CAS: 1194-78-1; 6-Chloropyrimidine-2,4,5-Triamine

相似化合物

4316-98-7 130838-36-7 156-83-2

上下游产品

2,5-diamino-4,6-dichloropyrimidine -2,4-pyrimidinediamine6-chloro-5-(4-chlorophenyl)azo-2,4-pyrimidinediamine ethyl 2-cyanoacetate 7-chloro-1H-[1,2,3]triazolo[4,5-d]pyrimidine-5-amine 2-amino-6-chloropurine

📜2,5-二氨基-4,6-二氯嘧啶置于ammonium Hydroxide体系中,化学反应 24.0H,以93%的收率获得2,4,5-三氨基-6-氯嘧啶
参考文献: Compounds For Treating Cystic Fibrosis[fr] Composés Pour Le Traitement De La Fibrose Kystique
标题: Compounds For Treating Cystic Fibrosis[fr] Composés Pour Le Traitement De La Fibrose Kystique

专利信息

专利号:US-10676445-B1
优先权日:2019-06-06
标 题:Synthesis of aminopyrimidine-based energetic materials
发明人：WILHELM CHRISTOPHER; FOROHAR FARHAD; SOTO DENISSE
权利人:US NAVY
摘要:A new azido compound, 5-amino-6-chloro-2,4-diazido-pyrimidine, and a process for synthesizing. The synthesis may include reacting 5-amino-2,4,6-trichloropyrimidine and sodium azide. There is an excess molar amount of sodium azide for each chloro fractional molar amount on the 5-amino-2,4,6-trichloropyrimidine. The synthesis is a two phase reaction that is a dispersion. The 5-amino-2,4,6-trichloropyrimidine dissolved in acetone is a liquid phase, and the sodium azide is insoluble in acetone and is a solid phase, that is present in excess of chemical equivalents. The reaction product is soluble in acetone, and the reaction by-product, sodium chloride is also insoluble in acetone, and the crude yield is about 92%. Unreacted sodium azide and formed sodium chloride are removed by filtration.