CAS: 4467-07-6; 3-(Pyridin-2-yl)Benzoic Acid

相似化合物

85553-53-3 4385-62-0 98061-20-2

上下游产品

CAS号109-04-6 2-溴吡啶 | CAS号25487-66-5 3-羧基苯硼酸 | CAS号591-17-3 3-溴甲苯 | CAS号4373-61-9 2-(间甲苯基)吡啶

📜2-(3-甲苯基)吡啶置于potassium Permanganate体系中,用 叔丁醇 作为反应溶剂,化学反应生成 3-(2-吡啶)苯甲酸
参考文献:Ncn钯钳通过透汞.[2-(2-恶唑啉)-6-(2-吡啶基)]苯基氯化钯(II)的合成及其在suzuki偶联中的催化活性
标题:Ncn钯钳通过透汞.[2-(2-恶唑啉)-6-(2-吡啶基)]苯基氯化钯(II)的合成及其在suzuki偶联中的催化活性
摘要:摘要 以间溴甲苯为原料,经过一系列转化,合成了不对称ncn配体1-(2-恶唑啉基)-3-(2-吡啶基)苯6.6 与乙酸汞 (II) 反应反应生成汞衍生物 7,通过转汞作用将其转化为相应的 Ncn 钯钳 8.还研究了乙腈中 6-8 的紫外光谱.通过x射线单晶衍射进一步证实了6和8的结构.研究了由8催化的芳基卤化物与苯基硼酸之间的碳-碳交叉偶联反应.结果表明,与芳基氯化物相比,这种钯钳对芳基溴化物的偶联具有更高的活性.
DOI:10.1016/j.Inoche.2013.03.012

专利信息

专利号:US-8017786-B2
优先权日:2006-05-15
标 题:Substituted β-phenyl-α-hydroxy-propanoic acid, synthesis method and use thereof
发明人：ZHENG XIAOHUI; ZHANG QUNZHENG; WANG SHIXIANG; ZHAO XINFENG
权利人:UNIV NORTHWEST
摘要:The present invention relates to a compound of the formula (I), wherein R 1 , R 2 and R 3 are each independently selected from H, OH, F, Cl, Br, methoxy and ethoxy; or alternatively, R 1 and R 2 together form —OCH 2 O—, R 3 is selected from H, OH, methoxy, ethoxy and halogens; R 4 is OH or acyloxy; R 5 is cycloalkoxyl, amino and substituted amino, and when R 5 is selected from amino, at least one of R 1 , R 2 and R 3 is not H. The present invention further relates to a process for synthesizing a compound of the formula (I), and use of the compound of the formula (I) in the manufacture of a medicament for the prevention or treatment of cardiovascular or cerebrovascular diseases.