专利号:US-8202985-B2 优先权日:2005-10-31 标 题:Monomer compositions for the synthesis of polynucleotides, methods of synthesis, and methods of deprotection 发明人:DELLINGER DOUGLAS J; TIMAR ZOLTAN; SIERZCHALA AGNIESZKA; DELLINGER GERALDINO; CARUTHERS MARVIN H 权利人:DELLINGER DOUGLAS J; TIMAR ZOLTAN; SIERZCHALA AGNIESZKA; DELLINGER GERALDINO; CARUTHERS MARVIN H; AGILENT TECHNOLOGIES INC; UNIV COLORADO 摘要:Nucleotide monomers, polynucleotides, methods of making each, and methods of deprotecting each, are disclosed. An embodiment of the nucleotide monomer, among others, includes a nucleotide monomer having a heterobase protecting group selected from structures I through III as described herein. An embodiment of the polynucleotide, among others, includes a plurality of nucleotide moieties having a heterobase protecting group selected from one of structures I through III as described herein.
专利号:US-7759471-B2 优先权日:2005-10-31 标题 :Monomer compositions for the synthesis of RNA, methods of synthesis, and methods of deprotection 发明人:DELLINGER DOUGLAS J; TIMAR ZOLTAN; SIERZCHALA AGNIESZKA; DELLINGER GERALDINE; CARUTHERS MARVIN H 权利人:AGILENT TECHNOLOGIES INC; UNIV COLORADO 摘要:Nucleotide monomers, polynucleotides, methods of making each, methods of deprotecting each, and the like are disclosed herein.
专利号:US-9181292-B2 优先权日:2011-01-05 标题 :Methods for preparation of glycosphingolipids and uses thereof 发明人:LIANG PI-HUI 权利人:LIANG PI-HUI 摘要:Methods for synthesis and preparation of alpha-glycosphingolipids are provided. Methods for synthesis of α-galactosyl ceramide, and pharmaceutically active analogs and variants thereof are provided. Novel alpha-glycosphingolipids are provided, wherein the compounds are immunogenic compounds which serve as ligands for NKT (natural killer T) cells.
专利号:US-2013172553-A1 优先权日:2009-11-25 标题 :Chiral synthesis of isoxazolines, isoxazoline compounds, and uses thereof 发明人:SIELECKI-DZURDZ THAIS; PRUITT JAMES 权利人:SIELECKI-DZURDZ THAIS; PRUITT JAMES; CPSI STOCKHOLDER TRUST 摘要:Processes for the chiral syntheses of isoxazolines and intermediates are described. Compounds prepared thereby, and methods of using the compounds are also described.
专利号:US-9023316-B2 优先权日:2010-04-08 标题:Synthesis of 18F-labeled tracers in hydrous organic solvents 发明人:GANGADHARMATH UMESH; WALSH JOSEPH; KOLB HARTMUTH 权利人:GANGADHARMATH UMESH; WALSH JOSEPH; KOLB HARTMUTH; SIEMENS MEDICAL SOLUTIONS 摘要:A method for synthesizing an 18 F-labeled probe. The method includes a step of eluting an amount of 18 F with a first solvent which includes a predetermined amount of water and at least one organic solvent. In this step, the 18 F elutes as an 18 F solution. The method also includes a step of using the 18 F solution to perform 18 F-labeling in the presence of at least one labeling reagent and at least one phase transfer catalyst so as to generate the 18 F-labeled probe. In the method, there is no step of drying the 18 F starting from a time when the eluting step is performed and ending at a time when the 18 F-labeling step is performed.
专利号:US-2007100138-A1 优先权日:2005-10-31 标题:Monomer compositions for the synthesis of polynucleotides, methods of synthesis, and methods of deprotection
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合成参考文献
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