CAS: 4292-10-8; 2-((3-Dodecanamidopropyl)Dimethylammonio)Acetate

该化合物是属于乙型乙型苯丙胺的氨光表面活性剂,来自酸盐,具有在酸性和碱性环境中有效发挥作用的能力,该化合物一般视温度和浓度而定,以粘粘液液体或固体为特征,以温度和纯度为标志,劳美多丙基丁以其温度为名,适合用于个人护理产品,如香波,洗体和面部清洁剂,呈现出极佳的泡沫特性,强化了配方的粘度,促成富含的浓层.此外,它具有良好的水溶性,并且与各种其他表面活化剂,包括有阴离子,电解和非电离性的类型相容,其生物兼容性和皮肤调节特性使它在化妆配方中成为受欢迎的选择.此外劳美迪多丙型丙基酸经常用于工业应用,包括清洁剂和清洁产品,因为其有效的净化能力和低刺激潜力.

结构式图片

上下游产品

lauric acid dimethylaminopropylamide sodium mon°Chloroacetic acid lauric acid 1-amino-3-(dimethylamino)propane

合成工艺路线路线简述

    N-[3-(二甲氨基)丙基]月桂酰胺,Sodium Monochloroacetic Acid置于碳酸氢钠体系中,用 乙醇,水 作为反应溶剂,以91 %的收率获得产物椰油酰胺丙基甜菜碱
    参考文献:一系列氟醚甜菜碱两性表面活性剂的表面活性:氧的作用
    标题:一系列氟醚甜菜碱两性表面活性剂的表面活性:氧的作用
    摘要:由于 Pfos,Pfoa 及其衍生物因其潜在的生物蓄积性和毒性而被斯德哥尔摩公约禁止,人们试图用短链表面活性剂替代传统的含氟表面活性剂.尽管短链替代品可以减轻生物积累,但表面活性受到了损害.氟工业不断寻求有效的解决方案.在这项工作中,我们制备并研究了一系列氟醚甜菜碱表面活性剂的表面活性和铺展性能.讨论了氧对表面活性的作用.我们发现将氧原子插入氟化链可以增加疏水性,从而增强表面活性.根据经验,一个氧的贡献大约是二氟亚甲基的一半.而且,引入氧使结构多样化,以填补短氟表面活性剂和长氟表面活性剂之间表面活性的空白.总之,这项工作为分子设计提供了基础知识.
    DOI:10.1016/j.Cclet.2022.107961

    海关参考信息

    专利信息


    专利号:US-8703952-B2
    优先权日:2008-12-12
    标题:Synthesis of 9-(arylalkyl)-1,2,3,4-tetrahydro-γ-carboline and analogues and intermediates
    发明人:WILLIAMSON CRAIG; STOREY JOHN MERVYN DAVID
    权利人:WILLIAMSON CRAIG; STOREY JOHN MERVYN DAVID; WISTA LAB LTD
    摘要:The present invention pertains generally to methods of preparing certain 9-(arylalkyl)-1,2,3,4-tetrahydro-γ-carboline compounds and their analogues, and especially to methods of preparing dimebon. The present invention also pertains to methods of preparing certain intermediate compounds which find use in the synthesis of the 9-(arylalkyl)-1,2,3,4-tetrahydro-γ-carboline compounds.

    专利号:US-2023212788-A1
    优先权日:2020-03-26
    标 题:New method for automated on-demand biomolecular array synthesis
    发明人:ZHANG YIXIN; LIN WEILIN
    权利人:UNIV DRESDEN TECH
    摘要:The invention provides an amphiphilic coating for the direct and rapid synthesis of an array of peptides and small molecular compounds on a planar surface of a solid support, comprising a hydrophilic chemical structure and a lipophilic group, wherein said peptides and small molecular compounds differ from spot to spot from each other in the chemical structure, characterized in that said amphiphilic coating possesses low wettability to polar aprotic solvents used in the array synthesis; said amphiphilic coating possessing low wettability is designed that it can be converted to a coating possessing high wettability by hydrolysis of the lipophilic group; and said amphiphilic coating comprises an amino group for the reaction with an electrophilic reagent. The invention further provides a solid support comprising said amphiphilic coating and a method for method for the direct and rapid synthesis of an array of peptides and small molecular compounds on a planar surface of a solid support, wherein said planar surface of a solid support comprises said amphiphilic coating. Said method includes the enhancing of the wettability of a glass surface to organic solvents to realize automated on-demand biomolecular array synthesis comprising both, peptides and small molecular compounds. The amphiphilic surface can be switched to a hydrophilic surface, resulting in high density arrays suitable for protein- and cell-based screening.

    专利号:US-2024082118-A1
    优先权日:2021-05-19
    标 题:Topical compositions and methods of preparing the same
    发明人:ABRAMOVICH SAGI; AVIDOR GAL; LANDA BENZION
    权利人:LANDA LABS 2012 LTD
    摘要:There is disclosed a composition comprising a water-insoluble thermoplastic compound capable of stimulating collagen synthesis (CSSC), the CSSC having a molecular weight of more than 0.6 kDa and being dispersed in a polar carrier as nano-elements having an average diameter of 200 nm or less and a viscosity of 107 mPa·s or less. The nano-elements of CSSC can be capable of stimulating the synthesis of skin proteins and/or enabling the delivery of active agents upon their application to a surface to be treated therewith. Methods for preparing the compositions and uses thereof are also provided.

    专利号:US-2024309142-A1
    优先权日:2023-03-17
    标题 :Capped block copolymers, their synthesis, manufacture, and methods of use
    发明人:MAN VICTOR FUK-PONG; LI XIAOJIN HARRY; CHEN YIQING; PU GANG; HUNT JR CLINTON
    权利人:ECOLAB USA INC
    摘要:This disclosure relates to capped block copolymers, preferably reverse block copolymers capped with a hydrophobic group. Preferred hydrophobic groups include benzyl groups and silyl groups. In a preferred embodiment, the reverse block copolymer has at least two arms, wherein each arm is capped with a hydrophobic group. The disclosure also provides for the synthesis of the capped block copolymers as well as methods of using the capped block copolymers for defoaming and antifoaming applications.

    专利号:EP-1721601-A1
    优先权日:2005-05-11
    标 题 :Use of taurine for enhancing lipid synthesis in the epidermis
    发明人:DOERING THOMAS; WALDMANN-LAUE MARIANNE; WADLE ARMIN; ANDERHEGGEN BERND
    权利人:HENKEL KGAA
    摘要:The present invention is the use of taurine for stimulating the epidermal synthesis of barrier lipids.

    专利号:US-2023111600-A1
    优先权日:2019-12-17
    标题 :Polymeric fatty acid compounds for the treatment of fibrous amino acid-based substrates, especially hair
    发明人:WAGNER ROLAND; STREICHER KATHARINA; ROHMANN LAURA; WENSKE CHRISTIAN; HAVELI SHRUTISAGAR DATTATRAYA
    权利人:MOMENTIVE PERFORMANCE MAT GMBH
    摘要:The present invention is directed at mono-, di- or polyquaternary ammonium compounds of the formula (I) wherein x is 1 to 50, and F can be the same or different and is represented by the general formula (II) wherein at least one of the optionally substituted and optionally functional-group-containing hydrocarbon radicals R 1 , R 2 , R 3 , R 4 or R 5 contains at least one estolide moiety comprising two or more ester or amide moieties. The invention also relates to a process for the synthesis of such compounds, the use of the compounds in cosmetic formulations for skin and hair care, cosmetic compositions for the treatment of fibers, and compositions containing one or more of the compounds for the treatment of hair.
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    主要参考文献


    1: Iijima S, Murayama K, Takayama N, Akiyama T, Sugiyama M, Matsunaga K. [A CASE OF ALLERGIC CONTACT DERMATITIS CAUSED BY DETERGENTS CONTAINING COCAMIDOPROPYL BETAINE IN WHICH AN IMPURITY WAS THE POSSIBLE CAUSATIVE AGENT]. Arerugi. 2022;71(9):1136-1142. Japanese. doi: 10.15036/arerugi.71.1136. 14(6):1212. doi: 10.3390/pharmaceutics14061212.
    3: Morris SAV, Xu L, Ananthapadmanabhan KP, Kasting GB. Surfactant Penetration into Human Skin from Sodium Dodecyl Sulfate and Lauramidopropyl Betaine Mixtures. Langmuir. 2021 Dec 7;37(48):14006-14014. doi: 10.1021/acs.langmuir.1c01867. Epub 2021 Nov 21. 37(29):8714-8725. doi: 10.1021/acs.langmuir.1c00964. Epub 2021 Jul 16.
    242:103853. doi: 10.1016/j.jconhyd.2021.103853. Epub 2021 Jul 1.

    合成参考文献


    摘要:S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118
    摘要:International Journal of Toxicology 31(Suppl. 1):77-111, 2012
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