专利号:US-5665834-A 优先权日:1994-06-20 标 题:Method of polymerizing alpha-olefins with boryl zirconocene organic 1,1-dimetallic compound catalysts 发明人:SREBNIK MORRIS; ZHENG BIN; DELOUX LAURENT 权利人:UNIV TOLEDO 摘要:Boron-zirconium 1,1,-dimetallic organic compounds useful in organic synthesis such as the preparation of alpha-borobromanes. The boron-zirconium compounds include boron and zirconiun, and in particular the synthesis, structure and reactivity of E-chlorobis(cyclopentadienyl)- [1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolane-2-yl)-3,3-dimethylbutenyl]zirconium (IV). The boron-zirconium 1,1-dimetallic compound is used as a polymerization catalyst to polymerize alpha-olefins such as styrene.
专利号:US-2008227851-A1 优先权日:2007-03-12 标题 :Laulimalide and laulimalide analogs 发明人:WENDER PAUL A 权利人:WENDER PAUL A 摘要:Novel laulimalide analogs, methods for the treatment of proliferative disease and processes for the synthesis of laulimalide and novel laulimalide analogs are described.
专利号:EP-1785723-A1 优先权日:2005-11-11 标 题:Micro calorimetric analysis of mammalian cell susceptibility to agents that affect cell growth, metabolism and immune response, and use of micro calorimetric analysis in a transplantation test 发明人:KJELDSEN NAJA JOSLIN 权利人:STRATOS BIO LTD 摘要:Method of determining whether or not an organ for transplantation (from a human donor) or xenotransplantation (from an animal donor) is infected with a microoorganism (which is optionally a virus) comprising n- measuring heat output from the organ to detect activity of said microorganism, or n- forcing expression of latent DNA by using agents that stimulate m-RNA synthesis, n nto thereby determine the presence of a microorganism in the organ.
专利号:US-5468889-A 优先权日:1994-06-20 标题:Boryl zirconocene organic 1,1-dimetallic compounds 发明人:SREBNIK MORRIS; ZHENG BIN; DELOUX LAURENT 权利人:UNIV TOLEDO 摘要:Boron-zirconium 1,1,-dimetallic organic compounds useful in organic synthesis such as the preparation of alpha-bromoboranes. The boron-zirconium compounds include boron and zirconiun, and in particular the synthesis, structure and reactivity of E-chlorobis(cyclopentadienyl)- [1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolane-2-yl)-3,3-dimethylbutenyl]zirconium(IV).
1: Liu Y, Chen X, Li Z, Xu W, Tao W, Wu J, Yang J, Deng Z, Sun Y. Functional Analysis of Cytochrome P450s Involved in Streptovaricin Biosynthesis and Generation of Anti-MRSA Analogues. ACS Chem Biol. 2017 Oct 20;12(10):2589-2597. doi: 10.1021/acschembio.7b00467. Epub 2017 Sep 7. doi: 10.1111/j.1365-2672.2011.05206.x. Epub 2012 Jan 3. doi: 10.1128/AAC.01406-09. Epub 2010 Feb 22. 4: Torres W, Rodríguez RR, Prieto JA. Stereoselective construction of all-anti polypropionate modules: synthesis of the C5-C10 fragment of streptovaricin U. J Org Chem. 2009 Mar 20;74(6):2447-51. doi: 10.1021/jo8026966. 5: Sarabia F, Sánchez-Ruiz A, Martín-Ortiz L, García-Castro M, Chammaa S. Stereoselective synthesis of macrolide-type antibiotics from epoxy amides. Synthesis of the polypropionate chain of streptovaricin u. Org Lett. 2007 Nov 22;9(24):5091-4. Epub 2007 Nov 2. Chinese. Review.
合成参考文献
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