CAS: 49759-61-7; H-D-Phe(4-Me)-Oh

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1991-87-3 199006-54-7 80102-26-7

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(S)-2-Benzyloxycarbonylamino-3-p-tolyl-propionic acid N-acetyl-4-methyl-phenylalanineN-acetyl-4-methyl-phenylalanine (S)-2-Acetylamino-3-p-tolyl-propionic acid 3-(4-methylphenyl)-2-oxopropanoic acid (S)-2-(2-Nitro-phenylsulfanylamino)-3-p-tolyl-propionic acid (S)-2-Acetylamino-3-p-tolyl-propionic acid 3-(4-hydroxy-3-methylphenyl)-L-alanine L-(p-hydroxymethyl)phenylalanine

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    专利号:US-11453699-B2
    优先权日:2017-04-19
    标 题:Antimicrobial compounds and/or modulators of microbial infections and methods of using the same
    发明人:SCOTT WILLIAM LEONARD; O'DONNELL MARTIN JAMES; SAMARITONI JACK GENO
    权利人:UNIV INDIANA RES & TECH CORP
    摘要:Some embodiments include compounds that can inhibit the growth of bacterial and/or inhibit or reduce microbial infections caused by one or more microorganisms (e.g., Pseudomonas aeruginosa and Cryptococcus neoformans) and methods of using these compounds to treat microbial infection and outbreaks and/or to reduce the formation of biofilms. Other embodiments include synthesis of the compounds that can inhibit the growth of one or more microorganisms and/or inhibit or reduce microbial infections.

    专利号:US-9574189-B2
    优先权日:2005-12-01
    标题:Enzymatic encoding methods for efficient synthesis of large libraries
    发明人:FRANCH THOMAS; LUNDORF MIKKEL DYBRO; JACOBSEN SØREN NYBOE; OLSEN EVA KAMPMANN; ANDERSEN ANNE LEE; HOLTMANN ANETTE; HANSEN ANDERS HOLM; SØRENSEN ANDERS MALLING; GOLDBECH ANNE; DE LEON DAEN; KALDOR DITTE KIEVSMOSE; SLØK FRANK ABILDGAARD; HUSEMOEN GITTE NYSTRUP; DOLBERG JOHANNES; Jensen Kim Birkebæ; PEDERSEN LENE; NØRREGAARD-MADSEN MADS; GODSKESEN MICHAEL ANDERS; GLAD SANNE SCHRØDER; NEVE SØREN; THISTED THOMAS; KRONBORG TINE TITILOLA AKINLEMINU; SAMS CHRISTIAN KLARNER; FELDING JAKOB; FRESKGÃ…RD PER-OLA; GOULIAEV ALEX HAAHR; PEDERSEN HENRIK
    权利人:FRANCH THOMAS; LUNDORF MIKKEL DYBRO; JACOBSEN SØREN NYBOE; OLSEN EVA KAMPMANN; ANDERSEN ANNE LEE; HOLTMANN ANETTE; HANSEN ANDERS HOLM; SØRENSEN ANDERS MALLING; GOLDBECH ANNE; DE LEON DAEN; KALDOR DITTE KIEVSMOSE; SLØK FRANK ABILDGAARD; HUSEMOEN GITTE NYSTRUP; DOLBERG JOHANNES; Jensen Kim Birkebæ; PEDERSEN LENE; NØRREGAARD-MADSEN MADS; GODSKESEN MICHAEL ANDERS; GLAD SANNE SCHRØDER; NEVE SØREN; THISTED THOMAS; KRONBORG TINE TITILOLA AKINLEMINU; SAMS CHRISTIAN KLARNER; FELDING JAKOB; FRESKGÃ…RD PER-OLA; GOULIAEV ALEX HAAHR; PEDERSEN HENRIK; NUEVOLUTION AS
    摘要:Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).

    专利号:US-11702652-B2
    优先权日:2005-12-01
    标题:Enzymatic encoding methods for efficient synthesis of large libraries

    专利号:US-2009264300-A1
    优先权日:2005-12-01
    标题 :Enzymatic encoding methods for efficient synthesis of large libraries

    专利号:US-2020216836-A1
    优先权日:2005-12-01
    标题 :Enzymatic encoding methods for efficient synthesis of large libraries

    专利号:EP-0412508-B1
    优先权日:1989-08-07
    标 题:Analogues of vasopressin, their preparation and pharmaceutical use
    发明人:PROCHAZKA ZDENKO; BLAHA IVO; ZERTOVA MIROSLAVA; SLANINOVA JIRINA; VELEK JIRI; SKOPKOVA JANA; LEBL MICHAL; BARTH TOMISLAV; MALETINSKA LENKA; VILHARDT HANS
    权利人:CESKOSLOVENSKA AKADEMIE VED
    摘要:The invention relates to analogues of 8-D-homoarginine-vasopressin of the general formula in which the meanings are: X L-O-methyltyrosine L-p-ethylphenylalanine D-p-ethylphenylalanine L-p-methylphenylalanine or D-p-methylphenylalanine and R cysteine or beta -mercaptopropionic acid to a process for the preparation thereof by solid-phase synthesis and to the pharmaceutical use thereof. The analogues of vasopressin have a selectively increased affinity for uterine oxytocin receptors, where they have an antagonistic action to oxytocin. The analogues of deaminovasopressin furthermore have a significantly reduced antidiuretic activity compared with [8-D-arginine]-deaminovasopressin.
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    主要参考文献

    [参考文献]: Luckose F, Et Al. Effects Of Amino Acid Derivatives On Physical, Mental, And Physiological Activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-809.

    合成参考文献


    摘要:Parmeggiani, F.; Galman, J. L.; Montgomery, S. L.; Turner, N. J., Science of Synthesis, (2019) , 408.
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