CAS: 214360-60-8; N-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)Phenyl)Acetamide

上下游产品

m-4-acetamidophenyl trifluoromethanesulfonate 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane acetic anhydride 4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)aniline N-(4-allylphenyl)acetamide N-(4-(pyridin-4-yl)phenyl)acetamide 4'-nitrobiphenyl-4-acetanilide (R)-N-{4-[6-(1-aza-bicyclo[2.2.2]°Ct-3-yloxy)-pyridazin-3-yl]-phenyl}-acetamide

📜4'-溴乙酰苯胺置于(1,1'-Bis(Diphenylphosphino)Ferrocene)Palladium(II) Dichloride,Potassium Acetate体系中,用 乙醇 用作溶剂,化学反应 2.5H,反应生成4-乙酰基氨基苯硼酸频哪醇酯
参考文献:Syntheses Of (4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)Arenes Through Pd-Catalyzed Borylation Of Arylbromides With The Successive Use Of 2,2'-Bis(1,3,2-Benzodioxaborole) And Pinacol
标题:Syntheses Of (4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)Arenes Through Pd-Catalyzed Borylation Of Arylbromides With The Successive Use Of 2,2'-Bis(1,3,2-Benzodioxaborole) And Pinacol
摘要:Syntheses Of (4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)Arenes Through The Pd-Catalyzed Borylation Of Arylbromides With The Successive Use Of 2,2'-Bis(1,3,2-Benzodioxaborole) And Pinacol Were Investigated. Pdcl2(Dppf) And Acok In Etoh Or Dmso Successfully Provided (4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)Arenes. In Particular,This Method Was More Effective In The Borylation Of Arylbromides Bearing Sulfonyl Groups Than The Conventional Pd-Catalyzed Borylation Using Pinacolborane Or Bis(Pinacolato)Diboron. (C) 2012 Elsevier Ltd. All Rights Reserved.
Doi:10.1016/j.Tetlet.2012.10.118

专利信息

专利号:US-7122694-B2
优先权日:1998-11-06
标 题 :Hydroboronation process
发明人：MARCUCCIO SEBASTIAN MARIO; RODOPOULOS MARY; WEIGOLD HELMUT
权利人:BORON MOLECULAR PTY LTD
摘要:The invention relates to processes for the synthesis of aryl or alkene borates which comprises reacting: (i) an olefinic compound having a halogen or halogen-like substituent in a vinylic substitution position, or (ii) an aromatic ring having a halogen or halogen-like substituent in a ring substitution position, with a disubstituted monohydroborane in the presence of a Group 8-11 metal catalyst. The invention also relates to the use of these borates in coupling reactions. The invention further relates to certain disubstituted monohydroboranes and aryl or alkene borates.

专利号:US-2025026766-A1
优先权日:2022-01-12
标题 :Thiazolopyridyl Amide Derivatives as DNA Polymerase Theta Inhibitors
发明人：LI JING; XU WENQING; WANG ZHIWEI
权利人:BEIGENE LTD
摘要:The present invention relates to compounds containing thiazolopyridyl amide structure, the process for their synthesis, as well as the use of such compounds for inhibiting DNA Polymerase Theta (Pol Theta), and in the treatment of various diseases including cancers.

专利号:US-8178559-B2
优先权日:2004-12-30
标 题:Organic compounds
发明人：BREITENSTEIN WERNER; EHARA TAKERU; EHRHARDT CLAUS; GROSCHE PHILIPP; HITOMI YUKO; IWAKI YUKI; KANAZAWA TAKANORI; KONISHI KAZUHIDE; MAIBAUM JUERGEN KLAUS; MASUYA KEIICHI; IWASAKI ATSUKO; OSTERMANN NILS; SUZUKI MASAKI; TOYAO ATSUSHI; YOKOKAWA FUMIAKI
权利人:BREITENSTEIN WERNER; EHARA TAKERU; EHRHARDT CLAUS; GROSCHE PHILIPP; HITOMI YUKO; IWAKI YUKI; KANAZAWA TAKANORI; KONISHI KAZUHIDE; MAIBAUM JUERGEN KLAUS; MASUYA KEIICHI; IWASAKI ATSUKO; OSTERMANN NILS; SUZUKI MASAKI; TOYAO ATSUSHI; YOKOKAWA FUMIAKI; NOVARTIS AG
摘要:3,4-substituted piperidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (=disorder) that depends on activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; pharmaceutical formulations comprising a 3,4-substituted piperidine compound, and/or a method of treatment comprising administering a 3,4substituted piperidine compound, a method for the manufacture of a 3,4-substituted piperidine compound, and novel intermediates and partial steps for their synthesis are disclosed. The 3,4-disubstituted piperidine compounds have the formula (I), wherein the symbols have the meanings defined in the specification.