CAS: 5299-60-5; Ethyl 6-Hydroxyhexanoate

相似化合物

73839-20-0 141-28-6 626-86-8

上下游产品

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环己酮置于dipotassium Peroxodisulfate,硫酸体系中,用 乙醇 作为反应溶剂,化学反应 15.0H,以80%的收率获得产物6-羟基己酸乙酯
参考文献:Neocosmosin A的第一个立体选择性全合成:一种简便的方法
标题:Neocosmosin A的第一个立体选择性全合成:一种简便的方法
摘要:据报道,使用容易获得的起始原料,如乙酰乙酸甲酯,环己酮和均烯丙基醇,参与了关键的转化过程,首次合成了具有新的对人阿片和大麻素受体具有亲和力的新霉素a的立体选择性化合物.靶分子的合成涉及三个片段,分别带有酸官能团,(R)-戊-4-烯-2-醇和weinreb酰胺,分别通过四个,八个和三个步骤合成.然后,将片段分四个步骤偶联,以总产率28.6%产生目标分子.
DOI:10.1016/j.Tetlet.2014.08.065

专利信息

专利号:US-6316595-B1
优先权日:1994-03-14
标题 :PNA synthesis using a base-labile amino protecting group
发明人：BREIPOHL GERHARD; UHLMANN EUGEN; KNOLLE JOCHEN
权利人:AVENTIS PHARMA GMBH
摘要:The invention provides compounds and processes for synthesis of peptide nucleic acids (PNA). The compounds include temporary amino protecting groups that are base-labile, and protection groups for the exocyclic amino function of the nucleotide base that is compatible with the base-labile amino protecting group. Cleavage of an oligomer comprising these compounds from a solid support can be achieved using weak or medium strength acids.

专利号:WO-0005208-A9
优先权日:1998-07-24
标 题 :Amino-aldehyde solid support, linker therefor and methods of preparation and use thereof
发明人：SIEV DANIEL V; SEMPLE J EDWARD; ROBERTS CHRISTOPHER A
权利人:CORVAS INT INC
摘要:This invention provides a novel method for solid-phase peptide synthesis wherein a cyclic or linear amino aldehyde is derivatized through linkage to a solid-support, and employed in the production of biologically significant peptides, peptide derivatives, peptidomimetic compounds and analogs thereof. The method of linkage and peptide synthesis, including for combinatorial chemistry, is disclosed.

专利号:EP-1430082-A4
优先权日:2001-09-07
标 题 :SYNTHESIS OF POLYPEPTIDE-OLIGOMERIC CONJUGATES OF INSULIN, AND POLYPEPTIDE-OLIGOMERIC CONJUGATES OF PROINSULIN, AND METHODS OF THEIR SYNTHESIS

专利号:US-2025002644-A1
优先权日:2021-11-11
标题 :Sigmatropic rearrangements of polymer backbones
发明人：ZHUKHOVITSKIY ALEKSANDR V; DITZLER RACHAEL A J
权利人:UNIV NORTH CAROLINA CHAPEL HILL
摘要:The present disclosure relates to polymers, methods for polymer synthesis, and methods of modifying the backbone of said polymers. Modification of the polymer backbone via a sigmatropic rearrangement allows facile entry into new, highly ordered polymers.

专利号:US-2014256904-A1
优先权日:2011-08-15
标 题:Biotechnological synthesis process of omega-functionalized carbon acids and carbon acid esters from simple carbon sources
发明人：SCHAFFER STEFFEN; DECKER NICOLE; GIELEN JASMIN; HAEGER HARALD; HAAS THOMAS; POETTER MARKUS; HENNEMANN HANS-GEORG; WESSEL MIRJA; VOLLAND MICHAEL
权利人:SCHAFFER STEFFEN; DECKER NICOLE; GIELEN JASMIN; HAEGER HARALD; HAAS THOMAS; POETTER MARKUS; HENNEMANN HANS-GEORG; WESSEL MIRJA; VOLLAND MICHAEL; EVONIK DEGUSSA GMBH
摘要:The subject of the invention is a biotechnological process for the production of ω-functionalized carboxylic acids and of ω-functionalized carboxylate esters from simple carbon sources.

专利号:US-4238473-A
优先权日:1975-07-08
标题:Artificial oligosaccharide antigenic determinants
发明人：BAKER DONALD A; BUNDLE DAVID R; LEMIEUX RAYMOND U
权利人:CHEMBIOMED LTD
摘要:Carbohydrate antigenic determinants containing a glycosidically linked bridging arm are synthesized and coupled to carrier molecules to form artificial antigens, and to solid supports to form immunoadsorbents. Various artificial antigens of the blood group type are prepared and applications shown. Specific examples are given to the synthesis of the Lewis-a, Lewis-b, A, B, and H(O) blood group antigens; to the preparation of antisera to these artificial antigens, to the preparation of immunoadsorbents specific for antibodies to these antigens, and to the detection of such antigens wherever they occur.