CAS: 1498-54-0; Diethylphosphoramidic Dichloride

该化合物是一种多用途有机磷化合物,其分子式为C4H10Cl2NO2P.它是合成磷衍生物的关键中间体,广泛用于农用化学,制药和阻燃剂.由于存在两个氯原子,该化合物具有高度的再活动性,从而能够产生有效的核生殖替代反应.该化合物的二乙基氨基混合物组增强了稳定性,同时允许进一步实现功能化.二氯化乙基二醇因其在生产杀虫剂和...

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上下游产品

diethyl amine hydr°Chloride diethylamine N-chlorodiethylamine diethylphosphoramidous dichlorideDiethylamido-phosphorsaeure-bis-ethylenimid cyano-phosphonic acid ethyl ester-diethylamide Butyldiaethylamid°Chlorphosphat diphenyl diethylphosphoramidate

合成工艺路线路线简述

    📜N-Chlorodiethylamine置于二氧化硫,三氯化磷体系中,用 四氯化碳 用作溶剂,化学反应生成二乙基二氯膦酰胺
    参考文献:Petrov,K.A. Et Al.,Journal Of General Chemistry Of The Ussr,1961,Vol. 31,P. 1265-1269
    标题:Petrov,K.A. Et Al.,Journal Of General Chemistry Of The Ussr,1961,Vol. 31,P. 1265-1269

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    合成参考文献


    参考文献:10.1007/s00216-004-2873-x
    摘要:Palit M, Pardasani D, Gupta AK, Shakya P, Dubey DK. Microsynthesis and electron ionisation mass spectrometric analysis of chemical weapons convention (CWC)-related O,O-dialkyl-N,N-dialkylphosphoramidates. Analytical and Bioanalytical Chemistry. 2004 Dec 15;381(2):477–86. doi: 10.1007/s00216-004-2873-x.
    参考文献:10.1007/s002800050049
    摘要:Flowers JL, Ludeman SM, Gamcsik MP, Colvin OM, Shao K, Boal JH, Springer JB, Adams DJ. Evidence for a role of chloroethylaziridine in the cytotoxicity of cyclophosphamide. Cancer Chemotherapy and Pharmacology. 2000 Mar 06;45(4):335–44. doi: 10.1007/s002800050049.
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