CAS: 53940-83-3; (S)-2-Amino-2,3-Dimethylbutanoic Acid

相似化合物

26287-62-7 53940-82-2 169566-81-8

📜2-氨基-2,3-二甲基丁酰胺 反应生成 (S)-(-)-α-甲基缬氨酸
参考文献:Enzymatic Resolution Of α,α-Disubstituted α-Amino Acid Esters And Amides
标题:Enzymatic Resolution Of α,α-Disubstituted α-Amino Acid Esters And Amides
摘要:The Scope And Limitations Of The Enzymatic Resolution Of Alpha,Alpha-Disubstituted Alpha-Amino Acid Amides By An Amino Acid Amidase From Mycobacterium Neoaurum And Of The Corresponding Ethyl Esters With Pig Liver Esterase (Ple) Have Been Studied. Moderate Enantiomeric Excesses Were Obtained With Ple,With Only A Narrow Substrate Specificity. Mycobacterium Neoaurum On The Contrary Yields A Broad Range Of S-Alpha,Alpha-Disubstituted Alpha-Amino Acids 1 And The Corresponding R-Amides 2.
DOI:10.1016/s0957-4166(00)80217-7

专利信息

专利号:WO-9517903-A1
优先权日:1993-12-28
标 题:Modular design and synthesis of oxazolone-derived molecules
发明人：HOGAN JOSEPH C JR; CASEBIER DAVID; FURTH PAUL; TU CHENG
权利人:ARQULE PARTNERS L P; HOGAN JOSEPH C JR; CASEBIER DAVID; FURTH PAUL; TU CHENG
摘要:The design and synthesis of novel oxazolone-derived molecular modules and the use of the modules in the construction of new molecules and fabricated materials is disclosed. The new molecules and fabricated materials are molecular recognition agents useful in the design and synthesis of drugs, and have applications in separations and materials science.

专利号:WO-2008098280-A1
优先权日:2007-02-16
标题:Methods for the synthesis of dicarba bridges in growth hormone peptides
发明人：ROBINSON ANDREA JANE; VAN LIEROP BIANCA; WHELAN AMANDA
权利人:POLYCHIP PHARMACEUTICALS PTY; UNIV MONASH; ROBINSON ANDREA JANE; VAN LIEROP BIANCA; WHELAN AMANDA
摘要:The invention relates to peptides comprising the carboxy terminal sequence of a growth hormone or an analogue of such a peptide in which the disulfide bridge is replaced by a dicarba bridge. Compositions containing such dicarba bridged peptides and method of treating obesity in an animal such as a human comprising administration of such dicarba bridged peptides are also disclosed.

专利号:US-2023364251-A1
优先权日:2020-08-06
标 题:Methods for the synthesis of protein-drug conjugates
发明人：BORCHARDT ALLEN; HUGHES ROBERT MICHAEL
权利人:CIDARA THERAPEUTICS INC
摘要:The present invention relates to intermediates and methods for synthesizing protein-drug conjugates that can be used for the treatment of diseases and related conditions.

专利号:KR-20230118799-A
优先权日:2020-08-06
标题 :Chemical Synthesis of Large Enantiomer Proteins and Uses Thereof

专利号:TW-202220698-A
优先权日:2020-08-06
标题:Methods for the synthesis of protein-drug conjugates

专利号:IL-300418-A
优先权日:2020-08-06
标题 :Chemical synthesis of large and useful mirror image proteins