CAS: 4316-23-8; 4-Methylphthalic Acid

该化合物是二碳基酸衍生物,在芳香环的4位置上有一个甲基替代物,该化合物主要用作有机合成的中间体,特别是在染料,聚合物和特殊化学品的生产中;其甲基组组在某些浓缩和酯化反应中增强反应性,为先进的材料应用提供量身定制的特性;晶体固体显示极地有机溶剂中中等溶性,便于其用于控制反应;在标准条件下,4-甲基硫酸具有明确的熔点和稳定性,是精细化学和制药研究的可靠建筑块.

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63089-50-9 27613-33-8 61099-10-3

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ECHA物质C&L通报REACH预注册

上下游产品

4-methylphthalonitrile diethyl 4-methyl-o-phthalate 2-cyano-5-methyl-benzoic acid methyl ester 2,7-dimethylnaphthalene 4-methylphthalic anhydride 5-methyl-1H-isoindole-1,3-(2H)-dione 1,2-bishydroxymethyl-4-methylbenzene diethyl 4-methyl-o-phthalate

合成工艺路线路线简述

    2-氨基-4-甲基苯甲腈置于盐酸体系中,化学反应生成 4-甲基邻苯二甲酸
    参考文献:Niementowski,Monatshefte Fur Chemie,1891,Vol. 12,P. 625
    标题:Niementowski,Monatshefte Fur Chemie,1891,Vol. 12,P. 625

    海关参考信息

    专利信息


    专利号:US-11434217-B2
    优先权日:2017-12-29
    标 题 :Method for synthesis of lobaric acid and analog thereof
    发明人:YIM JOUNG HAN; KIM IL-CHAN; HAN SE JONG; YOUN UI JOUNG; LEE HONG KUM; LEE JUN HYUCK; KIM TAI KYOUNG; YEO KWON JOO
    权利人:KOREA INST OCEAN SCI & TECH; KOREA INSTITUTE OF OCEAN SCIENCE AND TECH
    摘要:The present invention can synthesize lobaric acid and four analogues thereof, which are five phenolic lichen metabolites isolated from an extract of the Antarctic lichen Stereocaulon alpinum and selectively inhibit PTP1B, by a simple, economic and efficient chemical synthesis method.

    专利号:US-2012301720-A1
    优先权日:2009-11-16
    标题 :Metal island coatings and method for synthesis
    发明人:KOBAN WIELAND; PEUKERT WOLFGANG; KLUPP TAYLOR ROBIN; DISTASO MONICA; BAO HUIXIN; VASYLYEV SERHIY
    权利人:KOBAN WIELAND; PEUKERT WOLFGANG; KLUPP TAYLOR ROBIN; DISTASO MONICA; BAO HUIXIN; VASYLYEV SERHIY; BASF SE
    摘要:The present invention relates to methods for synthesis of metallic island coatings with tunable island coverage and morphology on a variety of substrates. Particularly, the present invention relates to substrates coated with one or more metal islands and the use of said island-coated substrates.

    专利号:WO-2006027069-A1
    优先权日:2004-09-07
    标 题 :Method for producing heterocyclic quaternary ammonium and/or guanidinium compounds
    发明人:DEGEN GEORG; EBEL KLAUS
    权利人:BASF AG; DEGEN GEORG; EBEL KLAUS
    摘要:The invention relates to a method for producing an intermediate product containing a heterocyclic quarternary ammonium and/or guanidium cation, for the synthesis of heterocyclic quaternary ammonium and/or guanidium compounds. According to said method, heterocyclic quaternary ammonium and/or guanidium carboxylates are oxidised with an oxidising agent in the presence of a metal from groups 8 to 10 of the periodical table, at a temperature of between 0 and 250 °C and a pressure of between 0.05 and 20 MPa abs.

    专利号:CN-106800519-B
    优先权日:2017-02-08
    标题 :General Method and Application of Rapid Synthesis of Bridged Bis, Tris and Tetraamide Derivatives by Ultrasonic Irradiation

    专利号:US-2021246112-A1
    优先权日:2017-12-29
    标题:Method for synthesis of lobaric acid and analog thereof

    专利号:CN-106800519-A
    优先权日:2017-02-08
    标题 :General Method and Application of Rapid Synthesis of Bridged Bis, Tris and Tetraamide Derivatives by Ultrasonic Radiation
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    主要参考文献

    [参考文献]: C P Saint, Et Al. A Catabolic Plasmid Involved In 4-Methyl-O-Phthalate And 4-Hydroxy-Iso-Phthalate Degradation In Pseudomonas Cepacia. Fems Microbiol Lett. 1990 Jun 1;57(3):323-8.

    合成参考文献


    摘要:Zhang, H.; Liu, C.; Lei, A., Science of Synthesis: Catalytic Transformations via CH Activation, (2015) 2, 139.
    摘要:V. S. K. Nair and S. Parthasarathy, J. Inorg. Nucl. Chem. 32, 3293 (1970).
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