CAS: 112245-13-3; (S)-2-Amino-3,3-Dimethylbutan-1-Ol

相似化合物

3907-02-6 112245-09-7 153645-26-2

上下游产品

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(S)-3,3-Dimethyl-2-((S)-1-Phenyl-Ethylamino)-Butan-1-Ol置于氢气体系中,化学反应生成L-叔亮氨醇
参考文献:Synthesis Of 1,2-Aminoalcohols By Ti(Iv)-Catalyzed Photohydroxymethylation Of Chiral Aldimines
标题:Synthesis Of 1,2-Aminoalcohols By Ti(Iv)-Catalyzed Photohydroxymethylation Of Chiral Aldimines
摘要:The N-(Alpha-Phenylethyl) Alkylated Aldimines 3A-C Are Conveniently Hydroxymethylated With Moderate Diastereoselectivities By Means Of Irradiation In Methanolic Solution In The Presence Of Titanium(Iv)Chloride. (C) 1998 Elsevier Science Ltd. All Rights Reserved.
Doi:10.1016/s0040-4039(98)00339-6

专利信息

专利号:US-10040752-B2
优先权日:2015-08-24
标 题 :Synthesis of levomethadone hydrochloride or dextromethadone hydrochloride and methods for use thereof
发明人：MKRTCHYAN GNEL; YAO QINGWEI
权利人:CODY LABORATORIES INC
摘要:Highly efficient methods for synthesis of levomethadone hydrochloride or dextromethadone hydrochloride are provided starting from D-alanine, or L-alanine, respectively, with retention of configuration. Methods for treating a subject are provided comprising administering a composition comprising an effective amount of levomethadone hydrochloride having not more than 10 ppm dextromethadone.

专利号:WO-2024054881-A1
优先权日:2022-09-07
标题:Ligand-enabled scalable c-h hydroxylation of benzoic and phenylacetic acids at room temperature
发明人：YU JIN-QUAN; LI ZHEN; PARK HAN
权利人:SCRIPPS RESEARCH INST
摘要:The application discloses industry scalable methods of using bifunctional bidentate pyridone-carboxylic acid ligands, such as 2-methyl-2-(6-oxo-1,6-dihydropyridin-2-yl)propanoic acid, that enable room-temperature Pd-catalyzed C-H hydroxylation of a broad range of benzoic and phenylacetic acids with an industry-compatible oxidant, aqueous hydrogen peroxide, at room temperature. Further disclosed are methods of derivatization of the resulting hydroxylation products, synthesis of polyfluorinated natural products coumestan or pterocarpene from phenol building blocks, and hydroxylation of ibuprofen using this methodology,

专利号:WO-2024121335-A1
优先权日:2022-12-07
标题:Synthesis of sulfoximine compounds having a stereogenic sulfur atom
发明人：WILLIAMS SIMON; SMITS HELMARS
权利人:SYNGENTA CROP PROTECTION AG
摘要:A process for the preparation of compound of formula (I) which process comprises: (A) stereoselectively oxidizing a sulfanyl compound of formula (II) followed by (B) stereospecific imination of a sulfinyl compound of formula (III) is disclosed wherein the substituents are as defined in claim 1.

专利号:WO-2024200180-A1
优先权日:2023-03-29
标题 :Novel l-thyroxine radioiodine label and process for production thereof
发明人：DREWES BIRTE; BIER DIRK; HOLSCHBACH MARCUS; HUMPERT SWEN; SCHNEIDER DANIELA; NEUMAIER BERND
权利人:FORSCHUNGSZENTRUM JUELICH GMBH
摘要:The present invention relates to a multistage synthesis process proceeding from 3,5-diiodo-L-thyronine for synthesis of an L-thyroxine radiolabelled in the 3 position on the inner ring. The present invention further relates to specific intermediates in the synthesis process of the invention, to the radiolabels obtainable and to the use of the radiolabels in nuclear-medical imaging methods and in in vitro and ex vivo applications.

专利号:WO-2025136842-A1
优先权日:2023-12-19
标题 :Process for preparing n-aminoalkylated tryptophan compounds
发明人：CO SARAH S; DALBY STEPHEN M; JOHNSON KEYWAN ALEXANDER; KLAPARS ARTIS; KUETHE JEFFREY T; PETERS BYRON KENNEDY; SIROTA ERIC; WRIGHT TIMOTHY JAMES; XIAO KAIJIONG
权利人:MERCK SHARP & DOHME LLC
摘要:The present invention relates to processes useful in the synthesis of aminohexyl compounds, such as a compound of Formula I or a salt, hydrate and/or solvate thereof, as well as methods for the preparing a compound of Formula I and intermediates used to make a compound of Formula I. The present invention presents a novel method for the selective alkylation of tryptophan analogues, eliminating the need for protecting groups and advancing the field of tryptophan analogue synthesis.

专利号:US-7468375-B2
优先权日:2004-04-26
标题:Inhibitors of the HIV integrase enzyme
发明人：DRESS KLAUS RUPRECHT; HU QIYUE; JOHNSON TED WILLIAM; PLEWE MICHAEL BRUNO; TANIS STEVEN PAUL; WANG HAI; YANG ANLE; YIN CHUNFENG; ZHANG JUNHU
权利人:PFIZER
摘要:The present invention is directed to compounds of formula (I), and pharmaceutically acceptable salts and solvates thereof, their synthesis, and their use as modulators or inhibitors of the human immunodeficiency virus (“HIVâ€?) integrase enzyme.