CAS: 25691-37-6; Boc-Dab-Oh

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80445-78-9 2899-79-8 117106-21-5

上下游产品

CAS号13726-85-7 B°C-L-谷氨酰胺 | CAS号117106-21-5 B°C-Dab(芴甲氧羰基)-OH | CAS号7536-55-2 B°C-L-天冬酰胺 | CAS号24424-99-5 二碳酸二叔丁酯 | CAS号3350-20-7 (S)-4-(((苄氧基)羰基... | CAS号92235-34-2 (S)-叔丁氧羰基-3-氨基-... | CAS号190447-69-9 (S)-4-氨基-2-((叔丁... | CAS号117106-21-5 B°C-Dab(芴甲氧羰基)-OH | CAS号3350-20-7 (S)-4-(((苄氧基)羰基...

在 Palladium On Activated Charcoal体系中,用 乙醇 用作溶剂,20.0~25.0 °C,5.0 Mpa 条件下,以97%的收率获得叔丁氧羰基-L-2,4-二氨基丁酸
参考文献:一种2,4-二氨基丁酸衍生物及其制备方法
标题:一种2,4-二氨基丁酸衍生物及其制备方法
摘要:一种2,4‑二氨基丁酸衍生物及其制备方法,涉及药物合成领域,以天冬氨酸衍生物作为起始物,经过简单的还原,取代反应即可得到2,4‑二氨基丁酸衍生物.区别于现有技术,该方法采用的试剂毒性小,反应条件温和,对设备要求不高,合成步骤简单,能以较高的总收率得到2,4‑二氨基丁酸衍生物,便于实现大规模的工业化生产,能很好的应用于药物合成之中.

专利信息

专利号:US-9574189-B2
优先权日:2005-12-01
标题:Enzymatic encoding methods for efficient synthesis of large libraries
发明人：FRANCH THOMAS; LUNDORF MIKKEL DYBRO; JACOBSEN SØREN NYBOE; OLSEN EVA KAMPMANN; ANDERSEN ANNE LEE; HOLTMANN ANETTE; HANSEN ANDERS HOLM; SØRENSEN ANDERS MALLING; GOLDBECH ANNE; DE LEON DAEN; KALDOR DITTE KIEVSMOSE; SLØK FRANK ABILDGAARD; HUSEMOEN GITTE NYSTRUP; DOLBERG JOHANNES; Jensen Kim Birkebæ; PEDERSEN LENE; NØRREGAARD-MADSEN MADS; GODSKESEN MICHAEL ANDERS; GLAD SANNE SCHRØDER; NEVE SØREN; THISTED THOMAS; KRONBORG TINE TITILOLA AKINLEMINU; SAMS CHRISTIAN KLARNER; FELDING JAKOB; FRESKGÃ…RD PER-OLA; GOULIAEV ALEX HAAHR; PEDERSEN HENRIK
权利人:FRANCH THOMAS; LUNDORF MIKKEL DYBRO; JACOBSEN SØREN NYBOE; OLSEN EVA KAMPMANN; ANDERSEN ANNE LEE; HOLTMANN ANETTE; HANSEN ANDERS HOLM; SØRENSEN ANDERS MALLING; GOLDBECH ANNE; DE LEON DAEN; KALDOR DITTE KIEVSMOSE; SLØK FRANK ABILDGAARD; HUSEMOEN GITTE NYSTRUP; DOLBERG JOHANNES; Jensen Kim Birkebæ; PEDERSEN LENE; NØRREGAARD-MADSEN MADS; GODSKESEN MICHAEL ANDERS; GLAD SANNE SCHRØDER; NEVE SØREN; THISTED THOMAS; KRONBORG TINE TITILOLA AKINLEMINU; SAMS CHRISTIAN KLARNER; FELDING JAKOB; FRESKGÃ…RD PER-OLA; GOULIAEV ALEX HAAHR; PEDERSEN HENRIK; NUEVOLUTION AS
摘要:Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).

专利号:US-11702652-B2
优先权日:2005-12-01
标题:Enzymatic encoding methods for efficient synthesis of large libraries

专利号:US-2009264300-A1
优先权日:2005-12-01
标题 :Enzymatic encoding methods for efficient synthesis of large libraries

专利号:US-2020216836-A1
优先权日:2005-12-01
标题 :Enzymatic encoding methods for efficient synthesis of large libraries

专利号:EP-1957644-B1
优先权日:2005-12-01
标 题 :Enzymatic encoding methods for efficient synthesis of large libraries

专利号:US-2019330618-A1
优先权日:2005-12-01
标题 :Enzymatic encoding methods for efficient synthesis of large libraries