CAS: 5057-99-8; Trans-Cyclopentane-1,2-Diol
该化合物是一个循环二醇,其特征是环球环形环状环状氢氧化物组的交叉配置.这种立体化学具有独特的物理化学特性,包括极地溶剂与其直角相较具有更大的稳定性和溶性.该化合物是有机合成的多功能中间体,特别是在制备手链条,药品和特殊聚合物方面.其硬性周期结构和功能性氢氧基组体对于需要精确立体化学控制的应用具有价值.此外,跨环球-1-2-二醇因其衍生灵活性而具有作为可生物降解材料的建筑块的潜力.其定义完善的立体化学和合成效用强调了其在先进化学研究中的重要性.
- 相似结构搜索
- 产品信息参考
;;;; - InChIKey: VCVOSERVUCJNPR-LXDRQGDMNA-N
- InChI=1S/C5H10O2/c6-4-2-1-3-5(4)7/h4-7H,1-3H2/t4-,5-/m0/s1
- 计算化学: 氢键受体数2.0氢键供体数2可旋转键数0
相似化合物
5057-98-7 63261-45-0 4065-92-3物理性质
MSDS等安全信息
- GHS符号GHS07
- 危险类别特定目标器官毒性 - 单次接触 类别3
皮肤腐蚀/刺激 类别2
严重眼刺激 类别2A - 警示词Warning
- 危险描述H335 |可能引起呼吸道刺激.
H315 |造成皮肤刺激.
H319 |造成严重眼刺激. - 防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
- UN编号NONH for all modes of transport
- 安全声明S22
- 危险类别码May cause irritation; [Aldrich MSDS] See Cyclopentanol.
- WGK Germany3
欧盟法规
ECHA物质C&L通报REACH预注册上下游产品
CAS号142-29-0 环戊烯 | CAS号285-67-6 氧化环戊烯 | CAS号111-30-8 戊二醛 | CAS号7129-41-1 6-噁双环[3.1.0]-3-己烯 | CAS号29974-65-0 1,2-二溴环戊烷 | CAS号29782-81-8 (+/-)-trans-cyc... | CAS号96-41-3 环戊醇 | CAS号3008-40-0 cyclo°Ctane-1,2... | CAS号113625-72-2 trans-2-methoxy... | CAS号110-94-1 戊二酸 | CAS号20520-67-6 acetic acid,(1R... | CAS号26620-22-4 1,2-Cyclopentan... | CAS号29887-56-7 1,2-dimethoxycy... | CAS号930-46-1 (1R,2R)-(-)-反-1... | CAS号63261-45-0 (1S)-反-1,2-环戊二醇 | CAS号285-67-6 氧化环戊烯 | CAS号111-30-8 戊二醛 | CAS号3145-88-8 1,2-环戊烷二胺合成工艺路线路线简述
📜Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于乙醇,镍体系中,化学反应生成 (+/-)-反-1,2-环戊二醇
参考文献:770.脂环族二醇.第六部分 的衍生物环-1,2-二醇:戊烷-1-
标题:770.脂环族二醇.第六部分 的衍生物环-1,2-二醇:戊烷-1-
摘要:
DOI:10.1039/jr9520004026
海关参考信息
- 2905122000-异丙醇
2905310000-1,2-乙二醇
2905320000-1,2-丙二醇
2905142000-仲丁醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-9862745-B2
优先权日:2004-03-30
标题 :Synthesis of boronic ester and acid compounds
发明人：AMMOSCATO VINCE; BISHOP JOHN E; CHIU FANG-TING; GEISER ACHIM; GOMEZ JEAN-MARC; HETT ROBERT; KOELLNER CHRISTOPH; KULKARNI VITHALANAND R; LO YOUNG; MUNK STEPHEN; PICKERSGILL I FRASER
权利人:MILLENNIUM PHARM INC; MILLENNIUM PHARM INC
摘要:The invention relates to the synthesis of boronic ester and acid compounds. More particularly, the invention provides improved synthetic processes for the large-scale production of boronic ester and acid compounds, including the peptide boronic acid proteasome inhibitor bortezomib.
专利号:US-8115002-B2
优先权日:2006-09-20
标 题:Preparation of substituted morphinan-6-ones and salts and intermediates thereof
发明人：WANG PETER X; MOSER FRANK W; CANTRELL GARY L; GROTE CHRISTOPHER W
权利人:WANG PETER X; MOSER FRANK W; CANTRELL GARY L; GROTE CHRISTOPHER W; MALLINCKRODT LLC
摘要:The present invention is directed to processes for the synthesis of morphinan-6-ones and salts, intermediates, and analogs thereof.
专利号:US-8022235-B2
优先权日:2007-06-01
标 题 :Compositions of phospholipid ether boronic acids and esters and methods for their synthesis and use
发明人：PINCHUK ANATOLY; WEICHERT JAMEY P; LONGINO MARC
权利人:CELLECTAR INC
摘要:The present invention discloses boronic acids and esters of phospholipid ether analogs and methods for their synthesis and use. The boronic acids and esters of phospholipid ether analogs described herein can be used in treating cancer and in particular can be used in conjunction with radiation therapy, such as external beam radiation therapy and neutron capture therapy to specifically target and kill cancer cells.
专利号:US-2018265546-A1
优先权日:2004-03-30
标题 :Synthesis of boronic ester and acid compounds
专利号:US-2005240047-A1
优先权日:2004-03-30
标 题:Synthesis of boronic ester and acid compounds
专利号:US-2020157143-A1
优先权日:2004-03-30
标题 :Synthesis of boronic ester and acid compounds
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
参考标题:Chiral Synthesis Via Organoboranes. 45. Asymmetric Hydroboration Of 1-Cyclopentenol Derivatives Using Diisopinocampheylborane. Synthesis Of Optically Active Cyclopentane-1,2-Diol Derivatives Of High Optical Purity作者:Herbert C. Brown,Dhanabalan Murali,Bakthan Singaram |发布日期:1999.6
摘要:The Asymmetric Hydroboration Of 1-Cyclopentenol Derivatives, Such As Ethers, Acetate, Silyl Ether And Borinate, Was Investigated Using Diisopinocampheylborane, Dipc2Bh. The Product Trialkylboranes Were Treated With Excess Of Acetaldehyde To Give The Corresponding Diethyl Boronate Esters. These Boronate Esters On Oxidation Using Alkaline Hydrogen Peroxide Gave Optically Active Trans-Cyclopentane-1,2-Diol
合成参考文献
摘要:Johnson, J. B., Science of Synthesis: Stereoselective Synthesis, (2011) 3, 760.
摘要:Wohlgemuth, R., Science of Synthesis: Biocatalysis in Organic Synthesis, (2015) 2, 550.
摘要:Parmeggiani, F.; Galman, J. L.; Montgomery, S. L.; Turner, N. J., Science of Synthesis, (2019) , 396.
摘要:Stoltz, B. M.; Wright, A. C.; Ebner, D. C.; Park, N., Science of Synthesis: Catalytic Oxidation in Organic Synthesis, (2017) 1, 582.
参考文献:10.1016/s1044-0305(02)00344-6
摘要:Petucci C, Guler L, Kenttämaa HI. Differentiation of stereoisomeric steroids by reactions with phosphenium ions. Journal of The American Society for Mass Spectrometry. 2002 Apr 01;13(4):362–70. doi: 10.1016/s1044-0305(02)00344-6.
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