CAS: 12131-44-1; Bis[cinnamyl Palladium(Ii) Chloride]

该化合物是一个以+2氧化状态中的为特征的协调化合物,其特点是其角结构,其中两个中心由来自辛南基酒精的螺(Eur-cyncyligands)连接起来;氯化物的存在有助于化合物的总体稳定性和再活动;氯化物(II)(欧元-辛南基)二,因其在催化中的应用而引人注目,特别是在有机合成中,它作为各种组合反应的催化剂,包括交叉组合过程;该复合物展示了一种独特的协调地理测量,典型的正方形在中心周围形成,这是(II)复合物的常见特征;其再活性可能受到离子的性质和反应条件的影响,使它成为合成有机化学中的一种有价值的工具;此外,化合物的硬质会影响其溶性及其与亚推进剂的催化作用.

英文名称Bis[cinnamyl Palladium(Ii) Chloride]
中文名称氯化钯(π-肉桂基)二聚物
IUPAC名称Bis[cinnamyl palladium(II) chloride]
其它别名Di-; C)-1-Phenyl-2-Propenyl]Dipalladium(Ii); C)-1-Phenyl-2-Propen-1-Yl]Dipalladium; Di- -Chlorobis[(1,2,3- )-1-Phenyl-2-Propen-1-Yl]Dipalladium; Di-Chlorobis[(1,2,3-)-1-Phenyl-2-Propenyl]Dipalladium(Ii), 98Per Cent; Palladium(2+); Prop-2-Enylbenzene; D
CAS编号12131-44-1
MFCD编号:MFCD16621470
EINECS号:688-905-2
分子式:C18H12Cl2Pd2
分子量:518.08
产品CID: 289488

相似结构搜索
产品信息参考
InChIKey: PHDNDSSMEIRHSI-UHFFFAOYSA-L
InChI=1S/2C9H6.2ClH.2Pd/c2*1-2-6-9-7-4-3-5-8-9;;;;/h2*1,3-5,7-8H;2*1H;;/q2*-1;;;2*+2/p-2…
计算化学: 氢键受体数*氢键供体数0.0可旋转键数2.0

MSDS等安全信息

GHS象形图
GHS符号GHS02 & GHS07;
注释: Flame & Exclamation mark
危险类别易燃固体类别1
自热物质类别2
急性毒性类别4(吸入)
急性毒性类别4(经皮)
急性毒性类别4(经口)
皮肤腐蚀/刺激类别2
严重眼刺激类别2
水生慢性毒性类别4
特定目标器官毒性 - 单次接触类别3
水生慢性毒性类别3
严重眼刺激类别2A
警示词Danger(危险)
危险描述H228 |易燃固体.
H252 |大量自热;可能着火.
H332 |吸入有害.
H312 |皮肤接触有害.
H302 |吞咽有害.
H315 |造成皮肤刺激.
H319 |造成严重眼刺激.
H413 |可能对水生生物造成长期有害影响.
H335 |可能引起呼吸道刺激.
H412 |对水生生物有害并具有长期持续影响.
防范说明P261-P280-P284-P304+P340+P312-P305+P351+P338+P310-P403+P233
UN编号UN 2811 6.1 / PGIII
危险品标志T
安全声明36/37-45
危险类别码23-43
WGK Germany3

欧盟法规

C&L通报

合成工艺路线路线简述

专利信息

专利号:US-11718584-B2
优先权日:2019-02-22
标题 :Process for the synthesis anthranilic diamide compounds and intermediates thereof
发明人：KARRI PHANEENDRASAI; PABBA JAGADISH; SHINDE BHARAT UTTAMRAO; KALWAGHE AMOL DNYANESHWAR; MADHAVRAO KAMBLE MARUTI; KLAUSENER ALEXANDER G M; PANMAND DEEPAK SHANKAR
权利人:PI INDUSTRIES LTD
摘要:The present invention disclosed a process for the synthesis of anthranilic diamide compound of formula (I), n n n n n n n n n n wherein, R 1 , R 2 , R 3a , R 3b , R 3c , R 4 , R 5 , R 6 and Z are as defined in the detailed description. The process comprising the step of obtaining a mono- or dicyano substituted aniline compound of formula (IV) which is then converted to an anthranilic acid compound of formula (V) or an anthranilic amide compound of formula (Va). Further, the compound of formula (VI) can be optionally synthesized from compound of formula (IV or V or Va)

专利号:US-12071422-B2
优先权日:2022-02-07
标题 :Process for synthesis of quinazoline compounds
发明人：LEBL RENE; LIM NGIAP KIE; MEIER ROLAND CHRISTOPH; ORCEL UGO JONATHAN; SEDELMEIER JOERG; SHEN JEFF; SIROIS LAUREN ELIZABETH; TIMMERMAN JACOB C; TRACHSEL ETIENNE; WHITE NICHOLAS ANDREW; XU JIE; ZHANG HAIMING; BACHMANN STEPHAN; BASS THOMAS MICHAEL; BIGLER RAPHAEL; BURKHARD JOHANNES ADRIAN; CLAGG KYLE BRADLEY PASCUAL; GOSSELIN FRANCIS; HAN CHONG; KALDRE DAINIS; KELLY SEAN M; HEROLD SEBASTIAN; LEITNER CHRISTIAN
权利人:GENENTECH INC; HOFFMANN LA ROCHE
摘要:Provided herein are methods to synthesize compounds useful in the treatment of cancer where such compounds comprise a quinazolinyl core moiety and at least one stereoisomeric or atropisomeric moiety.

专利号:KR-20230134489-A
优先权日:2021-01-20
标题:Synthesis of polyfluorinated aryl and heteroaryl carboxamides

专利号:TW-202423916-A
优先权日:2020-08-12
标题 :Synthesis of quinazoline compounds

专利号:US-2023250074-A1
优先权日:2022-02-07
标题:Process for synthesis of quinazoline compounds

专利号:US-2025074893-A1
优先权日:2020-08-12
标题 :Synthesis of quinazoline compounds