CAS: 1010808-43-1; Thiazol-5-Ylmethyl ((2S,3S,5S)-5-Acetamido-3-Hydroxy-1,6-Diphenylhexan-2-yl)Carbamate

英文名称Thiazol-5-Ylmethyl ((2S,3S,5S)-5-Acetamido-3-Hydroxy-1,6-Diphenylhexan-2-yl)Carbamate
中文名称利托那韦杂质C
IUPAC名称thiazol-5-ylmethyl ((2S,3S,5S)-5-acetamido-3-hydroxy-1,6-diphenylhexan-2-yl)carbamate
其它别名Ritonavir Ep Imp C; Ritonavir Ep Impueity C; 1,3-Thiazol-5-Ylmethyl N-[(1S,2S,4S)-4-(Acetylamino)-1-Benzyl-2-Hydroxy-5-Phenylpentyl]Carbamate; Ritonavir Impurity 3(Ritonavir Ep Impurity C); N-[(1S,2S,4S)-4-(Acetylamino)-2-Hydroxy-5-Phenyl-1-(Phenylmethyl)Pentyl]Carbamic Acid 5-Thiazolylmethyl Ester; Ritonavir Usp Impurity A; Thiazol-5-Ylmethyl N-[(2S,3S,5S)-5-Acetamido-3-Hydroxy-1,6-Diphenylhexan-2-Yl Carbamate; Carbamic Acid, N-[(1S,2S,4S)-4-(Acetylamino)-2-Hydroxy-5-Phenyl-1-(Phenylmethyl)Pentyl]-, 5-Thiazolylmethyl Ester
CAS编号1010808-43-1
MFCD编号:MFCD28358831
FDA UNII编号:8KV2H7R99M
分子式:C25H29N3O4S分子量:467.58
产品CID: 22816
产品分类分析化学 → 标准品 → 药典标准品和杂质标准品

相似结构搜索
InChIKey: LGKRKMCCXYIVTI-XWGVYQGASA-N
InChI=1S/C25H29N3O4S/c1-18(29)27-21(12-19-8-4-2-5-9-19)14-24(30)23(13-20-10-6-3-7-11-20)28-25(31)32-16-22-15-26-17-33-22/h2-11,15,17,21,23-24,30H,12-14,16H2,1H3,(H,27,29)
计算化学: 氢键受体数6.0氢键供体数3.0可旋转键数12.0

MSDS等安全信息

上下游产品

(2S,3S,5S)-5-氨基-2-(N-((5-噻唑基)-甲氧羰基)氨基)-1,6-二苯基-3-羟基己烷 (2S,3S,5S)-5-Amino-2-(N-((5-Thiazolyl)-Methoxycarbonyl)Amino)-3-Hydroxy-1,6-Diphenylhexane 144164-11-4

合成工艺路线路线简述

📜乙酰氯,(2S,3S,5S)-5-氨基-2-(N-((5-噻唑基)-甲氧羰基)氨基)-1,6-二苯基-3-羟基己烷置于4-二甲氨基吡啶体系中,用 N,N-二甲基甲酰胺用作溶剂,化学反应 0.33H,以53.3%的收率获得利托那韦杂质c
参考文献:Wo2008/27932
标题:Wo2008/27932

海关参考信息

2905122000-异丙醇
2905142000-仲丁醇
2905399099-其他二元醇
2905499000-其他多元醇
2905590090-其他无环醇的卤化、磺化等衍生物
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则