CAS: 540-47-6; Cyclopropyl Methyl Ether

📜1,3-二溴-2-甲氧基丙烷置于sodium Carbonate,Sodium Iodide,锌体系中,化学反应生成 环丙基甲基醚
参考文献:Us2424029
标题:Us2424029

专利信息

专利号:US-6162932-A
优先权日:1995-11-08
标 题 :Stereoselective synthesis of endothelin receptor antagonists
发明人：MILLS ROBERT JOHN; KOWALSKI CONRAD JOHN; PING LI-JENG; GOMBATZ KERRY JOSEPH
权利人:SMITHKLINE BEECHAM CORP
摘要:The present invention is directed to chiral intermediates in a synthetic route for preparing endothelium receptor antagonists of formulae (7B) and (7A). ##STR1##

专利号:WO-9717071-A1
优先权日:1995-11-08
标 题 :Stereoselective synthesis of endothelin receptor antagonists
发明人：MILLS ROBERT JOHN; KOWALSKI CONRAD JOHN; PING LI-JEN; GOMBATZ KERRY JOSEPH
权利人:SMITHKLINE BEECHAM CORP; MILLS ROBERT JOHN; KOWALSKI CONRAD JOHN; PING LI JEN; GOMBATZ KERRY JOSEPH
摘要:The present invention is directed to a synthetic route for preparing endothelium receptor antagonists of formulae (7B) and (7A) and to the chiral intermediates.

专利号:US-2021395185-A1
优先权日:2018-10-18
标 题 :Scalable synthesis of optically active 1-cyclopropylalkyl-1-amines
发明人：DENG DA; DU ZHANQUAN; GROLL KLAUS; HOFEDITZ SABRINA; LAUBE MARION; PANGERL MICHAEL; RINK CHRISTIAN; XIAO QING; ZHU ZHIBIN
权利人:BOEHRINGER INGELHEIM INT
摘要:The present invention provides a new, scalable synthetic method for the preparation of non-racemic 1-cyclopropyl alkyl-1-amines, e.g. (S)-1-cyclopropyl ethyl-1-amine. The method makes use of inexpensive starting materials (such as cyclopropyl methyl ketone and S-(−)-α-phenylethylamine) and is well suited for a large scale, industrial process.

专利号:US-2021395200-A1
优先权日:2018-11-16
标 题:Synthetic processes for the production of 1-((3s,4r)-4-(2,6-difluoro-4-methoxyphenyl)-2-oxopyrrolidin-3-yl)-3-phenylurea
发明人：ORTIZ ADRIAN; BOROVIKA ALINA; KOLOTUCHIN SERGEI; LUZUNG MICHAEL R; NYE JEFFREY A; TAN YICHEN; ZARETSKY SERGE; ZHU JASON J; EASTGATE MARTIN D
权利人:BRISTOL MYERS SQUIBB CO
摘要:Highly efficient processes are provided for preparing key intermediates in the synthesis of compounds (I). The process are broadly applicable and can provide selected components having a variety of substituents. Some intermediates are claimed.

专利号:US-6080862-A
优先权日:1995-11-08
标题 :Stereoselective synthesis of endothelin receptor antagonists
发明人：MILLS ROBERT JOHN; KOWALSKI CONRAD JOHN; PING LI-JENG; GOMBATZ KERRY JOSEPH
权利人:SMITHKLINE BEECHAM CORP
摘要:PCT No. PCT/US96/18084 Sec. 371 Date May 8, 1998 Sec. 102(e) Date May 8, 1998 PCT Filed Nov. 8, 1996 PCT Pub. No. WO97/17071 PCT Pub. Date May 15, 1997The present invention is directed to a synthetic route for preparing endothelium receptor antagonists of formulae (7B) and (7A) and to the chiral intermediates

专利号:WO-9925385-A1
优先权日:1997-11-17
标 题:A method of increasing nucleic acid synthesis with ultrasound
发明人：UNGER EVAN C; MCCREERY THOMAS; SADEWASSER DAVID
权利人:IMARX PHARMACEUTICAL CORP
摘要:The present invention is directed to a method of increasing nucleic acid synthesis in a cell comprising administering to the cell a therapeutically effective amount of ultrasound for a therapeutically effective time such that said administration of said ultrasound results in said increased nucleic acid synthesis. The nucleic acid sequence may comprise an endogenous sequence or an exogenous sequence.