CAS: 2226-74-6; 5-Azacytidine 5'-Triphosphate
该化合物是一种复杂的有机化合物,具有四氢呋喃环,是一个五人环状环状体,含有多种功能组,包括氨基,氢氧化和磷基,有助于其生物活动和作为药剂的潜力.青米碘的出现表明,它可能与核糖酸或核酸新陈代谢中的酶发生相互作用.根据几个手工业中心的具体配置,它的立体化学对于其生物功能至关重要,因为立体异构体可以表现出显著的不同特性.由于存在可进行氢结合的羟基和氨基溶剂,该化合物很可能在极地溶剂中溶解.总体而言,该物质可能会在医药化学中发挥作用,特别是在开发抗核酸或抗癌剂方面,因为其结构特征类似于核糖或核糖类类类类似物.
- 英文名称5-Azacytidine 5'-Triphosphate
- 中文名称5-氮杂胞苷5'-三磷酸盐
- IUPAC名称((2R,3S,4R,5R)-5-(4-amino-2-oxo-1,3,5-triazin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate
- 其它别名[[[[(2S,3S,4R,5R)-5-(4-Amino-2-Oxo-Pyrimidin-1-Yl)-3,4-Dihydroxy-Oxola N-2-Yl]Amino]Oxy-Hydroxy-Phosphoryl]Oxy-Hydroxy-Phosphoryl]Oxyphosphon Ic Acid; 5'-Azacytidine 5'-Triphosphate; 5-Azacytidine 5'-Triphosphatediscontinued; 4-Amino-1-[5-O-[hydroxy[[hydroxy(Phosphonooxy)Phosphinyl]Oxy]Phosphinyl]-β-D-Ribofuranosyl]-1,3,5-Triazin-2(1H)-One; 4-Amino-1-β-D-Ribofuranosyl-S-Triazin-2(1H)-One 5'-Triphosphate; 5-Azacytidine Triphosphate; 1,3,5-Triazin-2(1H)-One, 4-Amino-1-[5-O-[hydroxy[[hydroxy(Phosphonooxy)Phosphinyl]Oxy]Phosphinyl]-β-D-Ribofuranosyl]-; Citicoline Impurity 15
- CAS编号2226-74-6
- MFCD编号:MFCD15145177
- 分子式:C8H15N4O14P3分子量:484.14
- 产品CID: 1153142
- 产品分类医药中间体 → 嘧啶类化合物
物理性质
MSDS等安全信息
合成工艺路线路线简述
海关参考信息
- 2905122000-异丙醇
2905310000-1,2-乙二醇
2905320000-1,2-丙二醇
2905399001-1,3-丙二醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-10736911-B2
优先权日:2015-12-29
标题 :Use of a DHODH inhibitor in combination with an inhibitor of pyrimidine salvage
发明人：DEANS RICHARD; OKESLI AYSE; MORGENS DAVID; KHOSLA CHAITAN; BASSIK MICHAEL C
权利人:UNIV LELAND STANFORD JUNIOR
摘要:Compounds and methods are provided for the treatment of pathogenic virus infections or cancer. The formulations combine an inhibitor of de novo pyrimidine synthesis, and an inhibitor of a pyrimidine salvage pathway enzyme.
专利号:FR-2927901-A1
优先权日:2008-02-21
标题 :PROCESS FOR THE PREPARATION OF NUCLEOTIDES AND ANALOGUES SUCH AS SYNTHESIS ON SOLUBLE CARRIER AND PREPARED BIOLOGICAL TOOLS
