CAS: 3197-06-6; 2,2'-((2-Aminoethyl)Azanediyl)Diethanol

相似化合物

60487-26-5 140-07-8 116763-69-0

上下游产品

oxirane monoacetylaminoethylamine ethylenediamine 2,2'-iminobis[ethanol]N,N-bis-(2-hydroxy-ethyl)-N'-(2-phenyl-[4]quinolyl)-ethylenediamineN,N-bis-(2-hydroxy-ethyl)-N'-(2-phenyl-[4]quinolyl)-ethylenediamine N,N-bis(2-chloroethyl)ethylenediamine dihydr°Chloride 2-[[2-(4-Ethyl-5-methyl-2-nitro-phenylamino)-ethyl]-(2-hydroxy-ethyl)-amino]-ethanol -aethyl)-4,5-dichlor-2-nitro-anilinN-(2--aethyl)-4,5-dichlor-2-nitro-anilin

[双-(2-羟基-乙基)-氨基]-乙腈置于c46H178O41Si42,Titanium(Iv)Isopropoxide,水,Sodium Hydroxide体系中,用 甲苯 作为反应溶剂,化学反应 28.0H,以37%的收率获得产物n,N-双(2-羟乙基)乙二胺
参考文献:通过二腈还原直接获得环胺
标题:通过二腈还原直接获得环胺
摘要:1,1,3,3-四甲基二硅氧烷(tmds)和聚甲基氢硅氧烷(pmhs)与异丙醇钛(iv)结合使用时,提供了两个方便的系统,可将腈还原为相应的伯胺.通过1 H NMR研究了这两个系统的动力学,结果表明,用pmhs进行还原的速度比用tmds进行还原的速度更快.在存在br,Cc,No 2的情况下,这两个钛基体系同时还原芳族和脂肪族腈,Oh和环丙基环.在环丙基腈的情况下,观测到由于分子间还原性烷基化反应而形成的仲胺.该结果被用于还原二腈,其通过分子内还原性烷基化反应一步一步导致了氮杂环庚烷,哌啶,吡咯烷和氮杂环丁烷衍生物.
DOI:10.1016/j.Tet.2013.11.101

专利信息

专利号:WO-0140193-A1
优先权日:1999-12-03
标题:Method for the synthesis of pyrazolines
发明人：BOLDI ARMEN M
权利人:CHEMRX ADVANCED TECHNOLOGIES I; BOLDI ARMEN M
摘要:The present invention provides a method for the synthesis of compounds of Formula (I). Also claimed are novel intermediates and their methods of synthesis.

专利号:US-2002103381-A1
优先权日:2000-11-30
标 题 :Method for the synthesis of pyrazolines
发明人：BOLDI ARMEN M
摘要:The present invention provides a method for the synthesis of compounds of Formula I: n n n Also claimed are novel intermediates and their methods of synthesis.

专利号:US-4709034-A
优先权日:1986-02-14
标 题 :Process for the synthesis of hydroxyalkyl amines and hydroxyalkyl piperazines
发明人：MARSELLA JOHN A
权利人:AIR PROD & CHEM
摘要:The present invention comprises a process for the synthesis of hydroxyalkyl amines, hydroxyalkyl piperazines, or alkyl piperazines from alkylene glycols and ammonia or alkyl amines using a substantially soluble transition metal carbonyl complex catalyst precursor.

专利号:US-5414077-A
优先权日:1990-02-20
标题 :Non-nucleoside linkers for convenient attachment of labels to oligonucleotides using standard synthetic methods
发明人：LIN KUEI-YING; MATTEUCCI MARK
权利人:GILEAD SCIENCES
摘要:Pseudonucleosides and pseudonucleotides are useful in the synthesis of oligomers which contain these components as a means to derivatize the resulting oligonucleotide to useful substituents such as chelators, intercalators, or lipophilic compounds. In general, these pseudonucleotide components are of the formula: (1) wherein each Y is independently O or S; each X is independently H, PO3-2, an activated nucleotide synthesis coupling moiety, a protecting group, a nucleoside, a nucleotide or a nucleotide sequence, or comprises a solid support; F is a functional group capable of linking an additional moiety or said group already reacted to effect the binding of said additional moiety; &squ& is an organic backbone which does not contain additional F or Y-X substituents and which is either achiral even when the Y-X substituents are different, or is a single enantiomer of a chiral compound; with the proviso that at least one X is a nucleoside, nucleotide, nucleotide sequence, an activated nucleotide synthesis coupling moiety, or comprises a solid support, or F represents said functional group already reacted with an additional group. Oligonucleotides having the pseudonucleoside at the 3' terminus are particularly stable in vivo.

专利号:US-6110907-A
优先权日:1997-04-30
标题 :Synthesis of platinum complexes and uses thereof
发明人：AU-YEUNG STEVE C F; HO YEE PING; GE LIN; XIUWEN HAN; XINNING WANG; SHIWEI LU; TAO JIANG
权利人:DALIAN CHEMICAL PHYSICS INST; UNIV HONG KONG CHINESE
摘要:This invention provides novel antitumor demethylcantharidin platinum complexes. This invention also provides a composition comprising at least one of said demethylcantharidin platinum complexes and a suitable carrier. This invention provides a pharmaceutical composition comprising effective amount of at least one of the said demethylcantharidin platinum complexes and a pharmaceutically acceptable carrier. This invention provides a method of inhibiting the growth of tumorous cells comprising contacting the cells with an amount of said demethylcantharidin platinum complex effective to inhibit the growth of said tumorous cells. This invention provides a method of inhibiting the growth of tumorous cells in a subject comprising administering to the subject with an amount of the said demethylcantharidin platinum complexes effective to inhibit the growth of said tumorous cells in the subject. Finally, this invention provides methods for producing said demethylcantharidin platinum complexes.

专利号:US-4686285-A
优先权日:1984-02-10
标题:Basic azo and non-azo compounds having one or two disubstituted 1,3,5-triazine rings each of which is linked through a bridging radical to the 1-position of a pyrazole ring
发明人：PEDRAZZI REINHARD
权利人:SANDOZ LTD
摘要:(i) Metal-free compounds of the formula ##STR1## (ii) tautomers thereof, (iii) 1:1 and 1:2 metal complexes of (i) and (ii), n (iv) salts of (i), (ii), and (iii), and n (v) mixtures of (i), (ii), (iii), and (iv), n wherein the symbols are as defined in the Specification, are useful as dyes for, for example, polymers and copolymers of acrylonitrile, polyesters modified to contain acid groups, polyamides such as wool, leather, cotton, bast fibers such as hemp, flax, sisal jute, coir and straw, regenerated cellulose, glass fibers and paper (those wherein R o is other than hydrogen) or as intermediates for the synthesis of dyes.