CAS: 371917-17-8; (1-(Trifluoromethyl)Cyclopropyl)Methanol
该化合物是一种氟化环丙烷衍生物,其特征是三氟甲基和氢氧化甲基功能组,该化合物在合成化学中因其受天体限制的环丙烷环和三氟甲基组的电子提取特性而具有价值,这些特性可增强核生殖性或致命性变异的再活性.氢氧化甲基混合物为进一步衍生提供了处理器,使它成为制药和农用化学应用的多用途中间体.其结构僵硬性和氟素含量可能有助于在药物设计中改善代谢稳定性和生物利用率.由于对氧化或湿度的潜在敏感性,该化合物通常在不热条件下处理.
相似化合物
277756-46-4 865833-72-3 139229-57-5物理性质
MSDS等安全信息
欧盟法规
C&L通报上下游产品
CAS号277756-46-4 1-三氟甲基环丙烷-1-羧酸 | CAS号208242-25-5 1-三氟甲基环丙烷-1-羧酸甲酯合成工艺路线路线简述
📜1-三氟甲基环丙烷-1-羧酸置于lithium Aluminium Tetrahydride体系中,用 四氢呋喃 用作溶剂,化学反应生成(1-三氟甲基-环丙基)-甲醇
参考文献: Inhibitors Of Cysteine Proteases And Methods Of Use Thereof[fr] Inhibiteurs De Cystéine Protéases Et Leurs Méthodes D'Utilisation
标题: Inhibitors Of Cysteine Proteases And Methods Of Use Thereof[fr] Inhibiteurs De Cystéine Protéases Et Leurs Méthodes D'Utilisation
摘要:本公开提供了具有腈基弹头的化合物及其在治疗医学疾病或疾病中的应用,例如病毒感染.提供了含有腈基弹头的各种化合物的制药组合物和制备方法.这些化合物被认为能够抑制蛋白酶,例如3C,Cl-或3Cl样蛋白酶.
海关参考信息
- 2905121000-正丙醇
2905141000-异丁醇
2903399090-其他无环烃卤化衍生物 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-2008176865-A1
优先权日:2005-06-15
标 题:Substituted arylpyrazoles
发明人：BILLEN DENIS; BOYLE JESSICA; CRITCHER DOUGLAS JAMES; GETHIN DAVID MORRIS; HALL KIM THOMAS; KYNE GRAHAM MICHAEL
权利人:PFIZER LTD
摘要:This invention relates to a range of 1-aryl-4-cyclopropylpyrazoles in which the cyclopropyl ring is substituted at the angular position, and pharmaceutically acceptable salts and solvates thereof, to compositions comprising such compounds, processes to their synthesis and their use as parasiticides.
专利号:US-7968584-B2
优先权日:2005-06-15
标 题:Substituted arylpyrazoles
发明人：BILLEN DENIS; BOYLE JESSICA; CRITCHER DOUGLAS JAMES; GETHIN DAVID MORRIS; HALL KIM THOMAS; KYNE GRAHAM MICHAEL
权利人:PFIZER; PFIZER PROD INC
摘要:This invention relates to a range of 1-aryl-4-cyclopropylpyrazoles in which the cyclopropyl ring is substituted at the angular position, and pharmaceutically acceptable salts and solvates thereof, to compositions comprising such compounds, processes to their synthesis and their use as parasiticides.
专利号:WO-2006134459-A1
优先权日:2005-06-15
标题 :Substituted arylpyrazoles
发明人：CRITCHER DOUGLAS JAMES; KYNE GRAHAM MICHAEL
权利人:PFIZER LTD; CRITCHER DOUGLAS JAMES; KYNE GRAHAM MICHAEL
摘要:This invention relates to a range of C4 substituted aryl pyrazoles of Formula (I) including those 1-arylpyrazoles in which the 4-position is substituted with an acyclic substituent, a cycloalkyl ring structure or heterocyclic ring structure and which compounds are optionally further substituted at the position a to the pyrazole ring, and pharmaceutically acceptable salts and solvates thereof, to compositions comprising such compounds, processes to their synthesis and their use as parasiticides.
专利号:US-7645786-B2
优先权日:2005-06-15
标题:Substituted arylpyrazoles
发明人：BILLEN DENIS; BOYLE JESSICA; CRITCHER DOUGLAS JAMES; GETHIN DAVID MORRIS; HALL KIM THOMAS; KYNE GRAHAM MICHAEL
权利人:PFIZER
摘要:This invention relates to a range of 1-aryl-4-cyclopropylpyrazoles in which the cyclopropyl ring is substituted at the angular position, and pharmaceutically acceptable salts and solvates thereof, to compositions comprising such compounds, processes to their synthesis and their use as parasiticides.
