CAS: 745833-19-6; Ethyl 6-Chloro-2-(2,4-Difluorophenyl)Pyridine-3-Carboxylate
该化合物是一种含氟尼古丁衍生物,可用于制药和农用化学研究,其结构以二氟苯基组和氯代苯丙烯环为特征,有助于其作为合成生物活性化合物的中间体的用途;氟辛烷原子的存在增强了代谢稳定性和亲脂性,使其在药物发现中具有价值;乙基酯混合物为进一步实现功能提供了合成灵活性;该化合物的特点是纯度高且始终如一,确保研究应用的可靠性;其定义明确的化学特性有利于其用于开发新型治疗剂和作物保护化学品;建议在惰性条件下进行适当处理和储存以保持稳定性.
- 英文名称Ethyl 6-Chloro-2-(2,4-Difluorophenyl)Pyridine-3-Carboxylate
- 中文名称6-氯-2-(2,4-二氟苯基)吡啶-3-羧酸乙酯
- IUPAC名称ethyl 6-chloro-2-(2,4-difluorophenyl)nicotinate
- 其它别名2-(2,4-二氟苯)-6-氯烟酸乙酯; Ethyl 2-(2,4-Difluorophenyl)-6-Chloronicotinate
- CAS编号745833-19-6
- MFCD编号:MFCD08460994
- EINECS号:843-656-0
- 分子式:C14H10ClF2NO2分子量:297.69
- 产品CID: 1736110
- 产品分类有机原料→分子砌块→芳杂环类化合物→吡啶类化合物
相似化合物
1219503-87-3 745833-06-1 303146-96-5物理性质
MSDS等安全信息
欧盟法规
C&L通报上下游产品
2-(2,4-difluorophenyl)-3-(ethoxycarbonyl)pyridine 1-oxide合成工艺路线路线简述
📜2-(2,4-Difluorophenyl)-3-(Ethoxycarbonyl)Pyridine 1-Oxide置于三氯氧磷体系中,用 1,2-二氯乙烷 作为反应溶剂,以75%的收率获得产物2-(2,4-二氟苯基)-6-氯吡啶-3-羧酸乙酯
参考文献: Solid Forms Of 2-(2,4-Difluorophenyl)-6-(1-(2,6-Difluorophenyl)Ureido)Nicotinamide[fr] Formes Solides Du 2-(2,4-Difluorophényl)-6-(1-(2,6-Difluorophényl)Uréido)Nicotinamide
标题: Solid Forms Of 2-(2,4-Difluorophenyl)-6-(1-(2,6-Difluorophenyl)Ureido)Nicotinamide[fr] Formes Solides Du 2-(2,4-Difluorophényl)-6-(1-(2,6-Difluorophényl)Uréido)Nicotinamide
海关参考信息
- 2912110000-甲醛
2915110000-甲酸
2933310010-吡啶
2901100000-饱和无环烃 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-8686157-B2
优先权日:2003-02-10
标题:Processes for the facile synthesis of diaryl amines and analogues thereof
发明人：SNOONIAN JOHN R; OLIVER-SHAFFER PATRICIA ANN
权利人:SNOONIAN JOHN R; OLIVER-SHAFFER PATRICIA ANN; VERTEX PHARMA
摘要:The present invention relates to processes for the facile synthesis of diaryl amines and analogues thereof. The processes of the present invention produce diaryl amines in high yield and purity. The present invention also relates to intermediates useful in the process of the present invention.
专利号:US-2007173649-A1
优先权日:2003-02-10
标 题:Processes for the facile synthesis of diaryl amines and analogues thereof
专利号:US-8034950-B2
优先权日:2003-02-10
标题:Processes for the facile synthesis of diaryl amines and analogues thereof
专利号:US-2012157684-A1
优先权日:2003-02-10
标题:Processes for the facile synthesis of diaryl amines and analogues thereof
专利号:US-2004230058-A1
优先权日:2003-02-10
标题:Processes for the facile synthesis of diaryl amines and analogues thereof
专利号:US-7115746-B2
优先权日:2003-02-10
标题:Processes for the facile synthesis of diaryl amines and analogues thereof
