CAS: 205528-32-1; Fmoc-L-(4-Thiazolyl)-Alanine
- 英文名称Fmoc-L-(4-Thiazolyl)-Alanine
- 中文名称Fmoc-3-(4-噻唑基)-L-丙氨酸
- IUPAC名称(S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(thiazol-4-yl)propanoic acid
- 其它别名4-Thiazolepropanoicacid, a-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-,(S)-
- CAS编号205528-32-1
- MFCD编号:MFCD00672568
- EINECS号:800-686-9
- 分子式:C21H18N2O4S分子量:394.44
- 产品CID: 1041578
- 产品分类有机原料→生命科学→氨基酸及其衍生物→丙氨酸及其衍生物
相似化合物
205528-33-2 119434-75-2 119433-80-6物理性质
MSDS等安全信息
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专利信息
专利号:US-8338565-B2
优先权日:2008-08-20
标 题 :Macrocyclic compounds for inhibition of tumor necrosis factor alpha
发明人：LEE JINBO; BOND JULIAN F; TERRETT NICHOLAS; FAVALORO JR FRANK G; WANG DANIEL; BRIGGS TIMOTHY F; SEIGAL BENJAMIN ADAM; SUN WEI-CHUAN; HALE STEPHEN P
权利人:LEE JINBO; BOND JULIAN F; TERRETT NICHOLAS; FAVALORO JR FRANK G; WANG DANIEL; BRIGGS TIMOTHY F; SEIGAL BENJAMIN ADAM; SUN WEI-CHUAN; HALE STEPHEN P; ENSEMBLE THERAPEUTICS CORP
摘要:Disclosed herein are macrocyclic compounds and methods for their synthesis and use. In particular, macrocyclic compounds are disclosed that modulate the activity of tumor necrosis factor alpha and/or are useful in the treatment of medical conditions, such as, rheumatoid arthritis, psoriasis, and asthma.
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主要参考文献
[参考文献]: Luckose F, Et Al. Effects Of Amino Acid Derivatives On Physical, Mental, And Physiological Activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1040.合成参考文献
参考文献:10.1007/s11814-021-0788-2
摘要:Baritugo K, Son J, Sohn YJ, Kim HT, Joo JC, Choi J, Park SJ. Recent progress in metabolic engineering of Corynebacterium glutamicum for the production of C4, C5, and C6 chemicals. Korean Journal of Chemical Engineering. 2021 Jun 11;38(7):1291–307. doi: 10.1007/s11814-021-0788-2.
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