CAS: 776-04-5; 2-(Trifluoromethyl)Benzenesulfonyl Chloride

上下游产品

CAS号111711-80-9 5-ethoxy-1-[2-(... | CAS号1869-24-5 邻三氟甲基苯磺酰胺

Benzyl 2-Trifluoromethylphenyl Sulfide置于1,3-二氯-5,5-二甲基海因,溶剂黄146体系中,用 二氯甲烷,水 作为反应溶剂,以88%的收率获得产物2-三氟甲基苯磺酰氯
参考文献:一种简单且高效的氧化氯化方案,用于制备芳磺酰氯
标题:一种简单且高效的氧化氯化方案,用于制备芳磺酰氯
摘要:发现2,4-二氯-5,5-二甲基乙内酰脲(dcdmh)是一种温和而有效的试剂,可通过氧化氯化以高至极好的收率将硫化合物直接氧化转化为相应的芳烃磺酰氯.该方法适用于多种类型的硫底物(硫醇,二硫化物和苄基硫化物).整个过程简单,实用,并且可以方便地获得各种芳基或杂芳基磺酰氯.温和的反应条件和广泛的底物范围使该方法对现有的芳基或杂芳基磺酰氯合成方法具有吸引力和互补性.
DOI:10.1016/j.Tetlet.2009.11.047

专利信息

专利号:US-2022363662-A1
优先权日:2021-04-20
标题 :Compounds as lxr agonists
发明人：PUJALA BRAHMAM; SATHE BALAJI DASHRATH; DANODIA ABHINANDAN; GUPTA ASHU; SONI SANJEEV; KUMAR VIVEK; ANSARI AMANTULLAH; KHAN FARHA; SARKAR ARINDAM; PAYGHAN PAVAN V
权利人:INTEGRAL BIOSCIENCES PRIVATED LTD
摘要:The present invention generally discloses compounds having LXR (the liver X receptor) agonistic activity, to the use of such compounds in the treatment of various disorders such as proliferative disorders, Alzheimer's disease, inflammatory diseases, and diseases characterized by defects in cholesterol and lipid metabolism. Specifically, the present invention discloses compound of formula (IA) which exhibit LXR agonist activity, specifically to LXRβ. The invention also discloses method of synthesis of said compounds, method of using said compounds, pharmaceutical compositions comprising said compounds and method of using thereof.

专利号:US-10125226-B2
优先权日:2013-06-05
标 题 :Scale-up process of bifunctionalized triblock copolymers with secondary and tertiary amines, with application in dewatering and desalting of heavy crude oils
发明人：FLORES SANDOVAL CESAR ANDRES; FLORES OROPEZA EUGENIO ALEJANDRO; LOPEZ ORTEGA ALFONSO; HERNANDEZ CORTEZ JOSE GONZALO; ESTRADA BUENDIA ARISTEO; CASTRO SOTELO LAURA VERONICA; REYES MARTINEZ REYNA; ALVAREZ RAMIREZ FERNANDO; ESTRADA MARTINEZ ARQUIMEDES; VAZQUEZ MORENO FLAVIO SALVADOR
权利人:MEXICANO INST PETROL
摘要:A chemical synthesis process is provided for the functionalization of monodispersed triblock copolymer (POEw-POPy-POEw) with secondary or tertiary amines at a semi-industrial level in glass reactors having a capacity between 1 L and 100 L. The process includes two stages where the first stage uses an alkylsulfonyl or arylsulfonyl chloride to obtain better leaving groups, and the second stage is the nucleophilic substitution with secondary or tertiary amines, to obtain the bifunctionalized triblock copolymers. The main advantage for this process is to reduce the quantity of unitary process done in each stage, the optimization of reaction times, and the stoichiometric relationships.

专利号:CN-117720498-A
优先权日:2023-11-03
标 题 :Synthesis of a new coumarin derivative containing a sulfonamide fragment and preparation method and application of its composition

专利号:US-8372971-B2
优先权日:2004-08-25
标 题:Heterocyclic compounds and methods of use
发明人：WRASIDLO WOLFGANG; DNEPROVSKAIA ELENA
权利人:TARGEGEN INC; WRASIDLO WOLFGANG; DNEPROVSKAIA ELENA
摘要:Heterocyclic compounds derived from benzotriazine, triazines, triazoles and oxadiazoles are disclosed. The methods of synthesis and of use of such heterocyclic compounds are also provided.

专利号:CN-119320374-A
优先权日:2024-11-04
标 题 :A method for photocatalytic synthesis of 3-sulfonyl-substituted chromone derivatives

专利号:WO-2020236411-A1
优先权日:2019-05-17
标 题 :A scalable synthesis of dual-target inhibitor of cannabinoid-1 receptor and inducible nitric oxide synthase