nov 18. 68(4):637-43. doi: 10.1007/s10616-014-9811-3. Epub 2014 Nov 8.
3: Abass K, Reponen P, Mattila S, Rautio A, Pelkonen O. Comparative metabolism of benfuracarb in in vitro mammalian hepatic microsomes model and its implications for chemical risk assessment. Toxicol Lett. 2014 Jan 13;224(2):290-9. doi: 10.1016/j.toxlet.2013.08.009. Epub 2013 Aug 16. 224(2):300-9. doi: 10.1016/j.toxlet.2013.08.023. Epub 2013 Sep 7. 83(3):348-51. doi: 10.1007/s00128-009-9710-z. Epub 2009 Mar 31. 67(2):209-12. doi: 10.1002/ps.2053. 20(2):143-8. doi: 10.2131/jts.20.143. 108(3):1208-14. doi: 10.1093/jee/tov064. Epub 2015 Apr 4. 69(3):257-66. 56(2):65-71. Japanese. doi: 10.5650/jos.56.65. 76(4):720-7. doi: 10.1007/s00128-006-0979-x. Erratum in: Bull Environ Contam Toxicol. 2006 Aug;77(2):319. Zang, Q [corrected to Zeng, Q]. 71(2 Pt B):555-62. 13(2):105-9. doi: 10.1065/espr2005.10.285. 339(1):61-72. doi: 10.1016/0165-1110(94)00015-5. 112(4):268-70. doi: 10.1007/s004140050247. 12(8):560. doi: 10.3390/bios12080560.
17: Stehrer-Schmid P, Wolf HU. Genotoxic evaluation of three heterocyclic N-methylcarbamate pesticides using the mouse bone marrow micronucleus assay and the Saccharomyces cerevisiae strains D7 and D61.M. Mutat Res. 1995 Dec;345(3-4):111-25. doi: 10.1016/0165-1218(95)90047-0. 102-103:569-73. doi: 10.1016/s0378-4274(98)00250-1.

合成参考文献


参考文献:10.1016/j.chroma.2004.02.078
摘要:Sannino A, Bolzoni L, Bandini M. Application of liquid chromatography with electrospray tandem mass spectrometry to the determination of a new generation of pesticides in processed fruits and vegetables. J Chromatogr A. 2004 May 21;1036(2):161–9. doi: 10.1016/j.chroma.2004.02.078.
参考文献:10.2116/analsci.22.835
摘要:Sasaki H, Yonekubo J, Hayakawa K. A new on-line sample preparation system for the liquid chromatography/time-of-flight mass spectrometry simultaneous analysis of pesticides in river water. Anal Sci. 2006 Jun;22(6):835–40. doi: 10.2116/analsci.22.835.
参考文献:10.1093/jee/tov064
摘要:Yi JH, Perumalsamy H, Sankarapandian K, Choi B-, Ahn Y-. Fumigant Toxicity of Phenylpropanoids Identified in Asarum sieboldii Aerial Parts to Lycoriella ingenua (Diptera: Sciaridae) and Coboldia fuscipes (Diptera: Scatopsidae). Journal of Economic Entomology. 2015 Apr 04;108(3):1208–14. doi: 10.1093/jee/tov064.
📝 需求与反馈
尽可能描述清楚需求与问题信息
×

通知