CAS: 22961-45-1; N-Phenylpyridin-4-Amine

该化合物是一种有机化合物,其特征是存在一个苯基组和一个丙烯胺协会,该化合物的特征是四级和氮原子的一个氨基组和一个苯基组,以氨基环替代一个4级和氮原子的一个丙烯基环,通常是一种固态或晶状物质,在有机溶剂中可溶解;氨基氨基组的存在有助于其基本性和潜在再活动,使它成为各种化学反应的候选体,包括涉及电子药用芳香替代的化学反应.N-Phenyl-4-pyridinamina可能展示生物活动,这可能对药物研究感兴趣,特别是针对特定生物途径的药物开发具有兴趣,其结构特征允许与生物分子的潜在互动,使其成为医学化学研究的主题.在处理和使用时,应参考安全数据,如同任何化学物质一样,以确保采取适当的预防措施.

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欧盟法规

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上下游产品

4-Chloropyridine aniline 4-chloropyridine N-oxide 4-phenoxypyridine N-Phenyl-N-(4-pyridinyl)benzamide 1-(4-pyridyl)-3-n-butyl-4-hydroxy-2(1H)-quinolone 1-phenyl-3-n-butyl-1,6-naphthyridin-2(1H)-one benzothiazine10H-pyrido3,4-b1,4benzothiazine

合成工艺路线路线简述

    📜4-苯基硫基吡啶置于aniline Hydrochloride体系中,化学反应生成4-苯氨基吡啶
    参考文献:Jerchel; Jakob,Chemische Berichte,1958,Vol. 91,P. 1266,1272
    标题:Jerchel; Jakob,Chemische Berichte,1958,Vol. 91,P. 1266,1272

    海关参考信息

    专利信息


    专利号:US-4031106-A
    优先权日:1973-12-19
    标题:Synthesis of aromatic amines by reaction of aromatic compounds with ammonia
    发明人:DELPESCO THOMAS WAYNE
    权利人:DU PONT
    摘要:An improved process is provided for producing an aromatic amine from ammonia and an aromatic compound which comprises reacting the aromatic compound with ammonia at a temperature of from about 150 DEG C. to about 500 DEG C. and at a pressure of from about 10 to about 1000 atmospheres in the presence of a conditioned nickel/nickel oxide/zirconium oxide cataloreactant containing an oxide of lanthanum, samarium, holmium, europium, erbium, yttrium, praseodymium, neodymium, terbium, ytterbium, dysprosium or a mixture of any of them.

    专利号:US-3821231-A
    优先权日:1971-10-15
    标 题 :Method for preparation of n-substituted 4-aniline piperidines
    发明人:LAVRINOVICH E; GERMANE S; TREIGUTE I; EDZHIN M
    权利人:LAVRINOVICH E; GERMANE S; TREIGUTE I; EDZHIN M
    摘要:A method for the preparation of N-substituted 4-anilino piperidines having the general formula WHERE R is an alkyl group having from 1 to 16 carbon atoms, C6H5CH2-, or C6H5(CH2)2-, comprising reacting 4-anilinopyridine with an alkyl or aralkyl halide having the general formula R-X, where R is an alkyl group having from 1 to 16 carbon atoms, C6H5CH2-, or C6H5(CH2)2- and X is Cl, Br or I, with subsequent reduction of the formed N-substituted 4-anilinopyridinium quarternary salt with sodium borohydride in an aqueous-organic solvent and isolation of the main product. The proposed invention can be used in the synthesis of certain medical preparations, for example analgesic phentanyl and some other physiologically active compounds.

    专利号:US-3929889-A
    优先权日:1971-02-16
    标 题 :Synthesis of aromatic amines by reaction of aromatic compounds with ammonia
    发明人:SQUIRE EDWARD NOONAN
    权利人:DU PONT
    摘要:An improved process for producing an aromatic amine is provided in which an aromatic compound is reacted with ammonia in the presence of a conditioned nickel/nickel oxide cataloreactant at a temperature of from about 150*C. to about 500*C. and at a pressure of from about 10 to about 1000 atmospheres.

    专利号:US-4001260-A
    优先权日:1973-12-19
    标 题:Synthesis of aromatic amines by reaction of aromatic compounds with ammonia
    发明人:DEL PESCO THOMAS W
    权利人:DU PONT
    摘要:An improved process is provided for producing an aromatic amine from ammonia and an aromatic compound which comprises reacting the aromatic compound with ammonia at a temperature of from about 150° C. to about 500° C. and at a pressure of from about 10 to about 1000 atmospheres in the presence of a conditioned nickel/nickel oxide/zirconium oxide cataloreactant which has been treated with ammonia prior to introduction of the cataloreactant to the amination reactants.

    专利号:US-7741487-B2
    优先权日:2004-08-26
    标题 :Method for producing quaterrylene-3,4:13, 14-tetracarboxy diimides by direct synthesis
    发明人:KOENEMANN MARTIN; BOEHM ARNO; BIDLINGMAIER HERMANN; RIEGER REINHOLD; BLASCHKA PETER; REICHELT HELMUT; KRIEGER MATTHIAS
    权利人:BASF AG
    摘要:A process for preparing quaterrylene-3,4:13,14-tetracarboximides of the general formula I n nin whichn nR, R′ are each independently hydrogen or optionally substituted C 1 -C 30 -alkyl, C 5 -C 8 -cycloalkyl or aryl or hetaryl;n nwhich comprises reacting a perylene-3,4-dicarboximide of the general formula IIan n nin the presence of a base-stable, high-boiling, organic solvent and of an alkali metal base or alkaline earth metal base, with a perylene-3,4-dicarboximide of the general formula IIbn n nin which X is hydrogen, bromine or chlorine.

    专利号:US-7358362-B2
    优先权日:2004-01-23
    标题:Method for the production of terylene-3,4:11,12-tetracarboxydiimides by direct synthesis
    发明人:KOENEMANN MARTIN; BOEHM ARNO; HELFER WILLI; ROMEIS JUERGEN; QU JIANQIANG; MUELLEN KLAUS
    权利人:BASF AG; MAX PLANCK GESELLSCHAFT
    摘要:A process for preparing terylene-3,4:11,12-tetracarboximides I n nwhere the variables are each defined as follows:n R, R′ are each independently hydrogen; if desired substituted alkyl or cycloalkyl; R 1 is hydrogen or alkyl; R 2 is hydrogen; alkyl; if desired substituted aryl or hetaryl,n nby reacting a perylene-3,4-dicarboximide IIn n nin the presence of a base-stable, high-boiling organic solvent and of an alkali metal or alkaline earth metal base, with a naphthalene-1,8-dicarboximide IIIn n nin which X is hydrogen, bromine or chlorine.

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    合成参考文献


    摘要:Joule, J. A., Science of Synthesis Knowledge Updates, (2018) 2, 261.
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