CAS: 7635-11-2; L-Allose

该化合物是一种稀有的糖,是D-Allose的缩影,被归类为Aldohexose.它是分子式C6H12O6的单沙化物,其分子式为C6-H12A6,由6个碳原子,12个氢原子和6个氧原子组成.L-Allose的特点是口味甜,尽管它比葡萄糖和浮糖等普通糖糖糖甜,但它比葡萄油糖和软糖等常见糖糖更甜.它溶于水中,适合食品和制药工业的各种应用.该物质具有潜在的健康利益,包括它在代谢工艺中的作用及其影响胰岛素敏感性的能力.LAllse在某些水果中可以找到微量,并且对低糖分指数感兴趣,使它成为糖尿病饮食中替代糖的候选物.它独特的结构特性,包括氢氧基化合物的特殊安排,有助于其独特的生物化学行为.相对不那么常见的糖仍在研究中,因为其潜在的用途和营养和健康方面的好处.

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921-60-8 3458-28-4 15572-79-9

上下游产品

L-mannonic γ-lactone mannitol para-xylene watero-nitrothiophenol p-benzosemiquinone radical anion O-acetyl-glucopyranosyl bromidetetra-O-acetyl-glucopyranosyl bromide D-glucoheptonic acid

合成工艺路线路线简述

    📜L-铝离子-1,4-内酯置于sodium Amalgam,硫酸,水体系中,化学反应生成 阿罗糖
    参考文献:The Preparation Of Two New Crystalline Aldohexoses,L-Allose And L-Altrose,From L-Ribose By The Cyanohydrin Reaction1,2,3
    标题:The Preparation Of Two New Crystalline Aldohexoses,L-Allose And L-Altrose,From L-Ribose By The Cyanohydrin Reaction1,2,3
    摘要:
    DOI:10.1021/ja01320A048

    海关参考信息

    专利信息


    专利号:US-2023212216-A1
    优先权日:2019-12-20
    标 题:Synthesis of lactone derivatives and their use in the modification of proteins
    发明人:MORRIS ALEXANDER REDFERN; SUTOV GRIGORIJ; BRUNE KARL DIETRICH
    权利人:GENIE BIOTECH UK LTD
    摘要:Site-specific modifications of proteins are desirable in biotechnological applications such as biopharmaceuticals, immunotherapy, vaccines, and are useful in chemical biology. Gluconoylation is a non-enzymatic, covalent, post-translational modification commonly observed on N-terminal His-Tags bearing proteins. We synthesized glucono-1,5-lactone derivatives, including azido variants for selective acylation. High yield acylation is achieved by simply mixing derivatives with target protein amidst diverse conditions of temperatures, aqueous buffers, excipients, or complex cell lysate.

    专利号:US-2016122450-A1
    优先权日:2013-05-08
    标题:Synthesis of a substituted furan
    发明人:ZHANG YUGEN; TEONG SIEW PING; YI GUANGSHUN
    权利人:AGENCY SCIENCE TECH & RES
    摘要:The present invention provides a polymer comprising an aliphatic backbone having a plurality of aromatic rings bonded thereon, said plurality of aromatic rings comprising a first aromatic ring type that has an alkyl halide group substitution on the aromatic ring and a second aromatic ring type that has an optionally substituted ammonium halide group substitution on the aromatic ring. The present invention also provides a method for making an optionally substituted furan, the method comprising the step of subjecting a sugar to a dehydration reaction in the presence of a catalyst comprising said polymer.

    专利号:US-5627270-A
    优先权日:1991-12-13
    标题:Glycosylated steroid derivatives for transport across biological membranes and process for making and using same
    发明人:KAHNE DANIEL E; KAHNE SUZANNE W; SOFIA MICHAEL J; HATZENBUHLER NICOLE T
    权利人:UNIV PRINCETON; TRANSCELL TECHNOLOGIES INC
    摘要:Novel glycosylated steroid derivatives for facilitating the transport of compounds across biological membranes, either in admixture or as conjugates, are disclosed. A novel process for efficient synthesis of these glycosylated steroid derivatives, using activated glycosyl sulfoxide intermediates is provided. Methods for the permeabilization of membranes and the enhancement of the activity of predetermined compounds are also provided.

    专利号:US-5693769-A
    优先权日:1991-12-13
    标 题 :Glycosylated steroid derivatives for transport across biological membranes and process for making and using same
    发明人:KAHNE DANIEL EVAN; KAHNE SUZANNE WALKER
    权利人:TRANSCELL TECHNOLOGIES INC; UNIV PRINCETON
    摘要:Novel glycosylated steroid derivatives for facilitating the transport of compounds across biological membranes, either in admixture or as conjugates, are disclosed. A novel process for efficient synthesis of these glycosylated steroid derivatives, using activated glycosyl sulfoxide intermediates is provided. Methods for the permeabilization of membranes and the enhancement of the activity of predetermined compounds are also provided.

    专利号:AU-2020409711-A1
    优先权日:2019-12-20
    标题 :Synthesis of lactone derivatives and their use in the modification of proteins

    专利号:EP-4076533-A1
    优先权日:2019-12-20
    标 题:Synthesis of lactone derivatives and their use in the modification of proteins

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    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1007/s10529-010-0224-x
    摘要:Yeom SJ, Kim BN, Park CS, Oh DK. Substrate specificity of ribose-5-phosphate isomerases from Clostridium difficile and Thermotoga maritima. Biotechnol Lett. 2010 Jun;32(6):829–35. doi: 10.1007/s10529-010-0224-x.
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