CAS: 71735-31-4; Bariumpentafluorobenzenesulfonate

专利信息

专利号:US-2010150835-A1
优先权日:2007-02-27
标题:Synthesis of [18F] Fluoromethyl Benzene Using Benzyl Pentafluorobenzenesulfonate
发明人：LANGSTROM BENGT; KARIMI FARHAD; BLOM ELISABETH
权利人:LANGSTROM BENGT; KARIMI FARHAD; BLOM ELISABETH
摘要:The present invention discloses the reactivity of ponytail (“PTâ€?) sulfonates as leaving groups in nucleophilic fluorination reactions. The results showed that using a pentafluorobenzenesulfonate precursor is a suitable leaving group for n. c. a. nucleophilic 18 F-fluorination in synthesis of [ 18 F]fluoromethyl benzene, wherein this is a suitable leaving group for 18F-labeling with moderate reactivity. The PT-precursor seems to be quite stable. In an attempt to purify the crude 18F-labeled product using fluorous solid phase extraction (F-SPE), the radio labeled impurities decreased significantly. This provides an opportunity for utilizing PT methodology in both simple and fast purification methods.

专利号:WO-2004047990-A1
优先权日:2002-11-27
标题:Catalyst for the preparation of carboxylic esters and process for the preparation of carboxylic esters with the same
发明人：WATANABE YOSHIHIRO; KURODA YASUSHI
权利人:SHOWA DENKO KK; WATANABE YOSHIHIRO; KURODA YASUSHI
摘要:The invention provides a catalyst for the synthesis of carboxylic esters from aldehydes through Tishchenko reaction or the like which can dispense with a special cooling unit, permits the synthesis at temperatures above ordinary temperature, and exhibits high selectivity and a long lifetime. A catalyst for the preparation of carboxylic esters by dimerization of aldehydes, which consists of an aluminum alkoxide and at least one compound selected from among sulfonic acids and salts thereof with Groups 4 to 14 metals of the periodic table; preparation of carboxylic esters by dimerization of aldehydes with the catalyst; and a process for the preparation of carboxylic esters, in which the synthesis is conducted at a reaction temperature controlled within the range of 30 to 100°C.

专利号:US-2009318592-A1
优先权日:2005-10-11
标 题 :Process for the Synthesis of Amine Ethers
发明人：FREY MARKUS; BROENNIMANN VALERIE
权利人:CIBA GEIGY CORP
摘要:The present invention relates to novel processes for the preparation of a sterically hindered amine ether by reacting a corresponding sterically hindered amine oxide with a ketone or an aldehyde with at least one reactive H in the presence of a peroxydisulphate. Products obtained by this process may be hydrogenated. The compounds made by these processes are particularly effective in the stabilization of polymer compositions against harmful effects of light, oxygen and/or heat and as flame-retardants for polymers.

专利号:US-8618311-B2
优先权日:2005-06-15
标题:Synthetic processes for the preparation of aminocyclohexyl ether compounds
发明人：JUNG GRACE; YEE JAMES GEE KEN; CHOU DOUG TA HUNG; PLOUVIER BERTRAND M C
权利人:JUNG GRACE; YEE JAMES GEE KEN; CHOU DOUG TA HUNG; PLOUVIER BERTRAND M C; CARDIOME PHARMA CORP
摘要:This invention is directed to stereoselective synthesis of compounds of formula (I) or formula (II): n nor a pharmaceutically acceptable salt, ester, amide, complex, chelate, clathrate, solvate, polymorph, stereoisomer, metabolite or prodrug thereof; wherein R 3 , R 4 and R 5 are defined herein. Compounds of formula (I) and formula (II) are known to be useful in treating arrhythmias.

专利号:US-2007191516-A1
优先权日:2004-03-15
标题 :Process for the synthesis of amine ethers
发明人：FREY MARKUS; RAST VALERIE; BRAIG ADALBERT; KRAMER ANDREAS
权利人:FREY MARKUS; RAST VALERIE; BRAIG ADALBERT; KRAMER ANDREAS
摘要:A process for the preparation of a sterically hindered amine ether which comprises reacting a corresponding sterically hindered aminoxide with a C 5 -C 18 alk-1-ene in the presence of an organic hydroperoxide and optionally hydrogenating the resulting product as well as the product mixtures obtained therewith and their use as stabilizers and flame retardants.

专利号:US-7402675-B2
优先权日:2000-05-26
标题 :Process for the synthesis of amine ethers from secondary amino oxides
发明人：HAFNER ANDREAS; KIRNER HANS JUERG; SCHWARZENBACH FRANZ; VAN DER SCHAAF PAUL ADRIAAN; NESVADBA PETER
权利人:CIBA SC HOLDING AG
摘要:An amine ether of formula A n nwherein a is 1 or 2; and when a is 1, E is E′; when a is 2, E is L;n E′ is C 1 -C 36 alkyl; C 3 -C 18 alkenyl; C 2 -C 18 alkinyl; C 5 -C 18 cycloalkyl; C 5 -C 18 cycloalkenyl; a radical of a saturated or unsaturated aliphatic bicyclic or tricyclic hydrocarbon of 7 to 12 carbon atoms; C 2 -C 7 alkyl or C 3 -C 7 alkenyl substituted by halogen; C 7 -C 15 aralkyl or C 7 -C 15 aralkyl substituted by C 1 -C 4 alkyl or phenyl; or E′ is a radical of formula (VII) as explained in claim 1; T′ is tertiary C 4 -C 18 alkyl or phenyl, each of which are unsubstituted or substituted by halogen, OH, COOR 21 or C(O)—R 22 ; or T′ is C 5 -C 12 cycloalkyl; C 5 -C 12 cycloalkyl which is interrupted by at least one O or —NR 18 —; a polycyclic alkyl radical having 7-18 carbon atoms, or the same radical which is interrupted by at least one O or —NR 18 —; or T′ is —C(G 1 )(G 2 )-T″; or C 1 -C 18 alkyl or C 5 -C 12 cycloalkyl substituted by n n n n n n n n n n n n T″ is hydrogen, halogen, NO 2 , cyano, or is a monovalent organic radical comprising 1-50 carbon atoms; n or T″ and T′ together form a divalent organic linking group completing, together with the hindered amine nitrogen atom and the quaternary carbon atom substituted by G 1 and G 2 , an optionally substituted five- or six-membered ring structure; and all other residues are as defined in claim 1, n are obtained in good yield from the corresponding N-oxyl hindered amine precursor by reaction with a hydrocarbon E 1 -H or H-L-H in the presence of an organic hydroperoxide and a catalytic amount of copper or a copper compound. n n n n n The products of present process find utility as polymerization regulators and/or light stabilizers for organic material.