CAS: 317-46-4; 2-Fluoro-3-Nitrobenzoic Acid

上下游产品

2-氟-3-硝基苯甲酸甲酯 Methyl 2-Fluoro-3-Nitrobenzoate 946126-94-9
2-氟-3-硝基苯甲醛 2-Fluoro-3-Nitrobenzaldehyde 96516-29-9
2-氟-3-硝基甲苯 2-Fluoro-3-Nitrotoluene 437-86-5
2-氟-3-硝基苯甲腈 2-Fluoro-3-Nitrobenzonitrile 1214328-20-7
5-Nitro-2-Iodosobenzoic Acid 23330-00-9

2-甲基-6-硝基苯酚置于chromium(Vi) Oxide,氯,苯基二氯化磷,Cesium Fluoride,Potassium Hydroxide体系中,用 水,乙腈 用作溶剂,化学反应 41.0H,反应生成2-氟-3-硝基苯甲酸
参考文献:一种2-氟-3-硝基苯甲酸中间体原料的合成方法
标题:一种2-氟-3-硝基苯甲酸中间体原料的合成方法
摘要:本发明公开一种2‑氟‑3‑硝基苯甲酸中间体原料的合成方法.本发明提供了一种新颖的合成路线,能够从便宜,易得的原料快速方便地制备一种重要医药中间体.该工艺方法是从邻甲基苯酚开始,硝化反应选择性地生成关键中间体2‑甲基‑6‑硝基苯酚,羟基氯代生成2‑氯‑3‑硝基甲苯,然后通过氟代反应生成2‑氟‑3‑硝基甲苯,最后在氧化剂作用下甲基被氧化生成2‑氟‑3‑硝基苯甲酸.本工艺不仅产率高,而且也适合大规模生成.

专利信息

专利号:US-8389767-B2
优先权日:2007-09-04
标题 :Processes and compounds
发明人：STOLLER ANDRE DENIS; JUNG PIERRE JOSEPH MARCEL; GODFREY CHRISTOPHER RICHARD AYLES; MAIENFISCH PETER; ZAMBACH WERNER
权利人:STOLLER ANDRE DENIS; JUNG PIERRE JOSEPH MARCEL; GODFREY CHRISTOPHER RICHARD AYLES; MAIENFISCH PETER; ZAMBACH WERNER; SYNGENTA CROP PROTECTION LLC
摘要:The invention relates to methods of using certain compounds of formula (I), (II) and (III) in the synthesis of an insecticide intermediate of formula (IV), wherein the substituents are as defined in claim 1 , to processes for preparing these compounds, to processes which use these compounds to prepare insecticide intermediates, and to certain novel compounds of formula (II′) and (III′).

专利号:CN-119775143-A
优先权日:2024-11-29
标 题 :Synthesis method of 2-fluoro-3-nitrobenzoic acid

专利号:CN-114560774-B
优先权日:2020-11-27
标 题 :Synthesis method of 2-fluoro-3-nitrobenzoic acid

专利号:CN-117430518-A
优先权日:2023-10-24
标题:Synthesis method and insecticide of bromiflufenamide