CAS: 16563-14-7; 4-Oxotetrahydrothiophene-3-Carbonitrile

该化合物是一种七环化合物,在4个和3个位置分别有一个配有氯酮(oxo)和(conitrile)功能组的硫lane环,这种结构赋予适合有机合成应用的再活性,特别是作为生产药品,农用化学品和特殊化学品的多用途中间体,它具有可操作性,而高纯度则能确保合成工作流程的一贯性.

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1003-04-9 2689-68-1 13679-85-1

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ECHA物质C&L通报

上下游产品

CAS号2365-48-2 巯基乙酸甲酯 | CAS号107-13-1 丙烯腈 | CAS号95469-88-8 2-苯基-2,6-二氢-4H-... | CAS号61325-08-4 4-(4-chloro-2-n... | CAS号61325-11-9 4-(4-methylsulf... | CAS号61325-28-8 4-(2-aminoanili... | CAS号61325-31-3 4-(2-amino-4-ch...

合成工艺路线路线简述

    📜巯基乙酸甲酯,丙烯腈置于sodium Methylate体系中,用 甲醇 用作溶剂,化学反应 1.0H,以50%的收率获得4-氰基-3-四氢噻吩酮
    参考文献:A New Simple Synthesis Of α-Substituted Acrylonitriles
    标题:A New Simple Synthesis Of α-Substituted Acrylonitriles
    摘要:描述了基于利用 4-Cyano-3-Ketothiolane 烯醇阴离子 (3) 作为 α-丙烯腈阴离子 (1) 的合成等价物的有效制备α-取代丙烯腈 6 的方法.
    Doi:10.1055/s-1985-31407

    海关参考信息

    专利信息


    专利号:US-6545033-B1
    优先权日:1999-10-06
    标 题:Fused 1-(2,6-dichloro-4-trifluoromethylphenyl)-pyrazoles, the synthesis thereof and the use thereof as pesticides
    发明人:DHANOA DALJIT S; MEEGALLA SANATH; SOLL RICHARD M; DOLLER DARIO; SHA DEYOU; LIU RUIPING; SILVER GARY; LEE YU-KAI
    权利人:DIMENSIONAL PHARM INC
    摘要:The present invention is directed to novel pyrazole derivatives and their use as pesticidal agents. The pyrazole derivatives have Formula I:or a salt thereof, whereR1 is amino, hydrogen, alkyl, hydroxy, halo, alkoxy, alkylamino, dialkylamino, alkylthio, alkylsulfinyl, alkylsulfonyl, trifluoroalkylsulfinyl, trifluoroalkylsulfonyl, hydroxy, amino, trifluoromethyl, acetylamino, -OSO2R2, -OS(O)R2, -OC(O)R2, -OC(O)NHR2, or -NHC(O)NHR2 where R2 is C1-4 alkyl or optionally substituted aryl;X, Y and Z are each independently (CH)n, (CR3R4)n, S, S(O), or SO2, wherein n is 1-2, R3 and R4 are defined herein;Q is N or C-R6, wherein R6 is fluoro, chloro, bromo, or iodo;R5 is halo, C1-C6 alkyl, C1-C4 alkenyl, C1-C4 alkoxy, C1-C4 alkylamino, C1-C4 dialkylamino, C1-C4 alkylthio, C1-C4 alkylsulfinyl, C1-C4 alkylsulfonyl, C1-C4 trifluoroalkylsulfinyl, C1-C4 trifluoroalkylsulfonyl, hydroxy, amino, or trifluoromethyl; andwith the proviso that only one of X, Y and Z can be S, S(O) or SO2.

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    合成参考文献


    摘要:Sato, R.; Kimura, T., Science of Synthesis, (2008) 39, 745.
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