CAS: 3393-64-4; 4-Hydroxy-3-Methyl-2-Butanone

该化合物是带有羟基功能组的氯酮衍生物,具有碳基和酒精反应性,该化合物是有机合成的多用途中间体,特别是在香味,口味和药品的生产中.其双功能结构允许选择性修改,使其对构建复杂分子很有价值.氢氧基组会增加极溶剂中的溶性,促进水分或混合阶段系统的反应.它有一个固定的立体中心,也可用于手工业合成.它在温和条件下的稳定性以及与普通试剂的兼容性进一步强调了其在精细化学应用中的效用.

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17094-21-2 609-14-3 590-90-9

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合成工艺路线路线简述

    📜2-甲基-1-丁烯-3-酮置于硫酸体系中,化学反应生成 4-羟基-3-甲基-2-丁酮
    参考文献:508. 2-甲基丁-2-烯亚硝基氯化物及其衍生物
    标题:508. 2-甲基丁-2-烯亚硝基氯化物及其衍生物
    摘要:
    DOI:10.1039/jr9560002587

    海关参考信息

    专利信息


    专利号:US-7960589-B2
    优先权日:2006-09-06
    标 题:Synthesis of sphingosines and their derivatives
    发明人:YANG HAO; LIEBESKIND LANNY S
    权利人:UNIV EMORY
    摘要:Embodiments of the present disclosure provide for methods of making sphingosines and derivatives thereof, and the like.

    专利号:US-2004053999-A1
    优先权日:1997-09-17
    标题 :Novel compounds and methods for synthesis and therapy
    发明人:BISCHOFBERGER NORBERT W; DAHL TERRENCE C; HITCHCOCK MICHAEL J M; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; MILLS ROGER G; WILLIAMS MATTHEW A
    摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.

    专利号:US-6225341-B1
    优先权日:1995-02-27
    标 题:Compounds and methods for synthesis and therapy
    发明人:BISCHOFBERGER NORBERT W; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; WILLIAMS MATTHEW A
    权利人:GILEAD SCIENCES INC
    摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.

    专利号:RU-2119916-C1
    优先权日:1995-01-05
    标题:Method of synthesis of substituted 1,10-phenanthrolines

    专利号:GB-2127023-A
    优先权日:1982-09-20
    标题:Synthesis of 25-hydroxyvitamin d2 and related compounds

    专利号:GB-2142922-A
    优先权日:1982-09-20
    标题 :Steroid intermediates in the synthesis of-hydroxyvitamin d2

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    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Harrison-Marchand, A.; Chataigner, I.; Maddaluno, J., Science of Synthesis, (2005) 26, 1243.
    摘要:Firouzabadi, H.; Iranpoor, N., Science of Synthesis, (2007) 30, 532.
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