CAS: 223580-51-6; N-(3-Chloro-4-Methylphenyl)-4-Methyl-1,2,3-Thiadiazole-5-Carboxamide

该化合物是一种化学化合物,属于硫苯衍生物类别,主要在农业化学中应用,特别是作为杀真菌剂;该化合物展示了一种针对真菌病原体的具体行动方式,使其有效保护作物免受各种疾病的危害;该物质具有独特的分子结构,其中包括一个促进其生物活动的硫苯环;该物质通常用于农业环境,其功效可能受到环境条件和应用方法等因素的影响;许多农用化学品,安全和环境影响评估对于其使用至关重要,确保它符合农业应用的监管标准;此外,了解其化学特性,例如溶性与稳定性,对于在虫害管理战略中优化其效力至关重要.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

合成工艺路线路线简述

    📜3-氯-4-甲基苯胺,4-甲基-1,2,3-噻二唑-5-羧酸置于1-羟基苯并三唑,1-(3-二甲基氨基丙基)-3-乙基碳二亚胺体系中,用 水,N,N-二甲基甲酰胺 用作溶剂,以88 %的收率获得噻酰菌胺
    参考文献:10.1021/acs.Oprd.4C00043
    标题:10.1021/acs.Oprd.4C00043
    摘要:
    Doi:10.1021/acs.Oprd.4C00043

    海关参考信息

    专利信息


    专利号:WO-2025056767-A1
    优先权日:2023-09-15
    标题 :Process for the preparation of enantiomerically enriched aliphatic amines
    发明人:BOU HAMDAN FARHAN; GODINEAU EDOUARD; SMEJKAL TOMAS; DUMEUNIER RAPHAEL; BOUSSEMGHOUNE MOHAMED ABDELOUAHAB; BLUM MATHIAS
    权利人:SYNGENTA CROP PROTECTION AG
    摘要:The present invention relates to a process for the preparation of enantiomerically enriched cyclobutylamines of formula (I) from α-tertiary cyclobutanones and reacting said enantiomerically enriched cyclobutylamines to enantiomerically enriched cyclobutylamides. Such compounds are useful intermediates in the synthesis of microbiocidal thiazole compounds.

    专利号:US-10906880-B2
    优先权日:2016-01-26
    标题:Kind of isothiazole oxime ether-containing strobilurin derivatives and its preparation methods and application
    发明人:FAN ZHIJIN; CHEN LAI; GUO XIAOFENG; ZHU YUJIE; QIAN XIAOLIN; MA LIUYONG; ZHANG NAILOU; WANG HAIXIA; ZHANG ZHIMING; XU JINGHUA; SONG YINQI
    权利人:UNIV NANKAI
    摘要:The present invention is that provided a synthesis method of a series of isothiazole oxime ether containing strobilurin derivatives IV. The present invention relates to 3,4-dichloroisothiazolyl oxime ether strobilurin derivatives, and their chemical structural formula is as shown by IV. n n n n n n n n n n The invention discloses the structural formula of the above compound, the synthesis method and the use as an insecticide, a fungicide, an anti-plant virus agent, and an agriculturally acceptable auxiliary or synergist and a commercial insecticide. The use of a fungicide, an anti-plant virus agent and an acaricide in combination for controlling agricultural, forestry, horticultural plant pests, diseases, virus diseases and preparation methods.

    专利号:US-9968097-B2
    优先权日:2012-05-30
    标题:Composition comprising a biological control agent and a fungicide selected from inhibitors of the lipid membrane synthesis, the melanine biosynthesis, the nucleic acid synthesis or the signal transduction
    发明人:WACHENDORFF-NEUMANN ULRIKE; ANDERSCH WOLFRAM; STENZEL KLAUS; SPRINGER BERND
    权利人:BAYER CROPSCIENCE AG
    摘要:The present invention relates to a composition comprising at least one biological control agent. Furthermore, the present invention relates to the use of this composition as well as a method for reducing overall damage of plants and plant parts.

    专利号:US-2007232495-A1
    优先权日:2006-03-24
    标题:Compositions and methods to add value to plant products, increasing the commercial quality, resistance to external factors and polyphenol content thereof
    发明人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
    权利人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
    摘要:The invention is related to compositions and methods that naturally protect plant tissues against ultraviolet radiation and temperature, thus giving protection against sunburn to plants, plant parts, fruits and/or flowers during their development. The invention is also related to compositions and methods to naturally improve the color of plants, plant parts, fruits and/or flowers by inducing the natural synthesis of flavonoids and anthocyanins present in plants. Likewise, the present invention is directed to improving the nutritional value of plants, plant parts, fruits and/or flowers by increasing the normal levels of polyphenolic compounds, especially flavonoids, present therein. Additionally, the present invention is related to compositions and methods that give more resistance to plants, plant parts, fruits and/or flowers against pathogens as bacteria and fungi. Finally, the present invention is related to plants, plant parts, fruits, flowers and/or propagating material treated with the compositions described in the present document.

    专利号:WO-2019218027-A1
    优先权日:2018-05-18
    标题:Core-shell particles
    发明人:MEANEY SHANE; TABOR RICHARD; FOLLINK BART
    权利人:UNIV MONASH
    摘要:The application relates to a core-shell particle having a) a cross-linked polyelectrolyte core, and b) a silica-based shell having covalently bound thereto one or more groups of formula –R–F, wherein R is an organic group and F is a functional moiety. The application also relates to a method of synthesis of a core-shell particle, the method comprising the steps of: a) providing a cross-linked polyelectrolyte core template, b) coating the core template with a silica-based shell, and c) introducing one or more groups of formula –R–F covalently bound to the silica-based shell, wherein R is an organic group and F is a functional moiety.

    专利号:WO-2021074309-A1
    优先权日:2019-10-16
    标 题:1-(3-quinolyl)-3,4-dihydroisoquinoline derivatives as fungicides for combating specific phytopathogens
    发明人:WEISS MATTHIAS; QUARANTA LAURA; BOU HAMDAN FARHAN; MAHAJAN ATUL; WILLIAMS SIMON; KILARU JAGADEESH; SEN INDIRA; BIERI STEPHANE; DIGGELMANN MARTIN
    权利人:SYNGENTA CROP PROTECTION AG
    摘要:1-(3-quinolyl)-3,4-dihydroisoquinoline derivatives of formula (I) as well as a method of combating, preventing or controlling the phytopathogens Mycosphaerella graminicola (Septoria tritici), Fusarium culmorum, Gibberella zeae (Fusarium graminearum) and Monographella nivalis (Microdochium nivale), which comprises applying to the phytopathogen, to the locus of the phytopathogen, or to a plant susceptible to attack by the phytopathogen, or to propagation material thereof, a fungicidally effective amount of a 1-(3-quinolyl)-3,4-dihydroisoquinoline derivative of formula (I). The present description discloses the synthesis of exemplary compounds, formulation examples, relevant biological data (antifungal activity against Mycosphaerella graminicola (Septoria tritici), Fusarium culmorum, Gibberella zeae (Fusarium graminearum) and Monographella nivalis (Microdochium nivale) when spayed on plants), as well as comparative data against three prior art compounds (e.g. pages 52 to 85; formulation examples; examples A1 to A3; table E; compounds E.01 to E.187; biological examples). Exemplary compounds are e.g.: 5-bromo-1-(8-fluoro-3-quinolyl)spiro[4H-isoquinoline-3,1'- cyclopropane] (example A1) 5-bromo-1-(8-fluoro-3-quinolyl)-3,3-dimethyl-4H-isoquinoline (example A2) 1-(8-fluoro-3-quinolyl)-3,3-dimethyl-4H-isoquinoline-5-carbonitrile (example A3)

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Maeda T, Ishiwari H. Tiadinil, a plant activator of systemic acquired resistance, boosts the production of herbivore-induced plant volatiles that attract the predatory mite Neoseiulus womersleyi in the tea plant Camellia sinensis. Exp Appl Acarol. 2012 Nov;58(3):247-58. doi: 10.1007/s10493-012-9577-2. Epub 2012 Jun 6. 52(7):624-8. doi: 10.1093/chromsci/bmt090. Epub 2013 Jul 3. 28(1):419. doi: 10.3390/molecules28010419.
    4: Shimono M, Koga H, Akagi A, Hayashi N, Goto S, Sawada M, Kurihara T, Matsushita A, Sugano S, Jiang CJ, Kaku H, Inoue H, Takatsuji H. Rice WRKY45 plays important roles in fungal and bacterial disease resistance. Mol Plant Pathol. 2012 Jan;13(1):83-94. doi: 10.1111/j.1364-3703.2011.00732.x. Epub 2011 Jul 4.
    5: Kimura N, Fukuchi A. MBI-D resistance management of Pyricularia oryzae using an application program incorporating benomyl. J Pestic Sci. 2018 Feb 28;43(1):33-35. doi: 10.1584/jpestics.D17-064.

    合成参考文献


    参考文献:10.1021/jf902863z
    摘要:Zuo X, Mi N, Fan Z, Zheng Q, Zhang H, Wang H, Yang Z. Synthesis of 4-methyl-1,2,3-thiadiazole derivatives via Ugi reaction and their biological activities. J Agric Food Chem. 2010 Mar 10;58(5):2755–62. doi: 10.1021/jf902863z.
    参考文献:10.1021/jf9029628
    摘要:Fan Z, Yang Z, Zhang H, Mi N, Wang H, Cai F, Zuo X, Zheng Q, Song H. Synthesis, crystal structure, and biological activity of 4-methyl-1,2,3-thiadiazole-containing 1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles. J Agric Food Chem. 2010 Mar 10;58(5):2630–6. doi: 10.1021/jf9029628.
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