CAS: 625-04-7; 4-Amino-4-Methyl-2-Pentanone

该化合物是一种多用途有机化合物,具有氨基和氯酮功能组,使其成为合成化学中有价值的中间体.其结构使合成药物,农用化学品和特殊化学品能够应用.该化合物的活性允许有选择地修改,有利于复杂分子的生产.由于平衡的极度和中度稳定,它适合一系列反应条件,包括还原反应和凝聚反应.与氨基功能相邻的甲基组的存在,加强了合成途径的消毒控制.该化合物由于对水和空气的敏感性,通常在受控制的条件下处理.

结构式图片

上下游产品

CAS号141-79-7 异丙叉丙酮 | CAS号67-64-1 丙酮 | CAS号41608-07-5 2-(Tetradecylox... | CAS号625-03-6 4-氨基-4-甲基-2-戊酮草酸盐 | CAS号27248-25-5 4-isothi°Cyanat... | CAS号7647-01-0 盐酸 | CAS号826-36-8 四甲基哌啶酮 | CAS号4158-85-4 2,2,5-trimethyl... | CAS号7664-41-7 氨 | CAS号4404-98-2 4-氨基-4-甲基-2-戊醇 | CAS号64-18-6 甲酸 | CAS号62-57-7 2-氨基异丁酸 | CAS号516-06-3 DL-缬氨酸 | CAS号27248-25-5 4-isothi°Cyanat... | CAS号826-36-8 四甲基哌啶酮 | CAS号141-79-7 异丙叉丙酮 | CAS号7664-41-7 氨 | CAS号123-42-2 二丙酮醇 | CAS号16504-29-3 6-hydroxy-4,4,6...

合成工艺路线路线简述

  • 合成目标产物 4-Amino-4-Methyl-2-Pentanone Hydrogenoxalate 主要起始原料 Acetone
  • (文献来源)合成步骤主要原料 Acetone
📜4-甲基-3戊烯-2-酮置于氨体系中,用 水 作为反应溶剂,化学反应 15.0H,反应生成 双丙酮胺草酸盐
参考文献:Methods And Compositions For Treating Amyloid-Related Diseases
标题:Methods And Compositions For Treating Amyloid-Related Diseases
摘要:描述了用于治疗或预防与淀粉样蛋白相关疾病的方法,化合物,药物组合物和试剂盒.

海关参考信息

专利信息


专利号:US-6646127-B2
优先权日:2000-10-03
标 题:Process for the synthesis of 2,2,6,6-tetramethyl-4-oxopiperidine
发明人:MALZ JR RUSSELL E; SON YOUNG-CHAN; SUIB STEVEN L
权利人:UNIROYAL CHEM CO INC; UNIV CONNECTICUT
摘要:A process for the synthesis of 2,2,6,6-tetramethyl-4-oxopiperidine is disclosed wherein the process comprises reacting in a liquid phase reaction mixture:A) at least one acetone compound, andB) at least one ammonia donor compound,in the presence of a catalytically effective amount of a crystalline aluminosilicate containing calcium.

专利号:US-4356308-A
优先权日:1980-04-05
标 题 :Process for the preparation of 2,2,6,6-tetramethylpiperidone-4
发明人:WIEZER HARTMUT; NOWY GUENTHER; HAEBERLEIN HARALD
权利人:HOECHST AG
摘要:In the synthesis of 2,2,6,6-tetramethylpiperidone-4 (triacetone-amine) from acetone and ammonia, a partially halogenated or perhalogenated aliphatic or cyclic hydrocarbon is used as catalyst in an amount of from 0.01 to 5 mol %, relative to acetone.

专利号:US-10807954-B2
优先权日:2018-12-07
标 题:Method for preparing triacetone amine
发明人:MINKE KATHARINA; RIEB JULIA; NEUMANN MANFRED
权利人:EVONIK OPERATIONS GMBH
摘要:An improved method is used for preparing triacetone amine while recycling the by-products. This involves treating the crude product from triacetone amine preparation, which leads to an increase in the content of compounds which react readily with ammonia. This method enables efficient recycling of the by-products formed in the synthesis of triacetone amine.

专利号:EP-1480952-A4
优先权日:2000-10-03
标 题 :PROCESS FOR THE SYNTHESIS OF 2,2,6,6-TETRAMETHYL-4-OXOPIPERIDINE

专利号:US-11731940-B2
优先权日:2020-05-07
标 题:Process for preparing triacetonamine
发明人:MINKE KATHARINA; GRASKAMP HOLGER
权利人:EVONIK OPERATIONS GMBH
摘要:An improved process can be used for preparing triacetonamine. The process involves performing an absorption step in which acetone present in the crude product is removed from triacetonamine by distillation, and in gaseous form is then absorbed in countercurrent into fresh, liquid acetone. The acetone stream thus obtained is then converted further to triacetonamine. This process enables more energy-efficient reutilization of the unreacted reactants used in the synthesis of triacetonamine, and thus lowers overall both the use of reactants and the energy expenditure.

专利号:WO-0228833-A2
优先权日:2000-10-03
标题 :Process for the synthesis of 2,2,6,6-tetramethyl-4-oxopiperidine

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

合成参考文献


参考文献:10.5281/zenodo.5794106
摘要:The LOTUS Initiative for Open Natural Products Research: frozen dataset union wikidata (with metadata) | DOI:10.5281/zenodo.5794106
参考文献:10.1107/s1600536808042396
摘要:Ji Z, Wei S, Wu W. Bis(4-ammonio-4-methylpentan-2-one-κO)dioxalato-κ4O1,O2-copper(II). Acta Crystallogr E Struct Rep Online. 2009 Jan 14;65(2):m182. doi: 10.1107/s1600536808042396.
参考文献:10.1107/s1600536809027007
摘要:Rafique M, Hussain G, Siddiqui WA, Tahir MN. 2-Methyl-4-oxopentan-2-aminium 2-sulfamoylbenzoate. Acta Crystallogr Sect E Struct Rep Online. 2009 Jul 18;65(Pt 8):o1883.
📝 需求与反馈
尽可能描述清楚需求与问题信息
×

通知