CAS: 26776-70-5; 1,3-Dihydroxypropan-2-One Dimer

相似化合物

18664-32-9 96-26-4 6946-10-7

上下游产品

pyridine Glyceraldehyde formaldehyd D-glucose acetaldehyde methylammonium carbonate LACTIC ACID 1,3-bis(triphenylmethoxy)-2-propanone

专利信息

专利号:US-6593347-B2
优先权日:1998-10-30
标题 :Nitrosated and nitrosylated nonsteroidal antiinflammatory compounds, compositions and methods of use
发明人：BANDARAGE UPUL K; DONG QING; FANG XINQIN; GARVEY DAVID S; MERCER GREGORY J; RICHARDSON STEWART K; SCHROEDER JOSEPH D; WANG TIANSHENG
权利人:NITROMED INC
摘要:The present invention describes novel nitrosated and/or nitrosylated nonsteroidal antiinflammatory compounds, and novel compositions comprising at least one nitrosated and/or nitrosylated nonsteroidal antiinflammatory compound, and, optionally, at least one compound that donates, transfers or releases nitric oxide, elevates endogenous levels of endothelium-derived relaxing factor, stimulates endogenous synthesis of nitric oxide or is a substrate for nitric oxide synthase. The present invention also provides methods for treating, preventing and/or reducing inflammation, pain, and fever; decreasing or reversing the gastrointestinal, renal and other toxicities resulting from the use of nonsteroidal antiinflammatory drugs; treating and/or preventing gastrointestinal disorders; treating inflammatory disease states and disorders; and treating and/or preventing ophthalmic diseases or disorders.

专利号:US-4313008-A
优先权日:1976-09-30
标题:Synthesis of S-3-chloro-1,2-propanediol
发明人：JONES HAYDN F
权利人:TATE & LYLE LTD
摘要:The S-enantiomer of 3-chloro-1,2-propanediol is prepared by reaction of a chlorodeoxy-D-saccharide having the partial structure. (I) to cleave the glycol, reduce the aldehyde so formed to an alcohol, and hydrolyse the alcohol under mild acidic conditions.

专利号:US-12378203-B2
优先权日:2018-11-01
标题 :Imidazole compounds, process for the synthesis and uses thereof
发明人：VERMA MAHESH KUMAR; KOMIRISHETTY KASHINATH; GANJU PARUL; PRASAD SUDHANAND; RICHHARIA ANNIE; SHETE SANKET SANJAY
权利人:AHAMMUNE BIOSCIENCES PRIVATE LTD
摘要:The present invention relates to novel pharmaceutical agents and the process of preparation thereof. The present invention discloses compounds of general formula I, and the process of their preparation. The compounds of the invention are useful in the treatment and prevention of diseases related to cellular stress mediated immune deregulation and loss of homeostasis also including autoimmune diseases, cancers, metabolic, dermatological, cardiovascular and neurodegenerative diseases.

专利号:WO-2009054887-A1
优先权日:2007-10-22
标 题:Process for preparing an anti-hypercholesterolemic compound
发明人：LIMANTO JOHN; TAN LUSHI; DREHER SPENCER D; DORNER BENJAMIN T; YOSHIKAWA NAOKI; KRSKA SHANE W
权利人:MERCK & CO INC; LIMANTO JOHN; TAN LUSHI; DREHER SPENCER D; DORNER BENJAMIN T; YOSHIKAWA NAOKI; KRSKA SHANE W
摘要:The present invention relates to a process for preparing inhibitors of cholesterol absorption of Formula II: II and the pharmaceutically acceptable salts and esters thereof, employing a metal-catalyzed dynamic kinetic resolution (DKR) asymmetric transfer hydrogenation (ATH) reaction of racemic acyclic ß-ketoamide bearing a-substituted aliphatic side chain (Intermediate A) and subsequent cyclization of the resulting b-hydroxyamide product (Intermediate B), followed by a synthesis involving two consecutive cross-coupling reactions.

专利号:US-6040335-A
优先权日:1995-10-17
标题 :Therapeutics for thrombocytopenia
发明人：SAITOH MASAYUKI; KITAJIMA YASUO; IWASAWA NORIO; MIURA KENJU; HARUYAMA MUNETADA; HASHINO JUNKO
权利人:SUNTORY LTD
摘要:Compounds represented by the general formula (I) or pharmacologically acceptable salts thereof: ##STR1## (where R is a group --NHCHR 1 R 2 , --N(CHR 1 R 2 ) 2 , --N(CHR 1 R 2 )CHR 3 R 4 , --N + (CHR 1 R 2 ) 3 , --N + (CHR 1 R 2 ) 2 CHR 3 R 4 or --N + (CHR 1 R 2 )(CHR 3 R 4 )CHR 5 R 6 (where R 1 , R 2 , R 3 , R 4 , R 5 and R 6 , which may be the same or different, are each a hydrogen atom, an alkyl group, an alkenyl group, an aryl group or an aralkyl group, or an alkyl, alkenyl, aryl or aralkyl group which is substituted by at least one substituent selected from the group consisting of a halogen atom, a hydroxyl group, a lower alkoxy group, a lower alkylacyloxy group, a lower alkylacyl group, a lower alkoxycarbonyl group, a nitro group, a cyano group and a heterocyclic group, with CHR 1 R 2 , CHR 3 R 4 or CHR 5 R 6 optionally forming a cyclic alkyl group, provided that when R is --N(CHR 1 R 2 )CHR 3 R 4 , --N + (CHR 1 R 2 ) 2 CHR 3 R 4 or --N + (CHR 1 R 2 )(CHR 3 R 4 )CHR 5 R 6 , CHR 1 R 2 , CHR 3 R 4 and CHR 5 R 6 are different groups); therapeutics for thrombocytopenia containing them as an effective ingredient; as well as intermediates for their synthesis and processes for producing them.

专利号:CN-117362237-A
优先权日:2023-10-10
标 题:Synthesis method of etomidate