CAS: 16233-51-5; 1H-Thieno[3,2-D]Pyrimidine-2,4-Dione

相似化合物

35265-80-6 1442082-86-1 41102-03-8

上下游产品

CAS号22288-78-4 3-氨基-2-噻吩甲酸甲酯 | CAS号57-13-6 尿素 | CAS号917-61-3 氰酸钠 | CAS号51322-68-0 methyl 3-[(amin... | CAS号147123-47-5 3-氨基噻吩-2-羧酰胺 | CAS号590-28-3 氰酸钾 | CAS号137844-98-5 2-Thiophenecarb... | CAS号147123-50-0 1H-thieno[3,2-d... | CAS号41102-25-4 7-溴-2,4-二氯噻吩并[3... | CAS号885618-31-5 2-氯-4-吗啉代噻吩并[3,... | CAS号957054-30-7 2-(1H-吲唑-4-基)-6... | CAS号1119280-68-0 2-氯噻吩并[3,2-D]嘧啶 | CAS号16234-14-3 2,4-二氯噻吩并[3,2-D]嘧啶 | CAS号16234-15-4 2-氯-4-(4-吗啉基)噻吩... | CAS号1152475-42-7 7-溴-2-氯噻吩并[3,2-d]嘧啶 | CAS号885675-66-1 2-氯-6-(4-甲烷磺酰基-... | CAS号885698-97-5 2-氯-4-(4-吗啉)噻吩并... | CAS号885698-98-6 4-(6-(溴甲基)-2-氯噻...

3-氨基-2-噻吩甲酰肼置于盐酸,Sodium Nitrite体系中,用 水 用作溶剂,化学反应 0.58H,反应生成1,3-二氢噻吩[3,2-D]嘧啶-2,4-二酮
参考文献:Huddleston,Patrick R.; Barker,John M.; Adamczewska,Yolante Z.,Journal Of Chemical Research,Miniprint,1993,# 2,P. 548-575
标题:Huddleston,Patrick R.; Barker,John M.; Adamczewska,Yolante Z.,Journal Of Chemical Research,Miniprint,1993,# 2,P. 548-575

专利信息

专利号:US-9895374-B2
优先权日:2015-03-02
标 题:Thieno- and pyrrolopyrimidine analogues as anticancer agents and methods of use thereof
发明人：RADTKE KATHERINE L; TEMBURNIKAR KARTIK
权利人:UNIV MARYLAND
摘要:The present invention provides for the design and synthesis of halogenated thieno- and pyrrolopyrimidine compounds that exhibit cancer proliferation inhibitory activity and the use thereof for cancer treatment.

专利号:US-10646490-B2
优先权日:2015-03-02
标 题 :Thieno- and pyrrolopyrimidine analogues and prodrugs thereof as anticancer agents and methods of use thereof
发明人：RADTKE KATHERINE L
权利人:UNIV MARYLAND
摘要:The present invention provides for the design and synthesis of halogenated thieno- and pyrrolopyrimidine compounds and prodrugs thereof that exhibit cancer proliferation inhibitory activity and the use thereof for cancer treatment.

专利号:US-6084097-A
优先权日:1997-10-20
标题:Methods for preparing 1-[4-arylpiperazin-1-yl]-3-[2-oxopyrrolidin/piperidin-1-yl] propanes
发明人：SINHA NEELIMA; JAIN SANJAY; SAXENA ANIL KUMAR; ANAND NITYA; SAXENA RAM MOHAN; DUBEY MANGAL PRASAD; RAY MADHUR; PATNAIK GYANENDRA KUMAR
权利人:COUNCIL SCIENT IND RES
摘要:The invention relates to a process for the synthesis of 1-[4-Arylpiperazin-1-yl]-3-[2-oxopyrrolidin/piperidin-1-yl]propanes used as potential therapeutic agents for hypertension, ischemia, cardiovascular and other adrenergic receptors related disorders, having general formula 1 ##STR1## wherein Ar represents a phenyl ring substituted by the groups like halo, alkoxy, alkyl or heteroaryl, n=1 or n=2; a process of preparing said compounds and a method of treating hypertension, ischemia, cardiovascular and other adrenergic receptors related disorders.

专利号:US-4670560-A
优先权日:1986-04-28
标 题:Thienopyrimidine-2,4-dione derivatives and intermediates thereof
发明人：PRESS JEFFERY B; RUSSELL RONALD K
权利人:ORTHO PHARMA CORP
摘要:The synthesis of thienopyrimidine-2,4-dione derivatives and their urea intermediates is described. The novel urea intermediates and thienopyrimidine-2,4-dione derivatives are generally vasodilating agents and anti-hypertensive agents. The compounds are useful as cardiovascular agents.

专利号:US-4707550-A
优先权日:1986-04-28
标题 :N-(substituted thienyl)-N'-(substituted piperazinyl)-ureas
发明人：PRESS JEFFERY B; RUSSELL RONALD K
权利人:ORTHO PHARMA CORP
摘要:The synthesis of thienopyrimidine-2,4-dione derivatives and their urea intermediates is described. The novel urea intermediates and thienopyrimidine-2,4-dione derivatives are general vasodilating agents and anti-hypertensive agents. The compounds are useful as cardiovascular agents.

专利号:EP-0913397-B1
优先权日:1997-10-22
标题:A proces for the synthesis of 1-(4-Arylpiperazine-1-y1)-3-(2-oxypyrrolidin/piperidin-1-yl)propanes as therapeutic agents for hypertension, ischemia, cardiovascular and other adrenergic receptors related disorders
发明人：SINHA NEELIMA; JAIN SANJAY; SAXENA ANIL KUMAR; ANAND NITYA; SAXENA RAM MOHAN; DUBEY MANGAL PRASAD; PATNAIK GYANENDRA KUMAR
权利人:COUNCIL SCIENT IND RES