CAS: 550-44-7; 2-Methylisoindoline-1,3-Dione

相似化合物

2142-01-0 3485-84-5 5022-29-7

上下游产品

CAS号88-67-5 邻碘苯甲酸 | CAS号201230-82-2 carbon monoxide | CAS号74-89-5 氨基甲烷 | CAS号67-56-1 甲醇 | CAS号163956-72-7 2-(3-(甲亚磺酰基)丁基)... | CAS号74-88-4 碘甲烷 | CAS号1074-82-4 邻苯二甲酰亚胺钾盐 | CAS号88070-48-8 Benzenecarboxim... | CAS号85-44-9 苯酐 | CAS号74-89-5 氨基甲烷 | CAS号88-99-3 邻苯二甲酸 | CAS号41663-84-7 N-甲基-4-硝基邻苯二甲酰亚胺 | CAS号2593-81-9 1H-Isoindole-1,... | CAS号2043-24-5 1-methyl-5-thio... | CAS号3889-18-7 1-methyldithios... | CAS号19532-98-0 N1,N2-二甲基邻苯二甲酰胺 | CAS号2860-50-6 2-(ethoxymethyl... | CAS号703-80-0 3-乙酰基吲哚 | CAS号81223-73-6 6-乙酰基吲哚

2-甲基-3A,4,7,7Alpha-四氢异吲哚-1,3-二酮置于palladium (II) Trifluoroacetate,Sodium Anthraquinone-2-Sulfonate,氧气,Magnesium Sulfate体系中,用 氯苯 作为反应溶剂,110.0 °C,101.33 Kpa 条件下,反应 24.0H,以94%的收率获得产物n-甲基邻苯二甲酰亚胺
参考文献:钯催化环己烯有氧氧化脱氢反应生成取代芳烃衍生物
标题:钯催化环己烯有氧氧化脱氢反应生成取代芳烃衍生物
摘要:钯(II)催化剂体系已被确定用于取代环己烯有氧脱氢成相应的芳烃衍生物.使用蒽醌-2-磺酸钠(ams)作为助催化剂可提高产品收率.反应中可以耐受多种官能团,并描述了该方法的范围和局限性.展示了环己烯催化脱氢反应生成基于邻苯二甲酰亚胺的 Trpa1 活性调节剂的有效途径.
DOI:10.1021/ja512770U

专利信息

专利号:US-5736626-A
优先权日:1996-01-29
标题:Solid support reagents for the direct synthesis of 3'-labeled polynucleotides
发明人：MULLAH KHAIRUZZAMAN BASHAR; ANDRUS WILLIAM A
权利人:PERKIN ELMER CORP
摘要:The compounds of the invention are exemplified by the class of diglycolate synthesis supports particularly useful as support reagents for the direct synthesis of 3'-labeled polynucleotides. Generally, the compounds of the invention have the structure ##STR1## where T is an acid-cleavable hydroxyl protecting group, e.g., 4,4'-dimethoxytrityl; L 1 is a linker for connecting a 3'-terminal nitrogen to carbon; L 2 and L 3 are linkers for connecting oxygen and carbon; W is a solid support, e.g., CPG or polystyrene; L 4 is a linker for connecting the solid support to nitrogen; R 1 and R 2 are nitrogen substituents, e.g., hydrogen, lower alkyl, nitrogen protecting group, or label; and R 3 through R 7 are carbon substituents, e.g., hydrogen or lower alkyl. In a first particularly preferred embodiment, the synthesis supports of the invention are exemplified by compounds having the structure ##STR2## where DMT is 4,4'-dimethoxytrityl and W is polystyrene. In a second particularly preferred embodiment, the synthesis supports of the invention are exemplified by compounds having the structure ##STR3## where DMT and W are defined above.

专利号:US-2012215002-A1
优先权日:2009-10-09
标 题:Synthesis of optically active intermediate for the preparation of montelukast
发明人：LEFORT LAURENT
权利人:LEFORT LAURENT
摘要:The present invention relates to the synthesis of optically active alcohols by means of enantioselective hydrogenation of ketones in biphasic systems. In particular the present invention relates to the synthesis of an optically active alcohol of general formula (1).

专利号:US-5139940-A
优先权日:1989-10-26
标题 :Activation compounds and methods of synthesis of activation compounds
发明人：ISAACS STEPHEN T; CIMINO GEORGE D; METCHETTE KENNETH C; TESSMAN JOHN W
权利人:ISAACS STEPHEN T; CIMINO GOERGE D; METCHETTE KENNETH C; TESSMAN JOHN W
摘要:The invention is directed to isopsoralen compound compositions that contain a variety of substitutions which yet permit their binding to nucleic acid polymers. Reaction conditions that activate these bound isopsoralens results in covalent crosslinking to the nucleic acid polymers. The resultant complex is inhibited from being a template for the template-directed enzymatic synthesis of a complementary nucleic acid polymer. Beside the isopsoralens compositions, the invention includes their synthesis, the nucleic acid complex production and detection, and the above inhibitory method of use of the isopsoralens.

专利号:US-2023159450-A1
优先权日:2020-05-08
标 题 :Dimers for use in synthesis of peptidomimetics
发明人：AL-ABED YOUSEF; ALTITI AHMAD
权利人:FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH
摘要:Dimers for use in synthesis of peptidomimetics are described. Uses of dimers as synthons in synthesis of azapeptides and other peptidomimetics, azapeptides and other peptidomimetics synthesized from the dimers and uses of azapeptides and other peptidomimetics are also described.

专利号:US-9708317-B2
优先权日:2013-11-25
标 题 :Process for the preparation of 8-(4-aminophenoxy)-4H-pyrido[2,3-B]pyrazin-3-one derivatives
发明人：ZAMBON ALFONSO; NICULESCU-DUVAZ DAN; CHUBB RICHARD; SPRINGER CAROLINE JOY
权利人:CANCER RES TECH LTD; INST OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (THE); OXY SCIENT LTD; THE INST OF CANCER RESEARCH: ROYAL CANCER HOSPITAL
摘要:The present invention pertains generally to the field of organic chemical synthesis, and in particular to certain methods for the synthesis of 8-(4-aminophenyoxy)-4H-pyrido[2,3-b]pyrazin-3-one and related compounds (denoted herein as (3)) from 4-(4-aminophenyoxy)pyridine-2,3-diamine and related compounds (denoted herein as (1)), by reaction with glyoxylic acid (denoted herein as (2)). The compounds (3) are useful in the synthesis of known anti-cancer agents, such as 1-(5-tert-butyl-2-(4-methyl-phenyl)-pyrazol-3-yl)-3-[2-fluoro-4-[(3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea.

专利号:WO-0140193-A1
优先权日:1999-12-03
标题:Method for the synthesis of pyrazolines
发明人：BOLDI ARMEN M
权利人:CHEMRX ADVANCED TECHNOLOGIES I; BOLDI ARMEN M
摘要:The present invention provides a method for the synthesis of compounds of Formula (I). Also claimed are novel intermediates and their methods of synthesis.