CAS: 20082-71-7; Chlorodimethyl(Pentafluorophenyl)Silane

上下游产品

(pentafluorophenyl)dimethylsilane Dimethyl-(pentafluorphenyl)-ethoxysilan 2,3,4,5,6-pentafluorophenylmagnesium bromide dimethyl-2,2,3,3-tetrafluoropropoxychlorosilaneflophenesylsilyl cianide 9,10-bis{2-[(pentafluorophenyl)dimethylsilyl]phenyl}anthracene ((3,5-dimethoxyphenyl)ethynyl)dimethyl(perfluorophenyl)silane fluorodimethylsilylpentafluorobenzene

(Pentafluorophenyl)Dimethylsilane置于氯体系中,用 四氯化碳 用作溶剂,化学反应生成氯二甲基(五氟苯基)硅烷
参考文献:Klebanskii,A.L. Et Al.,Journal Of General Chemistry Of The Ussr,1969,Vol. 39,P. 2248-2250
标题:Klebanskii,A.L. Et Al.,Journal Of General Chemistry Of The Ussr,1969,Vol. 39,P. 2248-2250

专利信息

专利号:US-9605019-B2
优先权日:2011-07-19
标 题:Methods for the synthesis of functionalized nucleic acids
发明人：VERDINE GREGORY L; MEENA; IWAMOTO NAOKI; BUTLER DAVID CHARLES DONNELL
权利人:VERDINE GREGORY L; MEENA; IWAMOTO NAOKI; BUTLER DAVID CHARLES DONNELL; WAVE LIFE SCIENCES LTD
摘要:The present application, among other things, provides technologies, e.g., reagents, methods, etc. for preparing oligonucleotides comprising phosphorothiotriesters linkages, e.g., oligonucleotides having the structure of IIIa, IIIb or IIIc. In some embodiments, provided methods comprise reacting an H-phosphonate of structure Ia or Ib with a silylating reagent to provide a silyloxyphosphonate, and reacting the silyloxyphosphonate with a thiosulfonate reagent of structure IIa or IIb to provide an oligonucleotide of structure IIIa or IIIb. In some embodiments, provided methods comprise reacting an H-phosphonate of structure Ic with a silylating reagent to provide a silyloxyphosphonate, reacting the silyloxyphosphonate with a bis(thiosulfonate) reagent of structure IVc to provide a phosphorothiotriester comprising a thiosulfonate group of structure Vc, and then reacting the phosphorothiotriester comprising a thiosulfonate group of structure Vc with a nucleophile of structure VIc to provide an oligonucleotide of structure IIIc.

专利号:US-2018222936-A1
优先权日:2011-07-19
标 题:Methods for the synthesis of functionalized nucleic acids

专利号:CA-2842358-A1
优先权日:2011-07-19
标题 :Methods for the synthesis of functionalized nucleic acids

专利号:JP-6128529-B2
优先权日:2011-07-19
标题:Methods for the synthesis of functionalized nucleic acids

专利号:CA-2842358-C
优先权日:2011-07-19
标题 :Methods for the synthesis of functionalized nucleic acids

专利号:US-10280192-B2
优先权日:2011-07-19
标题:Methods for the synthesis of functionalized nucleic acids