CAS: 91702-88-4; 5-(Methylamino)Nicotinic Acid

该化合物是其环状结构的有机化合物,其特点是有六人组成的芳香环,内含一个氮原子;该化合物的特点是一个碳酸性功能组(-COOH)和一个附于环状的甲基氨基组(-NH(CH3-3)2),具体地说,分别是5和3个位置;这些功能组的存在使分子具有酸性和基本特性,使其有可能在各种化学反应和应用中发挥作用;该化合物一般是室温固态的,由于存在碳酸组,极溶剂中可能出现溶性;该化合物还可能参与氢的结合,影响其与其他物质的再活性和相互作用;该化合物的独特结构允许在制药,农业化学品或作为有机合成的构件块中的潜在应用.但是,熔点,沸点和溶性等具体特性可以不同,并且应当从可靠的化学数据库或文献中参考准确的信息.

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相似化合物

337904-92-4 24242-19-1 36052-25-2

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5-bromo-3-pyridinecarboxylic acid 3,5-dibromopyridine 3-(methylamino)-5-bromopyridine methyl 5-(methylamino)pyridine-3-carboxylate

合成工艺路线路线简述

  • 91702-86-2 = 91702-88-4
    反应条件:1.1 Reagents: Lithium Hydroxide,Monohydrate Solvents: Methanol,Water; 17 H,Rt1.2 Reagents: Hydrochloric Acid Solvents: Water; 15 Min,Rt
    标题:Convenient Synthesis Of Aminopyridinecarboxylic Acids
    作者:Okamoto,Iwao; Et Al
    参考文献:Heterocycles 日期:2011 卷标:83(10) 页码:2343-2352]

    = 91702-88-4 [标题:Reaction Conditions
    标题:Aminopyridinecarboxylic Acid Derivatives And Their Use
    参考文献:European Patent Organization]

    873383-06-3 = 91702-88-4
    反应条件:1.1 Reagents: Triethylamine Catalysts: (Sp-4-2)-[1,1′-[1,1′-Binaphthalene]-2,2′-Diylbis[1,1-Diphenylphosphine-Kp]]Dichl... Solvents: Methanol; 23 H,0.4 Mpa,100 °C2.1 Reagents: Lithium Hydroxide,Monohydrate Solvents: Methanol,Water; 17 H,Rt2.2 Reagents: Hydrochloric Acid Solvents: Water; 15 Min,Rt
    标题:Convenient Synthesis Of Aminopyridinecarboxylic Acids
    作者:Okamoto,Iwao; Et Al
    参考文献:Heterocycles 日期:2011 卷标:83(10) 页码:2343-2352]

    625-92-3 = 91702-88-4
    反应条件:1.1 Solvents: Water; 46 H,190 °C2.1 Reagents: Triethylamine Catalysts: (Sp-4-2)-[1,1′-[1,1′-Binaphthalene]-2,2′-Diylbis[1,1-Diphenylphosphine-Kp]]Dichl... Solvents: Methanol; 23 H,0.4 Mpa,100 °C3.1 Reagents: Lithium Hydroxide,Monohydrate Solvents: Methanol,Water; 17 H,Rt3.2 Reagents: Hydrochloric Acid Solvents: Water; 15 Min,Rt
    标题:Convenient Synthesis Of Aminopyridinecarboxylic Acids
    作者:Okamoto,Iwao; Et Al
    参考文献:Heterocycles 日期:2011 卷标:83(10) 页码:2343-2352
📜3,5-二溴吡啶置于二氯[2,2'-二(二苯基磷)-1,1'-联萘]钯(II),Lithium Hydroxide Monohydrate,三乙胺体系中,用 甲醇,水 作为反应溶剂,20.0~190.0 °C,400.01 Kpa 条件下,反应 86.0H,反应生成 5-甲氨基烟酸
参考文献:Convenient Synthesis Of Aminopyridinecarboxylic Acids
标题:Convenient Synthesis Of Aminopyridinecarboxylic Acids
摘要:6-(Alkylamino)Pyridine-2-Carboxylic Acids And 5-(Alkylamino)Pyridine-3-Carboxylic Acids Were Conveniently Synthesized From Dibromopyridine In Satisfactory Yields.
DOI:10.3987/com-11-12290

海关参考信息

专利信息


专利号:US-2014315720-A1
优先权日:2012-10-24
标 题 :Polysaccharide ester microspheres and methods and articles relating thereto
发明人:FALLON DENIS G; GARRETT THOMAS S; KIZER LAWTON E; ZAZZARA KAREN L; COMBS MICHAEL T; JOHNSON RICHARD K; DEHART GARY
权利人:CELANESE ACETATE LLC
摘要:A method for producing a polysaccharide ester microsphere may include forming a polysaccharide ester product from a polysaccharide synthesis, wherein the polysaccharide ester product comprises a polysaccharide ester and a solvent; diluting the polysaccharide ester product, thereby yielding a polysaccharide ester dope; and forming a plurality of polysaccharide ester microspheres from the polysaccharide ester dope. Suitable polysaccharides may include, but are not limited to, starch, cellulose, hemicellulose, algenates, chitosan, and any combination thereof. Esters thereof may be organic esters (e.g., acetate and the like), inorganic esters (e.g., sulfonates and the like), or combinations thereof. Further, the solids conent of the polysaccharide ester dope, in some instances, may be greater than about 16 wt %.

专利号:IT-8224576-A1
优先权日:1982-12-03
标题 :New derivatives of aminopyridincarboxylic acids, their synthesis methods and pharmaceutical compositions containing them

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合成参考文献


参考文献:10.1177/1087057116635503
摘要:Voter AF, Manthei KA, Keck JL. A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway. J Biomol Screen. 2016 Jul;21(6):626–33.
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