CAS: 1205-91-0; 1,4-Phenylene Diacetate

该化合物是一种有机化合物,其特征是,在准方位上,含有两个附属于苯环的乙氧组,其分子式为C10H10O4, 表明含有10个碳原子,10个氢原子和4个氧原子.该化合物一般是白色的脱白晶固体,在丙酮和乙醇等有机溶剂中可溶解,但水溶解性有限. 1,4-二乙氧苯经常用于有机合成,可以作为生产各种化合物的中间体.它表现出芳香化合物的典型特性,包括在某些条件下的稳定性和再活动性.乙氧组的存在可影响其再活性,使其易受水解和其他化学变.在处理该化合物时,应当采取安全防范措施,因为如果吸入或浸泡,可能会对健康造成危害,而且应当使用适当的防护设备.

结构式图片

相似化合物

1200-06-2 3233-32-7 122-79-2

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号64-19-7 冰醋酸 | CAS号123-31-9 对苯二酚 | CAS号108-24-7 乙酸酐 | CAS号122-79-2 乙酸苯酯 | CAS号150-78-7 对苯二甲醚 | CAS号75-36-5 乙酰氯 | CAS号93-59-4 过氧化氢苯甲酰 | CAS号13031-43-1 4'-乙酰氧基苯乙酮 | CAS号106-51-4 苯醌 | CAS号480-66-0 2',4',6'-三羟基苯乙酮 | CAS号490-78-8 2',5'-二羟基苯乙酮 | CAS号21222-04-8 (3-acetyl-4-hyd... | CAS号288074-68-0 1-(2-hydroxy-5-... | CAS号574-19-6 2'-羟基-'1-乙酰萘 | CAS号118-93-4 邻羟基苯乙酮 | CAS号711-79-5 1'-羟基-2'-乙酰萘 | CAS号144686-00-0 3,5,8-trihydrox... | CAS号123-31-9 对苯二酚

合成工艺路线路线简述

  • 合成目标产物 1,4-Diacetoxybenzene 主要起始原料 Phenyl Acetate
  • (文献来源)合成步骤主要原料 Phenyl Acetate
1,1,4,4-Tetraacetoxy-Cyclohexane置于硫酸,乙酸酐体系中,化学反应生成对二乙酰氧基苯
参考文献:Dimroth; Eber; Wehr,Justus Liebigs Annalen Der Chemie,1926,Vol. 446,P. 141
标题:Dimroth; Eber; Wehr,Justus Liebigs Annalen Der Chemie,1926,Vol. 446,P. 141

海关参考信息

专利信息


专利号:US-2004152905-A1
优先权日:2003-01-31
标题:Universal building blocks and support media for synthesis of oligonucleotides and their analogs
发明人:GUZAEV ANDREI P; MANOHARAN MUTHIAH
摘要:Compounds for the synthesis of oligomeric compounds, particularly oligonucleotides and chemically modified oligonucleotide analogs, are provided. In addition, methods for functionalization of a support medium with a first monomeric subunit and methods for the synthesis of oligomeric compounds utilizing the novel compounds bound to support media are provided.

专利号:US-2004242897-A1
优先权日:2002-07-31
标题 :Universal support media for synthesis of oligomeric compounds
发明人:GUZAEV ANDREI P; MANOHARAN MUTHIAH
摘要:Compounds for the synthesis of oligomeric compounds, particularly oligonucleotides and oligonucleotide mimetics, are provided. In addition, methods for functionalizing a support medium with a first monomeric subunit and methods for the synthesis of oligomeric compounds utilizing the novel compounds bound to support media are provided.

专利号:WO-2004011474-A1
优先权日:2002-07-31
标题:Universal support media for synthesis of oligomeric compounds
发明人:GUZAEV ANDREI P; MANOHARAN MUTHIAH; RAVIKUMAR VASULINGA T; KUMAR RAJU K
权利人:ISIS PHARMACEUTICALS INC; GUZAEV ANDREI P; MANOHARAN MUTHIAH; RAVIKUMAR VASULINGA T; KUMAR RAJU K
摘要:Compounds for the synthesis of oligomeric compounds, particularly oligonucleotide and oligonucleotide mimetics, are provided. In addition, methods for functionalizing a support medium with a first monomeric subunit and methods for the synthesis of oligomeric compounds utilizing the novel compounds bound to support media are provided.

专利号:US-6653468-B1
优先权日:2002-07-31
标 题 :Universal support media for synthesis of oligomeric compounds
发明人:GUZAEV ANDREI P; MANOHARAN MUTHIAH
权利人:ISIS PHARMACEUTICALS INC
摘要:Compounds for the synthesis of oligomeric compounds, particularly oligonucleotides and oligonucleotide mimetics, are provided. In addition, methods for functionalizing a support medium with a first monomeric subunit and methods for the synthesis of oligomeric compounds utilizing the novel compounds bound to support media are provided.

专利号:US-11434217-B2
优先权日:2017-12-29
标 题 :Method for synthesis of lobaric acid and analog thereof
发明人:YIM JOUNG HAN; KIM IL-CHAN; HAN SE JONG; YOUN UI JOUNG; LEE HONG KUM; LEE JUN HYUCK; KIM TAI KYOUNG; YEO KWON JOO
权利人:KOREA INST OCEAN SCI & TECH; KOREA INSTITUTE OF OCEAN SCIENCE AND TECH
摘要:The present invention can synthesize lobaric acid and four analogues thereof, which are five phenolic lichen metabolites isolated from an extract of the Antarctic lichen Stereocaulon alpinum and selectively inhibit PTP1B, by a simple, economic and efficient chemical synthesis method.

专利号:US-8138272-B2
优先权日:2006-05-22
标 题:Preparation of polymer conjugates of therapeutic, agricultural, and food additive compounds
发明人:KONRADI ANDREI W; SMITH JENIFER L
权利人:KONRADI ANDREI W; SMITH JENIFER L; ELAN PHARM INC
摘要:This invention provides an improved synthesis of polymer conjugates of formula (I), n nof agricultural, therapeutic, and food additive compounds. In particular, a process is described for the preparation of conjugates by treating primary or secondary alcohol substituents of active compounds with polymeric nucleophiles using “Mitsunobuâ€? or related reaction conditions.
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主要参考文献

[参考文献]: Amr Awad Ibrahim, Et Al. Mesoporous Tin Oxide-Supported Phosphomolybdic Acid As High Performance Acid Catalysts For The Synthesis Of Hydroquinone Diacetate.Colloids And Surfaces A: Physicochemical And Engineering Aspects.Volume 586, 5 February 2020, 124248

合成参考文献


摘要:Schafer, E. W., Jr., and W. A. Bowles Jr. 1985. Acute oral toxicity and repellency of 933 chemicals to house and deer mice. Archives of Environmental Contamination and Toxicology 14:111-129. https://www.aphis.usda.gov/ws/nwrc/chem-effects-db/S_schafer851.pdf
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