CAS: 5894-79-1; Methyl 3-Oxo-2-Phenylpropanoate

上下游产品

CAS号101-41-7 苯乙酸甲酯 | CAS号109-94-4 甲酸乙酯 | CAS号37167-62-7 alpha-溴苯基乙酸甲酯 | CAS号1358418-50-4 N-cyanomethyl-N... | CAS号1358418-45-7 methyl α-(N-cya... | CAS号29810-10-4 methyl α-(N,N-d... | CAS号107635-11-0 methyl α-(N-met... | CAS号1358418-55-9 N-cyanomethyl-N... | CAS号529-64-6 托品酸 | CAS号1570-95-2 2-苯基-1,3-丙二醇 | CAS号1865-29-8 2-苯基丙烯酸甲酯 | CAS号49747-42-4 N-(2-phenylethe... | CAS号3967-53-1 托品酸甲酯

苯乙酸甲酯 以90的收率获得产物alpha-甲酰基苯乙酸甲酯
参考文献:一种制备异丙托溴铵的新方法
标题:一种制备异丙托溴铵的新方法
摘要:本发明公开了一种异丙托溴铵的制备方法,包括以下步骤:以苯乙酸甲酯(ⅲ)为起始原料,经取代反应制备α‑甲酰苯乙酸甲酯(ⅳ);托品醇与溴甲烷反应制备化合物(ⅱ);化合物(ⅱ)与化合物(ⅳ)反应制备化合物(ⅴ),化合物(ⅴ)还原制备异丙托溴铵无水物,再通过精制制备异丙托溴铵(ⅶ),该方法操作简单,安全性高,成本低,更适合工业化生产.

专利信息

专利号:WO-2024112764-A1
优先权日:2022-11-21
标 题:Synthesis of pyrrolo[3,4-c]pyrroles
发明人：LUKE GEORGE P; RODRIGUEZ SONIA; OUELLET STEPHANE G; GORINS GILLES; DIKER KHALID; BEAUDENON AURÉLIE; COUSIN JONATHAN
权利人:NOVO NORDISK HEALTHCARE AG
摘要:Novel synthetic methods of making pyrrolo[3,4- c ]pyrroles, derivatives thereof, and intermediates thereto are provided. Also provided are methods using pyrrolo[3,4- c ]pyrroles in the processes for preparing bioactive compounds ( e.g. PKR Activating Compounds).

专利号:EP-4622958-A1
优先权日:2022-11-21
标 题 :Synthesis of pyrrolo[3,4-c]pyrroles

专利号:US-9359298-B2
优先权日:2011-12-23
标题:Cajanine structure analogous compound, preparation method and use
发明人：LI ZHUORONG; JI XINGYUE; Xue situ; ZHENG GUANGHUI; LI YUHUAN; TAO PEIZHEN; JIANG JIANDONG
权利人:INST MED BIOTECHNOLOGY CAMS
摘要:Provided are cajanine structure analogous compounds, synthesis method and pharmacological effects thereof, the compounds of the present invention having the structure as represented by general formulas I, II, III, IV and V. Also provided are pharmaceutical compositions containing the compounds as active ingredient, and uses thereof; the compounds of the present invention having the pharmacological activities such as anti-virus, anti-virus-infection, nerve protection, anti-metabolic-diseases and the like. Also provided is a chemical total synthesis preparation method of the natural products cajanine, cajanine A and cajanine C. The present invention lays a foundation for the in-depth study and development of the compounds as clinical drugs in the future.