CAS: 38216-72-7; 1-Tert-Butylpiperazine

该化合物是三氯硝基苯的第三代主要衍生物,其特征是氮原子中存在一个散装的三丁基甲基苯组,这一结构特征增加了其消毒障碍,使其成为有机合成,特别是制药和农用化学品开发中的宝贵中间体,在各种条件下,其高纯度和稳定性确保了诸如通灵,杂交和催化工艺中作为离子体的一致性能. 化合物界定的分子结构也有助于对复杂的合成路径进行精确控制,有助于其在研究和工业应用中的实用性. 建议妥善处理和储存以保持其完整性.

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110469-59-5 894802-57-4 4318-42-7

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CAS号61014-95-7 4-tert-butyl-pi... | CAS号61014-96-8 3-(2-tert-butyl...

合成工艺路线路线简述

    📜1-(Tert.Butyl)-4-(Ethoxycarbonyl)Piperazin置于氢氧化钾,水体系中,用 乙醇 作为反应溶剂,化学反应 12.0H,以82%的收率获得产物n-叔丁基哌嗪
    参考文献: Diaryl Urea Derivatives In The Treatment Of Protein Kinase Dependent Diseases[fr] Derives De Diaryluree Utilises En Traitement De Maladies Dependant De Proteines Kinases
    标题: Diaryl Urea Derivatives In The Treatment Of Protein Kinase Dependent Diseases[fr] Derives De Diaryluree Utilises En Traitement De Maladies Dependant De Proteines Kinases

    海关参考信息

    专利信息


    专利号:US-8138346-B2
    优先权日:2006-08-16
    标题 :Method for synthesis of 8-alkoxy-9H-isothiazolo[5,4-B]quinoline-3,4-diones
    发明人:BRADBURY BARTON JAMES; WILES JASON ALLAN; HASHIMOTO AKIHIRO; WANG QIUPING; LUCIEN EDLAINE; PAIS GODWIN; KIM HA YOUNG
    权利人:BRADBURY BARTON JAMES; WILES JASON ALLAN; HASHIMOTO AKIHIRO; WANG QIUPING; LUCIEN EDLAINE; PAIS GODWIN; KIM HA YOUNG; ACHILLION PHARMACEUTICALS INC
    摘要:The present invention provides process for synthesis of 8-methoxy-9H-isothiazolo[5,4-b]quinoline-3,4-diones and 8A,9-dihydro-4aH-isothiazolo[5,4-b]quinoline-3,4-diones of the Formula A. n nThe substituents R, R 5 , R 6 , R 7 , R 8 and R 9 are defined herein. The invention also provides novel synthetic intermediates useful in the synthesis of 8-methoxy-9H-isothiazolo[5,4-b]quinoline-3,4-diones and 8A,9-dihydro-4aH-isothiazolo[5,4-b]quinoline-3,4-diones.

    专利号:US-11779912-B2
    优先权日:2016-10-19
    标题 :Synthesis and characterization of Ru alkylidene complexes
    发明人:JOHNS ADAM M; HERRON JESSICA R; PEDERSON RICHARD L; FIAMENGO BRYAN A; BEERMAN JENNIFER A; LIN TZU-PIN; CHU CRYSTAL K; GRUBBS ROBERT H
    权利人:UMICORE AG & CO KG; CALIFORNIA INST OF TECHN
    摘要:This invention relates generally to olefin metathesis catalyst compounds, to the preparation of such compounds, compositions comprising such compounds, methods of using such compounds, articles of manufacture comprising such compounds, and the use of such compounds in the metathesis of olefins and olefin compounds. The invention has utility in the fields of catalysts, organic synthesis, polymer chemistry, and industrial and fine chemicals industry.

    专利号:US-9951096-B2
    优先权日:2008-08-22
    标 题 :Catalysts and methods for polymer synthesis
    发明人:ALLEN SCOTT D; CHERIAN ANNA E; SIMONEAU CHRIS A; FARMER JAY J; COATES GEOFFREY W; GRIDNEV ALEXEI; LAPOINTE ROBERT E
    权利人:SAUDI ARAMCO TECH CO
    摘要:The present invention provides unimolecular metal complexes having increased activity in the copolymerization of carbon dioxide and epoxides. Also provided are methods of using such metal complexes in the synthesis of polymers. According to one aspect, the present invention provides metal complexes comprising an activating species with co-catalytic activity tethered to a multidentate ligand that is coordinated to the active metal center of the complex.

    专利号:US-9856349-B2
    优先权日:2010-09-14
    标 题:Catalysts and methods for polymer synthesis
    发明人:FARMER JAY J
    权利人:SAUDI ARAMCO TECH CO
    摘要:The present invention provides bimetallic complexes having increased activity in the copolymerization of carbon dioxide and epoxides. Also provided are methods of using such metal complexes in the synthesis of polymers. According to one aspect, the present invention provides metal complexes comprising an activating species with co-catalytic activity tethered to a multidentate ligand that is coordinated to one or more active metal centers of the complex.

    专利号:US-11718596-B2
    优先权日:2014-03-19
    标题 :Amyloid targeting agents and methods of using the same
    发明人:YANG JERRY; THEODORAKIS EMMANUEL A; SARRAF STELLA
    权利人:UNIV CALIFORNIA; AMYDIS INC
    摘要:Provided herein is the design and synthesis of novel molecular rotor fluorophores useful for detection of amyloid or amyloid like proteins. The fluorophores are designed to exhibit enhanced fluorescence emission upon associating with amyloid or amyloid like proteins as compared to unbound compound. Also disclosed herein are methods for treating diseases associated with amyloid or amyloid like proteins.

    专利号:US-11708320-B2
    优先权日:2018-06-29
    标 题:Environmentally-friendly hydroazidation of olefins
    发明人:XU HAO
    权利人:UNIV GEORGIA STATE RES FOUND
    摘要:The present invention provides processes for the synthesis of organic azides, intermediates for the production thereof, and compositions related thereto.

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