N,N-二甲基正辛胺置于tris(Triphenylphosphine)Ruthenium(II) Chloride体系中,用 四氢呋喃 作为反应溶剂,化学反应 7.0H,以85%的收率获得产物二辛基甲胺 参考文献:The Homogeneously Catalysed Synthesis Of N-Methyldi-Alkylamines From N-Methyl And N,N-Dimethylalkylamines 标题:The Homogeneously Catalysed Synthesis Of N-Methyldi-Alkylamines From N-Methyl And N,N-Dimethylalkylamines 摘要: DOI:10.1016/s0022-328X(00)81961-0
专利号:US-9006347-B2 优先权日:2011-09-08 标 题 :Method of synthesising polycarbonates in the presence of a bimetallic catalyst and a chain transfer agent 发明人:WILLIAMS CHARLOTTE K; KEMBER MICHAEL; BUCHARD ANTOINE; JUTZ FABIAN 权利人:IMP INNOVATIONS LTD 摘要:The invention provides a process for the synthesis of a polycarbonate, the process comprising the step of reacting carbon dioxide with at least one epoxide in the presence of a catalyst of formula (I) and a chain transfer agent. The invention also provides a polymerization system for the copolymerization of carbon dioxide and at least one epoxide comprising a catalyst of formula (I) and a chain transfer agent, polycarbonates produced by the inventive process, a block copolymer comprising a polycarbonate produced by the inventive process, and a method of producing the block copolymer. The invention also relates to novel catalysts of formula (III).
专利号:US-4912269-A 优先权日:1987-07-10 标题 :Synthesis of perfluoroalkyl bromides 发明人:DRIVON GILLES; DURUAL PIERRE; GURTNER BERNARD; LANTZ ANDRE 权利人:ATOCHEM 摘要:The invention relates to the preparation of perfluoroalkyl bromides or bromoperfluoroalkanes, CnF 2n+1 -Br (n=1 to 20). n Gaseous hydrogen bromide is reacted with a perfluoroalkanesulphonyl chloride, C n F 2n+1 -SO 2 Cl, in the presence of a catalyst consisting of a tertiary amine or phosphine or a quaternary ammonium or phosphonium salt, at a temperature ranging from 80° to 200° C.
专利号:US-5840879-A 优先权日:1996-12-06 标题 :Reagents and solid supports for improved synthesis and labeling of polynucleotides 发明人:WANG EDGE R 摘要:The invention provided methods and compositions for oligonucleotide synthesis and labeling. The subject compounds have either rigid ring or long linear linker structures and provide enhanced coupling efficiencies over prior art labeling reagents because of lack of stereo hindering and/or provide more convenient and cost-effective syntheses. These novel linkers also contain a base labile structure which provides: labeling at 3' end with regular solid supports, cleaving under mild conditions, and achieving higher yield because of the complete cleavage and higher purity because the mild conditions will not bring down the impurities on the solid support. When used in a solid support pre-attached with either a nucleotide for unlabeled oligonucleotide synthesis, or a label for 3' end labeled oligonucleotide synthesis, or an alternate structure to use as an universal support, these linkers provide solid supports requiring only mild cleavage conditions.
专利号:US-6409988-B1 优先权日:1999-07-01 标 题:Radiolabeled 1-aryl pyrazoles, the synthesis thereof and the use thereof as pest GABA receptor ligands 发明人:DHANOA DALJIT S; MEEGALLA SANATH; DOLLER DARIO; SOLL RICHARD M 权利人:DIMENSIONAL PHARM INC 摘要:The present invention is directed to radiolabeled compounds of Formula I:or salts thereof, whereR1 represents R8, R8O, R8SO2, R8SO or R8S in which R8 is tritiated or deuterated methyl;X is halo, cyano, C1-6 alkoxycarbonyl, C2-6 alkynyl, optionally substitutedC6-14 aryl or an optionally substituted 5- to 7-membered heteroaromatic ring linked to thiazole via a carbon-carbon bond;R2 is hydrogen or amino; andR3-R7 are defined in the specification.The invention is also directed to methods of using such compounds for demonstrating specific insect GABA receptors, qualitatively screening for compounds acting on an insect GABA receptor or quantitatively assaying concentrations of a compound acting on an insect GABA receptor.
专利号:US-2024336916-A1 优先权日:2020-03-26 标 题:Synthesis of modified oligonucleotides with increased stability
专利号:US-2007161778-A1 优先权日:2005-12-29 标题:Use of Acid Scavengers for the Synthesis of Standard Lenght and Long-Mer Nucleic Acid Arrays
[参考文献]: J J Harding, Et Al. Free And Protein-Bound Glutathione In Normal And Cataractous Human Lenses. Biochem J. 1970 May;117(5):957-60. [参考文献]: Vanessa G Correia, Et Al. Oxazoline-Based Antimicrobial Oligomers: Synthesis By Crop Using Supercritical Co2. Macromol Biosci. 2011 Aug 11;11(8):1128-37.
合成参考文献
参考文献:10.1021/ac103311p 摘要:Seliman AF, Samadi A, Husson SM, Borai EH, DeVol TA. Preparation of polymer-coated, scintillating ion-exchange resins for monitoring of 99Tc in groundwater. Anal Chem. 2011 Jun 15;83(12):4759–66. doi: 10.1021/ac103311p.