CAS: 100981-43-9; (E)-N'-((4-Bromophenyl)Sulfonyl)-N-(2-(((2-Guanidinothiazol-4-yl)Methyl)Thio)Ethyl)Formimidamide

上下游产品

CAS号100981-68-8 ethyl 4-bromobe... | CAS号69014-10-4 2-[(2-guanidino... | CAS号71916-66-0 2-[4-(2-aminoet... | CAS号701-34-8 4-溴苯磺酰胺 | CAS号81152-53-6 2-[4-(氯甲基)-1,3-...

📜4-溴苯磺酰胺置于氢氧化钾体系中,用 甲醇 用作溶剂,化学反应 4.0H,反应生成乙溴替丁
参考文献:Inhibitors Of Gastric Acid Secretion: N-Sulphonyl Formamidines In A Series Of New Histamine H2-Receptor Antagonists
标题:Inhibitors Of Gastric Acid Secretion: N-Sulphonyl Formamidines In A Series Of New Histamine H2-Receptor Antagonists
摘要:
Doi:10.1016/0223-5234(88)90174-2

专利信息

专利号:US-7256205-B2
优先权日:1998-11-17
标题 :Nitrosated and nitrosylated H2 receptor antagonist compounds, compositions and methods of use
发明人：GARVEY DAVID S; LETTS L GORDON; LIN CHIA-EN; WANG TIANSHENG
权利人:NITROMED INC
摘要:The invention describes novel nitrosated and/or nitrosylated H 2 receptor antagonist compounds, and novel compositions comprising at least one H 2 receptor antagonist compound that is optionally substituted with at least one NO and/or NO 2 group, and, optionally, at least one compound that donates, transfers or releases nitric oxide, stimulates endogenous synthesis of nitric oxide, elevates endogenous levels of endothelium-derived relaxing factor or is a substrate for nitric oxide synthase and/or at least one nonsteroidal antiinflammatory drug, antacid, bismuth-containing reagent or anti-viral agent. The invention also describes methods for treating and/or preventing gastrointestinal disorders; improving gastroprotective properties of H 2 receptor antagonists; decreasing the recurrence of ulcers; facilitating ulcer healing; preventing and/or treating inflammations and microbial infections, ophthalmic diseases and disorders, multiple sclerosis, and viral infections; and decreasing or reducing the gastrointestinal toxicity associated with the use of nonsteroidal antiinflammatory compounds.

专利号:US-2014315720-A1
优先权日:2012-10-24
标 题 :Polysaccharide ester microspheres and methods and articles relating thereto
发明人：FALLON DENIS G; GARRETT THOMAS S; KIZER LAWTON E; ZAZZARA KAREN L; COMBS MICHAEL T; JOHNSON RICHARD K; DEHART GARY
权利人:CELANESE ACETATE LLC
摘要:A method for producing a polysaccharide ester microsphere may include forming a polysaccharide ester product from a polysaccharide synthesis, wherein the polysaccharide ester product comprises a polysaccharide ester and a solvent; diluting the polysaccharide ester product, thereby yielding a polysaccharide ester dope; and forming a plurality of polysaccharide ester microspheres from the polysaccharide ester dope. Suitable polysaccharides may include, but are not limited to, starch, cellulose, hemicellulose, algenates, chitosan, and any combination thereof. Esters thereof may be organic esters (e.g., acetate and the like), inorganic esters (e.g., sulfonates and the like), or combinations thereof. Further, the solids conent of the polysaccharide ester dope, in some instances, may be greater than about 16 wt %.